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Why I Chose to Use Cannabis
Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
Article

Integrating Cannabis into Clinical Cancer Care

University of California–San Francisco, San Francisco, CA, USA
Curr. Oncol. 2016, 23(s1), 8-14; https://doi.org/10.3747/co.23.3099
Received: 11 December 2015 / Revised: 6 January 2016 / Accepted: 9 February 2016 / Published: 1 March 2016
Cannabis species have been used as medicine for thousands of years; only since the 1940s has the plant not been widely available for medical use. However, an increasing number of jurisdictions are making it possible for patients to obtain the botanical for medicinal use. For the cancer patient, cannabis has a number of potential benefits, especially in the management of symptoms. Cannabis is useful in combatting anorexia, chemotherapy-induced nausea and vomiting, pain, insomnia, and depression. Cannabis might be less potent than other available antiemetics, but for some patients, it is the only agent that works, and it is the only antiemetic that also increases appetite. Inhaled cannabis is more effective than placebo in ameliorating peripheral neuropathy in a number of conditions, and it could prove useful in chemotherapy-induced neuropathy. A pharmacokinetic interaction study of vaporized cannabis in patients with chronic pain on stable doses of sustained-release opioids demonstrated no clinically significant change in plasma opiates, while suggesting the possibility of synergistic analgesia. Aside from symptom management, an increasing body of in vitro and animal-model studies supports a possible direct anticancer effect of cannabinoids by way of a number of different mechanisms involving apoptosis, angiogenesis, and inhibition of metastasis. Despite an absence of clinical trials, abundant anecdotal reports that describe patients having remarkable responses to cannabis as an anticancer agent, especially when taken as a high-potency orally ingested concentrate, are circulating. Human studies should be conducted to address critical questions related to the foregoing effects.
Keywords: Cannabis; cannabinoids; symptom management; nausea; anorexia; pain Cannabis; cannabinoids; symptom management; nausea; anorexia; pain
MDPI and ACS Style

Abrams, D.I. Integrating Cannabis into Clinical Cancer Care. Curr. Oncol. 2016, 23, 8-14. https://doi.org/10.3747/co.23.3099

AMA Style

Abrams DI. Integrating Cannabis into Clinical Cancer Care. Current Oncology. 2016; 23(s1):8-14. https://doi.org/10.3747/co.23.3099

Chicago/Turabian Style

Abrams, D.I. 2016. "Integrating Cannabis into Clinical Cancer Care" Current Oncology 23, no. s1: 8-14. https://doi.org/10.3747/co.23.3099

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