Next Article in Journal / Special Issue
Tissue Equivalents Based on Cell-Seeded Biodegradable Microfluidic Constructs
Previous Article in Journal
Hybrid Integrated Platforms for Silicon Photonics
Previous Article in Special Issue
Injectable, Biodegradable Hydrogels for Tissue Engineering Applications
Open AccessReview

Surface Engineering and Patterning Using Parylene for Biological Applications

1
Department of Biomedical Engineering, Cornell University, Ithaca, New York, NY 14853, USA
2
School of Applied and Engineering Physics, Cornell University, Ithaca, New York, NY 14853, USA
*
Author to whom correspondence should be addressed.
Materials 2010, 3(3), 1803-1832; https://doi.org/10.3390/ma3031803
Received: 1 February 2010 / Accepted: 11 March 2010 / Published: 15 March 2010
(This article belongs to the Special Issue Advances in Biomaterials)
Parylene is a family of chemically vapour deposited polymer with material properties that are attractive for biomedicine and nanobiotechnology. Chemically inert parylene “peel-off” stencils have been demonstrated for micropatterning biomolecular arrays with high uniformity, precise spatial control down to nanoscale resolution. Such micropatterned surfaces are beneficial in engineering biosensors and biological microenvironments. A variety of substituted precursors enables direct coating of functionalised parylenes onto biomedical implants and microfluidics, providing a convenient method for designing biocompatible and bioactive surfaces. This article will review the emerging role and applications of parylene as a biomaterial for surface chemical modification and provide a future outlook. View Full-Text
Keywords: parylene; micropatterning; surface modification; [2.2]paracyclophane; biomaterial; bioactive; biomolecular; nanobiotechnology; microarray; microfluidic parylene; micropatterning; surface modification; [2.2]paracyclophane; biomaterial; bioactive; biomolecular; nanobiotechnology; microarray; microfluidic
Show Figures

Graphical abstract

MDPI and ACS Style

Tan, C.P.; Craighead, H.G. Surface Engineering and Patterning Using Parylene for Biological Applications. Materials 2010, 3, 1803-1832.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop