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Micro- and Nanoscale Hydrogel Systems for Drug Delivery and Tissue Engineering

Department of Chemistry, Fordham University / 441 East Fordham Road, New York 10458, USA
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Materials 2009, 2(2), 577-612; https://doi.org/10.3390/ma2020577
Received: 1 March 2009 / Revised: 11 April 2009 / Accepted: 6 May 2009 / Published: 13 May 2009
(This article belongs to the Special Issue Biocompatibility of Materials)
The pursuit for targeted drug delivery systems has led to the development of highly improved biomaterials with enhanced biocompatibility and biodegradability properties. Micro- and nanoscale components of hydrogels prepared from both natural and artificial components have been gaining significant importance due to their potential uses in cell based therapies, tissue engineering, liquid micro-lenses, cancer therapy, and drug delivery. In this review some of the recent methodologies used in the preparation of a number of synthetic hydrogels such as poly(N-isopropylacrylamide) (pNIPAm), poly(ethylene glycol) (PEG), poly(ethylene oxide) (PEO), polyvinyl alcohol methylacrylate co-polymers (PVA-MA) and polylactic acid (PLA), as well as some of the natural hydrogels and their applications have been discussed in detail. View Full-Text
Keywords: hydrogel; micro; nano; drug delivery; tissue engineering; cancer therapy; diabetes; biosensor hydrogel; micro; nano; drug delivery; tissue engineering; cancer therapy; diabetes; biosensor
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Schwall, C.T.; Banerjee, I.A. Micro- and Nanoscale Hydrogel Systems for Drug Delivery and Tissue Engineering. Materials 2009, 2, 577-612.

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