Assessing the Mechanical Weakness of Vertebrae Affected by Primary Tumors: A Feasibility Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Protocol
- The specimen can stay in air only two hours to not modify the biological characteristics, after that the specimen must be fixed in formalin solution (also if the tests are not completed);
- The specimen must not be fractured or damaged to not compromise the evaluation of the margins of the tumor and the histological analysis.
2.2. Cases
2.3. Mechanical Tests
2.4. Strain Measurements
3. Results
4. Discussion
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Case | Age | Sex | Tumors | Vertebra | Grade | Local Extensions | 6-Point ESCC | SINS | Margins Classification | Presence of Metastasis | Months between Diagnosis and Surgery | Previous Therapy | Current Therapy |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
#1 | 62 | M | Chordoma | T12 | IB | 7–10 | 1B | 11 | Focal margin, in the posterior part of the specimen. Wide, the other margins | NO | 2 | None | None |
#2 | 22 | M | Ewing’s sarcoma | L3 | IIB | 2–6 | 0 | 4 | Wide (Necrosis 40%, Bologna system 1) | NO | 4 | Chemotherapy | Chemotherapy and Radiotherapy |
#3 | 11 | F | Ewing’s sarcoma | L3 | IIB | 7–11 | 1A | 6 | Wide (Necrosis 80%, Bologna system 1) | NO | 6 | Chemotherapy | Chemotherapy and Radiotherapy |
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Palanca, M.; Cristofolini, L.; Gasbarrini, A.; Tedesco, G.; Barbanti-Bròdano, G. Assessing the Mechanical Weakness of Vertebrae Affected by Primary Tumors: A Feasibility Study. Materials 2020, 13, 3256. https://doi.org/10.3390/ma13153256
Palanca M, Cristofolini L, Gasbarrini A, Tedesco G, Barbanti-Bròdano G. Assessing the Mechanical Weakness of Vertebrae Affected by Primary Tumors: A Feasibility Study. Materials. 2020; 13(15):3256. https://doi.org/10.3390/ma13153256
Chicago/Turabian StylePalanca, Marco, Luca Cristofolini, Alessandro Gasbarrini, Giuseppe Tedesco, and Giovanni Barbanti-Bròdano. 2020. "Assessing the Mechanical Weakness of Vertebrae Affected by Primary Tumors: A Feasibility Study" Materials 13, no. 15: 3256. https://doi.org/10.3390/ma13153256