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Vaccinium meridionale Swartz Supercritical CO2 Extraction: Effect of Process Conditions and Scaling Up

Institute of Food Science Research CIAL (CSIC-UAM)—CEI UAM + CSIC, Madrid 28049, Spain
INTAL Foundation Cra 50 G N° 12 Sur 91, Itagüí 050023, Colombia
Author to whom correspondence should be addressed.
Academic Editor: Carlos Manuel Silva
Materials 2016, 9(7), 519;
Received: 11 March 2016 / Revised: 14 June 2016 / Accepted: 20 June 2016 / Published: 25 June 2016
(This article belongs to the Special Issue Optimisation and Scale-Up of Supercritical Fluid Extraction Processes)
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Vaccinium meridionale Swartz (Mortiño or Colombian blueberry) is one of the Vaccinium species abundantly found across the Colombian mountains, which are characterized by high contents of polyphenolic compounds (anthocyanins and flavonoids). The supercritical fluid extraction (SFE) of Vaccinium species has mainly focused on the study of V. myrtillus L. (blueberry). In this work, the SFE of Mortiño fruit from Colombia was studied in a small-scale extraction cell (273 cm3) and different extraction pressures (20 and 30 MPa) and temperatures (313 and 343 K) were investigated. Then, process scaling-up to a larger extraction cell (1350 cm3) was analyzed using well-known semi-empirical engineering approaches. The Broken and Intact Cell (BIC) model was adjusted to represent the kinetic behavior of the low-scale extraction and to simulate the large-scale conditions. Extraction yields obtained were in the range 0.1%–3.2%. Most of the Mortiño solutes are readily accessible and, thus, 92% of the extractable material was recovered in around 30 min. The constant CO2 residence time criterion produced excellent results regarding the small-scale kinetic curve according to the BIC model, and this conclusion was experimentally validated in large-scale kinetic experiments. View Full-Text
Keywords: supercritical fluid extraction; Vaccinium meridionale Swartz; extracts; scale-up supercritical fluid extraction; Vaccinium meridionale Swartz; extracts; scale-up

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López-Padilla, A.; Ruiz-Rodriguez, A.; Restrepo Flórez, C.E.; Rivero Barrios, D.M.; Reglero, G.; Fornari, T. Vaccinium meridionale Swartz Supercritical CO2 Extraction: Effect of Process Conditions and Scaling Up. Materials 2016, 9, 519.

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