Urban Environmental Determinants and Spatiotemporal Patterns of Emergency Medical Service Response to Traumatic Injuries: A Five-Year Population-Based Study
Highlights
- Rapid urbanization in emerging economies creates structural barriers to equitable emergency medical service (EMS) access, directly impacting trauma survival rates.
- Traumatic injuries remain a leading cause of premature mortality, requiring optimized prehospital logistics to meet the “Golden Hour” clinical benchmark.
- This study utilizes a robust five-year population-based dataset (N = 26,073) to identify a critical “Accessibility Paradox” where EMS delays are maximal during peak injury hours.
- The research provides the first comprehensive spatiotemporal audit of EMS performance in a major Central Asian capital, uncovering significant health equity gaps.
- Health authorities should transition from population-based to proximity-based EMS deployment models, prioritizing satellite posts in underserved peripheral districts.
- Integrating real-time GIS analytics into urban health policy is essential for reducing preventable trauma-related disability and enhancing urban resilience.
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Design and Data Sources
2.2. EMS Activation and Dispatch Context in Kazakhstan
2.3. Data Quality Assessment and Missing Data
2.4. Statistical Analysis
2.5. Demographic and Temporal Analysis
2.6. Geospatial Data Processing and Geocoding
2.7. Spatial Analysis and Modeling
3. Results
3.1. Demographic Profile and Clinical Outcomes
3.2. Temporal Trends and Performance Audit
3.3. Spatiotemporal Analysis and Accessibility Gap
4. Discussion
4.1. The Demographic Gap and Clinical Acuity
4.2. The Diurnal Paradox and Safety Culture
4.3. Spatial Inequity and the “Old City” Barrier
5. Limitations
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
| AMU | Astana Medical University |
| CI | Confidence Interval |
| df | Degrees of Freedom |
| EMS | Emergency Medical Services |
| GBD | Global Burden of Disease |
| GDP | Gross Domestic Product |
| GIS | Geographic Information System |
| HCF | Healthcare Facility |
| ICD-10 | International Classification of Diseases, 10th Revision |
| IQR | Interquartile Range |
| ISS | Injury Severity Score |
| KDE | Kernel Density Estimation |
| MSHE RK | Ministry of Science and Higher Education of the Republic of Kazakhstan |
| NpJSC | Non-profit Joint-Stock Company |
| OSM | OpenStreetMap |
| SD | Standard Deviation |
| SDG | Sustainable Development Goals |
| SRN | Street and Road Network |
| WHO | World Health Organization |
References
- Liu, T.; Liu, X.; Li, Y.; Wang, A.; Chen, S.; Wu, S.; Hou, S.; Fan, H.; Cao, C. Associations of traumatic injury with abnormal glucose metabolism: A population-based prospective cohort study. Clin. Epidemiol. 2023, 15, 297–307. [Google Scholar] [CrossRef]
- GBD 2021 Diseases and Injuries Collaborators. Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: A systematic analysis for the Global Burden of Disease Study 2021. Lancet 2024, 403, 2133–2161. [Google Scholar] [CrossRef]
- Haagsma, J.A.; Graetz, N.; Bolliger, I.; Naghavi, M.; Higashi, H.; Mullany, E.C.; Abera, S.F.; Abraham, J.P.; Adofo, K.; Alsharif, U.; et al. The Global Burden of Injury: Incidence, Mortality, Disability-Adjusted Life Years and Time Trends from the Global Burden of Disease Study 2013. Inj. Prev. 2016, 22, 3–18. [Google Scholar] [CrossRef] [PubMed]
- Wijnen, W. Socio-economic costs of road crashes in middle-income countries: Applying a hybrid approach to Kazakhstan. IATSS Res. 2021, 45, 293–302. [Google Scholar] [CrossRef]
- Kudryavtsev, S.S.; Yemelin, P.V.; Yemelina, N.K. The development of a risk-management system in the field of industrial safety in the Republic of Kazakhstan. Saf. Health Work 2018, 9, 30–41. [Google Scholar] [CrossRef]
- World Health Organization. Road Traffic Injuries. Available online: https://www.who.int/news-room/fact-sheets/detail/road-traffic-injuries (accessed on 7 August 2025).
- Asfaw, Z.K. National trauma registries in LMICs: Long-overdue priority; comment on “Neurotrauma surveillance in national registries of low- and middle-income countries”. Int. J. Health Policy Manag. 2023, 12, 7504. [Google Scholar] [CrossRef]
- Celso, B.; Tepas, J.; Langland-Orban, B.; Pracht, E.; Papa, L.; Lottenberg, L.; Flint, L. A systematic review and meta-analysis comparing outcome of severely injured patients treated in trauma centers following the establishment of trauma systems. J. Trauma 2006, 60, 371–378. [Google Scholar] [CrossRef]
- World Bank. Socioeconomic Impacts of Road Traffic Injuries in Central Asia; World Bank: Washington, DC, USA, 2022. [Google Scholar]
- World Health Organization. Global Status Report on Road Safety: Time for Action; World Health Organization: Geneva, Switzerland, 2009. [Google Scholar]
- Chen, C.-H.; Shin, S.D.; Sun, J.-T.; Jamaluddin, S.F.; Tanaka, H.; Song, K.-J.; Kajino, K.; Kimura, A.; Huang, E.P.C.; Hsieh, M.-J.; et al. Association between prehospital time and outcome of trauma patients in 4 Asian countries: A cross-national, multicentre cohort study. PLoS Med. 2020, 17, e1003360. [Google Scholar] [CrossRef]
- Cusimano, M.D.; Marshall, S.; Rinner, C.; Jiang, D.; Chipman, M. Patterns of urban violent injury: A spatio-temporal analysis. PLoS ONE 2010, 5, e8669. [Google Scholar] [CrossRef]
- Forrester, J.D.; August, A.; Cai, L.Z.; Kushner, A.L.; Wren, S.M. The golden hour after injury among civilians caught in conflict zones. Disaster Med. Public Health Prep. 2019, 13, 1074–1082. [Google Scholar] [CrossRef] [PubMed]
- World Health Organization. Injuries and Violence: Aiming for the “Golden Hour” of Health-Emergency Response. Available online: https://www.who.int/about/accountability/results/who-results-report-2022-mtr/rapid-reaction-aiming-for-the-golden-hour-of-health-emergency-response (accessed on 7 August 2025).
- Harmsen, A.M.K.; Giannakopoulos, G.F.; Moerbeek, P.R.; Jansma, E.P.; Bonjer, H.J.; Bloemers, F.W. The influence of prehospital time on trauma patients’ outcome: A systematic review. Injury 2015, 46, 602–609. [Google Scholar] [CrossRef]
- World Health Organization. Framework for Strengthening Health Emergency Preparedness in Cities and Urban Settings; World Health Organization: Geneva, Switzerland, 2021; Available online: https://www.who.int/publications/i/item/9789240037830 (accessed on 7 August 2025).
- Alruwaili, A.; Alanazy, A.R.M. Prehospital time interval for urban and rural emergency medical services: A systematic literature review. Healthcare 2022, 10, 2391. [Google Scholar] [CrossRef]
- Lundberg, O.H.M.; Lapidus, O.; Bäckström, D. Prehospital time intervals for trauma patients according to population density levels in Sweden: A national retrospective cohort study. Scand. J. Trauma Resusc. Emerg. Med. 2025, 33, 193. [Google Scholar] [CrossRef]
- Byrne, J.P.; Mann, N.C.; Dai, M.; Mason, S.A.; Karanicolas, P.; Rizoli, S.; Nathens, A.B. Association between emergency medical service response time and motor vehicle crash mortality in the United States. JAMA Surg. 2019, 154, 286–293. [Google Scholar] [CrossRef]
- Jin, Y.; Chen, H.; Ge, H.; Li, S.; Zhang, J.; Ma, Q. Urban–suburb disparities in pre-hospital emergency medical resources and response time among patients with out-of-hospital cardiac arrest: A mixed-method cross-sectional study. Front. Public Health 2023, 11, 1121779. [Google Scholar] [CrossRef] [PubMed]
- Zhao, Y.; Zhou, Y. Isochrone-based accessibility analysis of pre-hospital emergency medical facilities: A case study of central districts of Beijing. ISPRS Int. J. Geo-Inf. 2024, 13, 288. [Google Scholar] [CrossRef]
- Ministry of Health of the Republic of Kazakhstan. In Kazakhstan, 240 Thousand Patients with Various Injuries were Treated in 2024. Available online: https://www.gov.kz/memleket/entities/dsm/press/news/details/999282?lang=ru (accessed on 17 February 2026).
- Mussina, A.; Chayakova, A.; Myrzakhanova, M.; Kydyrmoldina, A.; Tuleshova, G.; Utegenova, A.; Hamidullina, Z.; Volchkova, I.; Moldabayeva, A. Geospatial and temporal analysis of emergency medical services during the COVID-19 pandemic: A case study of Astana, Kazakhstan. Port. J. Public Health 2025, 43, 265–279. [Google Scholar] [CrossRef]
- Lerner, E.B.; Moscati, R.M. The golden hour: Scientific fact or medical “urban legend”? Acad. Emerg. Med. 2001, 8, 758–760. [Google Scholar] [CrossRef]
- Newgard, C.D.; Schmicker, R.H.; Sopko, G.; Andrusiek, D.; Bialkowski, W.; Minei, J.P.; Brasel, K.; Bulger, E.; Fleischman, R.J.; Kerby, J.D.; et al. Trauma in the neighborhood: A geospatial analysis and assessment of social determinants of major injury in North America. Am. J. Public Health 2011, 101, 669–677. [Google Scholar] [CrossRef]
- Walker, B.B.; Schuurman, N.; Hameed, S.M. A GIS-based spatiotemporal analysis of violent trauma hotspots in Vancouver, Canada: Identification, contextualisation and intervention. BMJ Open 2014, 4, e003642. [Google Scholar] [CrossRef]
- Hazaymeh, K.; Almagbile, A.; Alomari, A.H. Spatiotemporal analysis of traffic accidents hotspots based on geospatial techniques. ISPRS Int. J. Geo-Inf. 2022, 11, 260. [Google Scholar] [CrossRef]
- Ministry of Health of the Republic of Kazakhstan. On approval of the Rules for Providing Emergency Medical Care in the Republic of Kazakhstan. Order No. ҚР ДСМ-54/2020. 21 May 2020. Available online: https://adilet.zan.kz/rus/docs/V2000021713#z294 (accessed on 17 February 2026).
- Chen, Z.; Chakrabarty, S.; Levine, R.S.; Aliyu, M.H.; Ding, T.; Jackson, L.L. Work-related knee injuries treated in emergency departments in the United States. J. Occup. Environ. Med. 2013, 55, 1091–1099. [Google Scholar] [CrossRef]
- Thompson, J.; Stevenson, M.; Wijnands, J.S.; Nice, K.A.; Aschwanden, G.D.P.; Silver, J.; Nieuwenhuijsen, M.; Rayner, P.; Schofield, R.; Hariharan, R.; et al. A Global Analysis of Urban Design Types and Road Transport Injury: An Image Processing Study. Lancet Planet. Health 2020, 4, e32–e42. [Google Scholar] [CrossRef]
- Sánchez-Moreno, J.A.; Figueroa-García, J.C. Técnicas de agrupamiento y análisis geoespacial—Estudio comparativo en la línea de emergencia de Bogotá. Cienc. Ing. Neogranadina 2024, 34, 131–146. [Google Scholar] [CrossRef]
- Cantwell, K.; Morgans, A.; Smith, K.; Livingston, M.; Spelman, T.; Dietze, P. Time of day and day of week trends in EMS demand. Prehosp. Emerg. Care 2015, 19, 425–431. [Google Scholar] [CrossRef]
- Hashtarkhani, S.; Matthews, S.A.; Yin, P.; Mohammadi, A.; MohammadEbrahimi, S.; Tara, M.; Kiani, B. Where to place emergency ambulance vehicles: Use of a capacitated maximum covering location model with real call data. Geospat. Health 2023, 18, 1198. [Google Scholar] [CrossRef]
- Odusola, A.O.; Jeong, D.; Malolan, C.; Kim, D.; Venkatraman, C.; Kola-Korolo, O.; Idris, O.; Olaomi, O.O.O.; Nwariaku, F.E. Spatial and temporal analysis of road traffic crashes and ambulance responses in Lagos State, Nigeria. BMC Public Health 2023, 23, 2273. [Google Scholar] [CrossRef]
- Jones, C.M.C.; Cushman, J.T.; Lerner, E.B.; Fisher, S.G.; Seplaki, C.L.; Veazie, P.J.; Wasserman, E.B.; Dozier, A.; Shah, M.N. Prehospital trauma triage decision-making: A model of what happens between the 9-1-1 call and the hospital. Prehosp. Emerg. Care 2016, 20, 6–14. [Google Scholar] [CrossRef]
- Li, M.; Vanberkel, P.; Carter, A.J.E. A review on ambulance offload delay literature. Health Care Manag. Sci. 2019, 22, 658–675. [Google Scholar] [CrossRef]
- Troyer, L.; Brady, W. Barriers to effective EMS to emergency department information transfer at patient handover: A systematic review. Am. J. Emerg. Med. 2020, 38, 1494–1503. [Google Scholar] [CrossRef]
- Evans, C.; Da’Costa, A. A strategic solution to preventing the harm associated with ambulance handover delays. Emerg. Nurse 2024, 32, 15–20. [Google Scholar] [CrossRef] [PubMed]
- Mol, S.; Hageman-van Wamel, J.D.G.; Van der Linden, M.C.; Gaakeer, M.I.; De Ridder, V.A. Waiting time ambulances in the emergency department; a Dutch single center study (WAITED study). Int. J. Emerg. Med. 2025, 18, 251. [Google Scholar] [CrossRef] [PubMed]
- Nasr Isfahani, M.; Emadi, N.; Heydari, F.; Fatemi, N.A.-S.; Sheibani Tehrani, D. Urban traffic accidents in Isfahan city: A study of prehospital response time intervals. Int. J. Emerg. Med. 2024, 17, 201. [Google Scholar] [CrossRef] [PubMed]
- Hill, P.; Lederman, J.; Jonsson, D.; Bolin, P.; Vicente, V. Understanding EMS response times: A machine-learning-based analysis. BMC Med. Inform. Decis. Mak. 2025, 25, 143. [Google Scholar] [CrossRef]
- Jafari, M.; Mahmoudian, P.; Ebrahimipour, H.; Vafaee-Nezhad, R.; Vafaee-Najar, A.; Hosseini, S.-E.; Haghighi, H. Response time and causes of delay in prehospital emergency missions in Mashhad, 2015. Med. J. Islam. Repub. Iran 2021, 35, 142. [Google Scholar] [CrossRef]
- Alchimbayeva, M.; Glushkova, N.; Mammadov, V.; Aliyeva, S.; Dyussupova, A.; Dyussupov, A.; Tsigengagel, O. The intention to disclose medical errors among health professionals in Kazakhstan. Int. J. Healthc. Manag. 2024, 17, 409–415. [Google Scholar] [CrossRef]
- Alamri, A. A smart spatial routing and accessibility analysis system for EMS using catchment areas of Voronoi spatial model and time-based Dijkstra’s routing algorithm. Int. J. Environ. Res. Public Health 2023, 20, 1808. [Google Scholar] [CrossRef]
- Azimi, A.; Bagheri, N.; Mostafavi, S.M.; Furst, M.A.; Hashtarkhani, S.; Amin, F.H.; Eslami, S.; Kiani, F.; VafaeiNezhad, R.; Akbari, T.; et al. Spatial-time analysis of cardiovascular emergency medical requests: Enlightening policy and practice. BMC Public Health 2021, 21, 7. [Google Scholar] [CrossRef]
- Kwon, H.; Kim, S.; Kim, D. Regional disparities in 119 emergency medical services response times in South Korea: A focus on Busan. Sustain. Sci. Technol. Environ. 2025, 55, 100761. [Google Scholar] [CrossRef]
- Zhu, H.; Xu, M.; Zhu, L. Measuring spatiotemporal accessibility and equity of emergency medical services in Shanghai, China. PLoS ONE 2025, 20, e0322656. [Google Scholar] [CrossRef]






| Clinical Outcome | Males, n (%) | Females, n (%) | Total, N (%) |
|---|---|---|---|
| Refusal of Hospitalization | 8529 (54.5%) | 6214 (59.7%) | 14,743 (56.5%) |
| Inpatient Admission | 7132 (45.5%) | 4198 (40.3%) | 11,330 (43.5%) |
| Total Call Volume | 15,661 (60.1%) | 10,412 (39.9%) | 26,073 (100%) |
| Statistical Significance | χ2 = 70.97, p < 0.001 |
| Service Interval | Mean (SD), min | Median (IQR), min | Benchmark Compliance (%) |
|---|---|---|---|
| Call-to-Dispatch | 6.29 (2.1) | 5.1 (4.0–7.2) | 78.1% within <5 min |
| Dispatch-to-Scene | 15.02 (4.8) | 13.8 (10.5–18.2) | 25% within <10 min |
| Call-to-Arrival (Total) | 21.63 (5.3) | 19.5 (15.2–24.1) | 16.9% within <10 min |
| Call-to-Admission | 55.78 (12.4) | 51.88 (41.7–64.2) | Target: “Golden Hour” |
| Administrative District | EMS Station Access (0–10 min) | Hospital Access (0–10 min) | Delay Rate (>10 min Travel) |
|---|---|---|---|
| Baikonur | 98.2% | 98.8% | 61.4% |
| Saryarka | 98.5% | 99.5% | 58.2% |
| Almaty | 99.1% | 99.8% | 45.1% |
| Esil | 99.6% | 99.9% | 32.7% |
| Nura | 99.8% | 99.9% | 28.4% |
| Statistical Test | Kruskal-Wallis p < 0.001 |
| Variable | Category/Comparison | Adjusted OR (aOR) | 95% CI | p-Value |
|---|---|---|---|---|
| Sex | Female vs. male | 1.12 | 1.05–1.19 | <0.001 |
| Age group | 0–17 vs. 18–39 | 1.14 | 1.07–1.23 | <0.001 |
| 40–59 vs. 18–39 | 1.10 | 1.01–1.19 | 0.026 | |
| ≥60 vs. 18–39 | 1.25 | 1.12–1.39 | <0.001 | |
| Urgency category | Category 2 vs. 1 | 7.77 | 6.84–8.82 | <0.001 |
| Category 3 vs. 1 | 40.53 | 35.97–45.68 | <0.001 | |
| Category 4 vs. 1 | 125.67 | 71.03–222.35 | <0.001 | |
| Year of call | 2021 vs. 2020 | 1.11 | 1.03–1.20 | 0.005 |
| 2022 vs. 2020 | 1.70 | 1.55–1.86 | <0.001 | |
| 2023 vs. 2020 | 1.53 | 1.41–1.66 | <0.001 | |
| 2024 vs. 2020 | 2.40 | 2.11–2.73 | <0.001 | |
| Season | Spring vs. winter | 0.89 | 0.82–0.97 | 0.006 |
| Summer vs. winter | - | - | 0.054 | |
| Autumn vs. winter | 0.86 | 0.79–0.95 | 0.002 | |
| Time of day | Morning vs. night | - | - | 0.350 |
| Afternoon vs. night | 1.21 | 1.10–1.33 | <0.001 | |
| Evening vs. night | 1.21 | 1.11–1.32 | <0.001 | |
| Day type | Weekend vs. weekday | 0.92 | 0.87–0.98 | 0.011 |
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Chayakova, A.; Tsigengagel, O. Urban Environmental Determinants and Spatiotemporal Patterns of Emergency Medical Service Response to Traumatic Injuries: A Five-Year Population-Based Study. Int. J. Environ. Res. Public Health 2026, 23, 434. https://doi.org/10.3390/ijerph23040434
Chayakova A, Tsigengagel O. Urban Environmental Determinants and Spatiotemporal Patterns of Emergency Medical Service Response to Traumatic Injuries: A Five-Year Population-Based Study. International Journal of Environmental Research and Public Health. 2026; 23(4):434. https://doi.org/10.3390/ijerph23040434
Chicago/Turabian StyleChayakova, Akerke, and Oxana Tsigengagel. 2026. "Urban Environmental Determinants and Spatiotemporal Patterns of Emergency Medical Service Response to Traumatic Injuries: A Five-Year Population-Based Study" International Journal of Environmental Research and Public Health 23, no. 4: 434. https://doi.org/10.3390/ijerph23040434
APA StyleChayakova, A., & Tsigengagel, O. (2026). Urban Environmental Determinants and Spatiotemporal Patterns of Emergency Medical Service Response to Traumatic Injuries: A Five-Year Population-Based Study. International Journal of Environmental Research and Public Health, 23(4), 434. https://doi.org/10.3390/ijerph23040434

