Next Article in Journal
Electronic Nose: Recent Developments in Gas Sensing and Molecular Mechanisms of Graphene Detection and Other Materials
Previous Article in Journal
A Novel Mechanical Metamaterial Exhibiting Auxetic Behavior and Negative Compressibility
Open AccessArticle

Enhanced Antibacterial Property of Facet-Engineered TiO2 Nanosheet in Presence and Absence of Ultraviolet Irradiation

1
Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8549, Japan
2
State Key Laboratory of Fine Chemicals, School of Petroleum and Chemical Engineering, Dalian University of Technology, Panjin 124221, China
3
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Chiyoda-ku, Tokyo 101-0062, Japan
4
Joining and Welding Research Institute, Osaka University, 11-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan
*
Author to whom correspondence should be addressed.
Materials 2020, 13(1), 78; https://doi.org/10.3390/ma13010078
Received: 28 November 2019 / Revised: 17 December 2019 / Accepted: 18 December 2019 / Published: 22 December 2019
(This article belongs to the Section Biomaterials)
Titania (TiO2) has attracted much attention recently for reducing bacterial diseases by the generation of reactive oxygen species (ROS) under UV irradiation. However, demand for higher photocatalytic activity due to higher recombination of electron and hole remains. The aims of this study were to make titania with higher antibacterial property and show the mechanisms of the bactericidal effect. In this study, we hydrothermally synthesized TiO2 nanosheets (NS) with highly-oriented structures. Samples were divided into five groups, depending on the fluorine/titanium ratio in the raw material, namely NS1.0, NS1.2, NS1.5, NS1.8, and NS2.0. Facet ratio and nanosheet size increased with an increase of fluorine/titanium ratio. The photocatalytic activity of TiO2 nanosheet was assessed by the generation of ROS. Hydroxyl radicals and superoxides were generated efficiently by ultraviolet light irradiation on NS1.5 and NS1.0, respectively. Antibacterial activity against Streptococcus mutans was assessed in the presence and absence of UV irradiation; NS1.0 showed superior antibacterial properties compared to commercially available TiO2 nanoparticles, under both conditions, due to the oxidation of intracellular components and cell membrane. These results together suggested TiO2 nanosheet induced bacterial cell death by oxidation, and TiO2 facet engineering resulted in enhancement of both photocatalytic and antibacterial activities of TiO2. View Full-Text
Keywords: TiO2; facet engineering; photocatalytic activity; antibacterial activity TiO2; facet engineering; photocatalytic activity; antibacterial activity
Show Figures

Graphical abstract

MDPI and ACS Style

Hayashi, K.; Nozaki, K.; Tan, Z.; Fujita, K.; Nemoto, R.; Yamashita, K.; Miura, H.; Itaka, K.; Ohara, S. Enhanced Antibacterial Property of Facet-Engineered TiO2 Nanosheet in Presence and Absence of Ultraviolet Irradiation. Materials 2020, 13, 78. https://doi.org/10.3390/ma13010078

AMA Style

Hayashi K, Nozaki K, Tan Z, Fujita K, Nemoto R, Yamashita K, Miura H, Itaka K, Ohara S. Enhanced Antibacterial Property of Facet-Engineered TiO2 Nanosheet in Presence and Absence of Ultraviolet Irradiation. Materials. 2020; 13(1):78. https://doi.org/10.3390/ma13010078

Chicago/Turabian Style

Hayashi, Kenichiro; Nozaki, Kosuke; Tan, Zhenquan; Fujita, Kazuhisa; Nemoto, Reina; Yamashita, Kimihiro; Miura, Hiroyuki; Itaka, Keiji; Ohara, Satoshi. 2020. "Enhanced Antibacterial Property of Facet-Engineered TiO2 Nanosheet in Presence and Absence of Ultraviolet Irradiation" Materials 13, no. 1: 78. https://doi.org/10.3390/ma13010078

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop