Next Article in Journal
Histomorphometric Evaluation of Peri-Implant Bone Response to Intravenous Administration of Zoledronate (Zometa®) in an Osteoporotic Rat Model
Previous Article in Journal
Investigation of the Mechanical Properties of Mn-Alloyed Tin-Silver-Copper Solder Solidified with Different Cooling Rates
Article

Composite and Surface Functionalization of Ultrafine-Grained Ti23Zr25Nb Alloy for Medical Applications

1
Institute of Materials Science and Engineering, Poznan University of Technology, Jana Pawła II 24, 61-138 Poznan, Poland
2
Division of Mother’s and Child’s Health, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, Poland
3
Department of Gynaecology and Obstetrics, Division of Reproduction, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, Poland
*
Author to whom correspondence should be addressed.
Materials 2020, 13(22), 5252; https://doi.org/10.3390/ma13225252
Received: 24 October 2020 / Revised: 6 November 2020 / Accepted: 18 November 2020 / Published: 20 November 2020
In this study, the ultrafine-grained Ti23Zr25Nb-based composites with 45S5 Bioglass and Ag, Cu, or Zn additions were produced by application of the mechanical alloying technique. Additionally, the base Ti23Zr25Nb alloy was electrochemically modified in the two stages of processing: electrochemical etching in the solution of H3PO4 and HF followed by electrochemical deposition in Ca(NO3)2, (NH4)2HPO4, and HCl. The in vitro cytocompatibility studies were also done with comparison to the commercially pure titanium. The established cell lines of Normal Human Osteoblasts (NHost, CC-2538) and Human Periodontal Ligament Fibroblasts (HPdLF, CC-7049) were used. The culture was conducted among the tested materials. Ultrafine-grained titanium-based composites modified with 45S5 Bioglass and Ag, Cu, or Zn metals have higher biocompatibility than the reference material in the form of a microcrystalline Ti. Proliferation activity was at a stable level with contact with studied materials. In vitro evaluation research showed that the ultrafine-grained Ti23Zr25Nb-based composites with 45S5 Bioglass and Ag, Cu, or Zn additions, with a Young modulus below 50 GPa, can be further used in the biomedical field. View Full-Text
Keywords: Ti alloys; 45S5 Bioglass; metal matrix composites; electrochemical deposition; cell proliferation Ti alloys; 45S5 Bioglass; metal matrix composites; electrochemical deposition; cell proliferation
Show Figures

Graphical abstract

MDPI and ACS Style

Marczewski, M.; Jurczyk, M.U.; Kowalski, K.; Miklaszewski, A.; Wirstlein, P.K.; Jurczyk, M. Composite and Surface Functionalization of Ultrafine-Grained Ti23Zr25Nb Alloy for Medical Applications. Materials 2020, 13, 5252. https://doi.org/10.3390/ma13225252

AMA Style

Marczewski M, Jurczyk MU, Kowalski K, Miklaszewski A, Wirstlein PK, Jurczyk M. Composite and Surface Functionalization of Ultrafine-Grained Ti23Zr25Nb Alloy for Medical Applications. Materials. 2020; 13(22):5252. https://doi.org/10.3390/ma13225252

Chicago/Turabian Style

Marczewski, Mateusz, Mieczysława U. Jurczyk, Kamil Kowalski, Andrzej Miklaszewski, Przemysław K. Wirstlein, and Mieczysław Jurczyk. 2020. "Composite and Surface Functionalization of Ultrafine-Grained Ti23Zr25Nb Alloy for Medical Applications" Materials 13, no. 22: 5252. https://doi.org/10.3390/ma13225252

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop