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Case Report

Transcoronary Alcohol Ablation—On Behalf of Three Cases with Hypertrophic Obstructive Cardiomyopathy

by
Alexander Breitenstein
*,
Jasmina Alibegovic
,
David Hürlimann
,
Patric Biaggi
,
Roberto Corti
and
Thomas F. Lüscher
Cardiology, Cardiovascular Center, University Hospital Zurich, Zurich, Switzerland
*
Author to whom correspondence should be addressed.
Cardiovasc. Med. 2011, 14(10), 290; https://doi.org/10.4414/cvm.2011.01615
Submission received: 26 July 2011 / Revised: 26 August 2011 / Accepted: 26 September 2011 / Published: 26 October 2011

Abstract

Hypertrophic cardiomyopathy (HCM) is a common genetic disorder with an estimated prevalence of 1:500. About a quarter of the patients with HCM have left ventricular outflow tract obstruction referred to as hypertrophic obstructive cardiomyopathy (HOCM). Even with optimal medical treatment using negative inotropic drugs such as β-blockers and first generation calcium-antagonists, about 5–10% of patients with HOCM remain refractory to therapy. In such cases, reduction of the outflow gradient by either surgical myectomy or catheter-based alcohol septal ablation represent further treatment options. Even though myectomy historically is considered the gold standard, interventional alcohol ablation of the septum has become the treatment of choice in many centres. We present the history of three patients suffering from HOCM, who were successfully treated by catheter-based alcohol septal ablation.
Keywords: hypertrophic cardiomyopathy; transcoronary alcohol ablation hypertrophic cardiomyopathy; transcoronary alcohol ablation

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MDPI and ACS Style

Breitenstein, A.; Alibegovic, J.; Hürlimann, D.; Biaggi, P.; Corti, R.; Lüscher, T.F. Transcoronary Alcohol Ablation—On Behalf of Three Cases with Hypertrophic Obstructive Cardiomyopathy. Cardiovasc. Med. 2011, 14, 290. https://doi.org/10.4414/cvm.2011.01615

AMA Style

Breitenstein A, Alibegovic J, Hürlimann D, Biaggi P, Corti R, Lüscher TF. Transcoronary Alcohol Ablation—On Behalf of Three Cases with Hypertrophic Obstructive Cardiomyopathy. Cardiovascular Medicine. 2011; 14(10):290. https://doi.org/10.4414/cvm.2011.01615

Chicago/Turabian Style

Breitenstein, Alexander, Jasmina Alibegovic, David Hürlimann, Patric Biaggi, Roberto Corti, and Thomas F. Lüscher. 2011. "Transcoronary Alcohol Ablation—On Behalf of Three Cases with Hypertrophic Obstructive Cardiomyopathy" Cardiovascular Medicine 14, no. 10: 290. https://doi.org/10.4414/cvm.2011.01615

APA Style

Breitenstein, A., Alibegovic, J., Hürlimann, D., Biaggi, P., Corti, R., & Lüscher, T. F. (2011). Transcoronary Alcohol Ablation—On Behalf of Three Cases with Hypertrophic Obstructive Cardiomyopathy. Cardiovascular Medicine, 14(10), 290. https://doi.org/10.4414/cvm.2011.01615

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