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Genotoxicity and Carcinogenicity of Medicinal Herbs and Their Nanoparticles

1
Biology Department, Aljumum University College, Umm Al-Qura University, Makkah 2203, Saudi Arabia
2
Biology Department, Faculty of Science, Taibah University, Al-Sharm, Yanbu El-Bahr, Yanbu 46429, Saudi Arabia
*
Author to whom correspondence should be addressed.
Academic Editor: Herbert Ryan Marini
Nutraceuticals 2021, 1(1), 31-41; https://doi.org/10.3390/nutraceuticals1010005
Received: 4 October 2021 / Revised: 5 November 2021 / Accepted: 11 November 2021 / Published: 18 November 2021
Medicinal plants (MPs) account for 70–80% of use in primary care around the world, and this percentage indicates that the number of MP users is high; thus, it is necessary to focus studies on medicinal herbs to ensure their proper use. In addition, MPs have strong genotoxic effects, as some types of MPs can cause DNA damage. Any substance that raises the risk of cancer or a tumor in an organism is called a carcinogen. There are many genotoxic and carcinogenic substances in the environment that can directly or indirectly affect genetic material. There are also nanoparticles (NPs) derived from MPs. Carbon-based NPs contain many nanoscale materials, such as fullerenes and carbon nanotubes, as well as metals such as gold (Au), silver (Ag), and aluminum (Al). Unfortunately, few studies are concerned with the carcinogenicity of NPs from MPs, whereas many researchers are interested in genotoxic assessment. For this reason, there is an urgent need for more studies into the safety of MPs and NPs. Therefore, this study reviewed the genotoxicity and carcinogenicity of MPs and their derived NPs. We also emphasized the need for strict regulation and monitoring of MP usage. View Full-Text
Keywords: genotoxicity; carcinogenicity; nanoparticles; medicinal herbs; DNA damage genotoxicity; carcinogenicity; nanoparticles; medicinal herbs; DNA damage
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MDPI and ACS Style

Qari, S.H.; Alrefaei, A.F.; Ashoor, A.B.; Soliman, M.H. Genotoxicity and Carcinogenicity of Medicinal Herbs and Their Nanoparticles. Nutraceuticals 2021, 1, 31-41. https://doi.org/10.3390/nutraceuticals1010005

AMA Style

Qari SH, Alrefaei AF, Ashoor AB, Soliman MH. Genotoxicity and Carcinogenicity of Medicinal Herbs and Their Nanoparticles. Nutraceuticals. 2021; 1(1):31-41. https://doi.org/10.3390/nutraceuticals1010005

Chicago/Turabian Style

Qari, Sameer H., Abdulmajeed F. Alrefaei, Ahmed B. Ashoor, and Mona H. Soliman. 2021. "Genotoxicity and Carcinogenicity of Medicinal Herbs and Their Nanoparticles" Nutraceuticals 1, no. 1: 31-41. https://doi.org/10.3390/nutraceuticals1010005

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