Comparison of Teriparatide and Combination of Cissus Quadrangularis and Dalbergia Sissoo on Bone Healing Against the Control Group in Maxillofacial Fractures: A Randomized Open-Label Control Trial
Abstract
:Introduction
Materials and Methods
Trial Design
Settings and Consents
Eligibility Criteria
Sample Size Calculation
Randomization, Allocation Concealment, and Blinding
Intervention
Outcome Measures
- The pain was evaluated using a numerical rating scale (NRS) score preoperatively and postoperatively at first week, second week, fourth week, and sixth week.
- Fracture site mobility was evaluated preoperatively and postoperatively at first week, fourth week, and eighth week.
- In our study, we had used Flexi-force sensor for recording bite force which was standardized and calibrated by evaluating 20 healthy individuals. The mean ABF and PBF were recorded —140 N and 350 N, and these values were used for further comparison. ABF and PBF measurement was done in all the patients preoperatively and postoperatively at first week, second week, fourth week, sixth week, eighth week, and 12th week.
- Serum osteogenic markers (Ca, PTH, and ALP) were evaluated preoperatively and postoperatively at the fourth week.
Statistical Analysis
Results
Discussion
Limitations of the Study
Funding
Acknowledgments
Declaration of Conflicting Interests
Appendix
Abbreviations | |
ABF | Anterior Bite Force |
PBF | Posterior Bite force |
PTH | Parathormone |
ALP | Alkaline phosphatase |
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© 2022 by the author. The Author(s) 2022.
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PG, G.; Chugh, A.; Chaudhry, K.; Kaur, A.; Kumar, P.; Gaur, S.; Kumar, S.; Singh, S. Comparison of Teriparatide and Combination of Cissus Quadrangularis and Dalbergia Sissoo on Bone Healing Against the Control Group in Maxillofacial Fractures: A Randomized Open-Label Control Trial. Craniomaxillofac. Trauma Reconstr. 2023, 16, 23-33. https://doi.org/10.1177/19433875211067007
PG G, Chugh A, Chaudhry K, Kaur A, Kumar P, Gaur S, Kumar S, Singh S. Comparison of Teriparatide and Combination of Cissus Quadrangularis and Dalbergia Sissoo on Bone Healing Against the Control Group in Maxillofacial Fractures: A Randomized Open-Label Control Trial. Craniomaxillofacial Trauma & Reconstruction. 2023; 16(1):23-33. https://doi.org/10.1177/19433875211067007
Chicago/Turabian StylePG, Gigi, Ankita Chugh, Kirti Chaudhry, Amanjot Kaur, Pravin Kumar, Shubham Gaur, Shailendra Kumar, and Surjit Singh. 2023. "Comparison of Teriparatide and Combination of Cissus Quadrangularis and Dalbergia Sissoo on Bone Healing Against the Control Group in Maxillofacial Fractures: A Randomized Open-Label Control Trial" Craniomaxillofacial Trauma & Reconstruction 16, no. 1: 23-33. https://doi.org/10.1177/19433875211067007
APA StylePG, G., Chugh, A., Chaudhry, K., Kaur, A., Kumar, P., Gaur, S., Kumar, S., & Singh, S. (2023). Comparison of Teriparatide and Combination of Cissus Quadrangularis and Dalbergia Sissoo on Bone Healing Against the Control Group in Maxillofacial Fractures: A Randomized Open-Label Control Trial. Craniomaxillofacial Trauma & Reconstruction, 16(1), 23-33. https://doi.org/10.1177/19433875211067007