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Materials 2016, 9(8), 678;

Chemical and Structural Characterization of Several Mid-Term Explanted Breast Prostheses

Dipartimento di Scienze Chimiche, Complesso Universitario di Monte Sant’Angelo, Via Cinthia, Napoli 80100, Italy
CNR-IMM, Istituto per la Microelettronica e Microsistemi, Unità di Napoli, Via P. Castellino 111, Napoli 80131, Italy
Dipartimento di Patologia Sistematica, University of Napoli “Federico II”, Via S. Pansini 5, Napoli 80131, Italy
Author to whom correspondence should be addressed.
Academic Editor: Marco Salerno
Received: 20 June 2016 / Revised: 15 July 2016 / Accepted: 2 August 2016 / Published: 9 August 2016
(This article belongs to the Section Biomaterials)
Full-Text   |   PDF [969 KB, uploaded 9 August 2016]   |  


The recent scandal of poly implant prostheses (PIP), which were found in some cases to be made of non-medical grade silicone (as reported by the European Scientific Committee on Emerging and Newly Identified Health Risks), had a great social impact. Thousands of patients asked for implant removal with significant costs for public health care systems. We analysed, by a multidisciplinary approach, sixteen different breast implants after explantation by using several analytical and structural techniques, such as Fourier Transform infrared spectroscopy (FT-IR), mass spectrometry equipped by ion coupled plasma (ICP-MS), gas-chromatography (GC-MS), and tensile testing. Traces of organic (fatty acid) and inorganic (Fe, Cr, Pt, Na, and other metals) substances were found in all samples, and, even if these values are under danger threshold levels, our study results highlight the possibility of bioaccumulation and tissue contamination, implying the need for continuous medical surveillance and monitoring of material aging. View Full-Text
Keywords: breast implants; organic and inorganic contamination; materials science breast implants; organic and inorganic contamination; materials science

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Amoresano, A.; De Stefano, L.; Rea, I.; Pane, F.; Birolo, L.; Schonauer, F. Chemical and Structural Characterization of Several Mid-Term Explanted Breast Prostheses. Materials 2016, 9, 678.

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