Next Article in Journal
Photocatalytic, Antimicrobial and Biocompatibility Features of Cotton Knit Coated with Fe-N-Doped Titanium Dioxide Nanoparticles
Previous Article in Journal
Imperfection Sensitivity of Nonlinear Vibration of Curved Single-Walled Carbon Nanotubes Based on Nonlocal Timoshenko Beam Theory
Article Menu
Issue 9 (September) cover image

Export Article

Open AccessArticle
Materials 2016, 9(9), 793;

Highly Absorbent Antibacterial Hemostatic Dressing for Healing Severe Hemorrhagic Wounds

Innovation Platform of Intelligent and Energy-Saving Textiles, School of Textiles, Tianjin Polytechnic University, Tianjin 300387, China
Department of Chemistry and Chemical Engineering, Minjiang University, Fuzhou 350108, China
Graduate Institute of Biotechnology and Biomedical Engineering, Central Taiwan University of Science and Technology, Taichung 40601, Taiwan
Laboratory of Fiber Application and Manufacturing, Department of Fiber and Composite Materials, Feng Chia University, Taichung 40724, Taiwan
Department of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology, Taichung 40601, Taiwan
Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung 40402, Taiwan
School of Chinese Medicine, China Medical University, Taichung 40402, Taiwan
Department of Fashion Design, Asia University, Taichung 41354, Taiwan
Author to whom correspondence should be addressed.
Academic Editor: Carsten Werner
Received: 7 June 2016 / Revised: 28 July 2016 / Accepted: 9 September 2016 / Published: 21 September 2016
Full-Text   |   PDF [3689 KB, uploaded 21 September 2016]   |  


To accelerate healing of severe hemorrhagic wounds, a novel highly absorbent hemostatic dressing composed of a Tencel®/absorbent-cotton/polylactic acid nonwoven base and chitosan/nanosilver antibacterial agent was fabricated by using a nonwoven processing technique and a freeze-drying technique. This study is the first to investigate the wicking and water-absorbing properties of a nonwoven base by measuring the vertical wicking height and water absorption ratio. Moreover, blood agglutination and hemostatic second tests were conducted to evaluate the hemostatic performance of the resultant wound dressing. The blending ratio of fibers, areal weight, punching density, and fiber orientation, all significantly influenced the vertical moisture wicking property. However, only the first two parameters markedly affected the water absorption ratio. After the nonwoven base absorbed blood, scanning electron microscope (SEM) observation showed that erythrocytes were trapped between the fibrin/clot network and nonwoven fibers when coagulation pathways were activated. Prothrombin time (PT) and activated partial thromboplastin time (APTT) blood agglutination of the resultant dressing decreased to 14.34 and 50.94 s, respectively. In the femoral artery of the rate bleeding model, hemostatic time was saved by 87.2% compared with that of cotton cloth. Therefore, the resultant antibacterial wound dressing demonstrated greater water and blood absorption, as well as hemostatic performance, than the commercially available cotton cloth, especially for healing severe hemorrhagic wounds. View Full-Text
Keywords: nonwoven; fiber technology; nanosilver; hemostatic; wound dressing nonwoven; fiber technology; nanosilver; hemostatic; wound dressing

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Li, T.-T.; Lou, C.-W.; Chen, A.-P.; Lee, M.-C.; Ho, T.-F.; Chen, Y.-S.; Lin, J.-H. Highly Absorbent Antibacterial Hemostatic Dressing for Healing Severe Hemorrhagic Wounds. Materials 2016, 9, 793.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Materials EISSN 1996-1944 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top