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Current Oncology
Volume 19
Issue 1
10.3747/co.19.840
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Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
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Case Report

Medullary Thyroid Cancer and Pseudocirrhosis: Case Report and Literature Review

by
B.L. Harry
1,
M.L. Smith
2,
J.R. Burton
3,
A. Dasari
4,
S.G. Eckhardt
4 and
J.R. Diamond
4,*
1
Medical Scientist Training Program, University of Colorado at Denver, Anschutz Medical Campus, Aurora, CO, USA
2
Departments of Pathology and Medicine, University of Colorado at Denver, Anschutz Medical Campus, Aurora, CO, USA
3
Division of Gastroenterology, University of Colorado at Denver, Anschutz Medical Campus, Aurora, CO, USA
4
Division of Medical Oncology, University of Colorado at Denver, Anschutz Medical Campus, Aurora, CO, USA
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2012, 19(1), 36-41; https://doi.org/10.3747/co.19.840
Submission received: 6 November 2011 / Revised: 4 December 2011 / Accepted: 2 January 2012 / Published: 1 February 2012

Abstract

Pseudocirrhosis is a rare form of liver disease that can cause clinical symptoms and radiographic signs of cirrhosis; however, its histologic features suggest a distinct pathologic process. In the setting of cancer, hepatic metastases and systemic chemotherapy are suspected causes of pseudocirrhosis. Here, we present a patient with medullary thyroid carcinoma metastatic to the liver who developed pseudocirrhosis while on maintenance sunitinib after receiving 5-fluorouracil, leucovorin, and oxaliplatin (folfox) in combination with sunitinib. Cirrhotic change in liver morphology was accompanied by diffusely infiltrative carcinomatous disease resembling the primary tumor. We discuss the diagnosis of pseudocirrhosis in this case and review the literature regarding pseudocirrhosis in cancer.
Keywords: medullary thyroid cancer; pseudocirrhosis; carcinomatous cirrhosis medullary thyroid cancer; pseudocirrhosis; carcinomatous cirrhosis

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MDPI and ACS Style

Harry, B.L.; Smith, M.L.; Burton, J.R.; Dasari, A.; Eckhardt, S.G.; Diamond, J.R. Medullary Thyroid Cancer and Pseudocirrhosis: Case Report and Literature Review. Curr. Oncol. 2012, 19, 36-41. https://doi.org/10.3747/co.19.840

AMA Style

Harry BL, Smith ML, Burton JR, Dasari A, Eckhardt SG, Diamond JR. Medullary Thyroid Cancer and Pseudocirrhosis: Case Report and Literature Review. Current Oncology. 2012; 19(1):36-41. https://doi.org/10.3747/co.19.840

Chicago/Turabian Style

Harry, B.L., M.L. Smith, J.R. Burton, A. Dasari, S.G. Eckhardt, and J.R. Diamond. 2012. "Medullary Thyroid Cancer and Pseudocirrhosis: Case Report and Literature Review" Current Oncology 19, no. 1: 36-41. https://doi.org/10.3747/co.19.840

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