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Review

Human Papillomavirus: A Narrative Review for Dental Providers in Prevention and Care

1
Institute on Aging, Portland State University, Portland, OR 97201, USA
2
College of Dental Medicine, Roseman University of Health Sciences, Summerlin, NV 89135, USA
3
Portland State University, Portland, OR 97201, USA
4
Division of Public Health, University of Utah, Salt Lake City, UT 84112, USA
5
Department of Orthopaedics, University of Utah, Salt Lake City, UT 84112, USA
6
Huntsman Cancer Institute, Salt Lake City, UT 84112, USA
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2025, 22(3), 439; https://doi.org/10.3390/ijerph22030439
Submission received: 15 January 2025 / Revised: 5 March 2025 / Accepted: 12 March 2025 / Published: 17 March 2025
(This article belongs to the Special Issue Oral Diseases: Prevention, Diagnosis and Treatment)

Abstract

(1) Introduction: Human papillomavirus (HPV) is a significant public health concern associated with various cancers, including a rising incidence of oropharyngeal cancer (OPC). Despite the availability of effective vaccines targeting high-risk HPV types, vaccination rates remain suboptimal. Dental professionals are uniquely positioned to contribute to HPV prevention through education, vaccination advocacy, and early detection. (2) Methods: This narrative review synthesized the literature from 2006 to 2024 on HPV epidemiology, pathophysiology, vaccine efficacy, and the role of dental providers in HPV prevention. Sources included peer-reviewed articles listed in Pubmed and Google Scholar, including observational studies and review articles, guidelines, clinical trials, and governmental data. Key barriers to HPV-related care in dental practice and strategies for overcoming them were analyzed. (3) Results: The review underscores the critical role of dentists in HPV-related disease prevention, highlighting their ability to detect HPV-related lesions, promote vaccine uptake, and address patient concerns. Barriers such as limited knowledge, discomfort discussing HPV, and misinformation were identified. Strategies like incorporating HPV education into dental training, utilizing emerging diagnostic tools, and adopting effective communication approaches can enhance the role of dental professionals in reducing HPV-associated cancer risks. (4) Conclusion: By integrating HPV education, vaccination advocacy, and early detection into routine dental care, dental professionals can play a transformative role in public health. A dental provider’s endorsement can increase HPV vaccine uptake and help prevent oral cancer. These efforts align with broader health promotion goals, offering a significant opportunity to reduce the burden of HPV-associated cancers and improve long-term patient outcomes.
Keywords: HPV prevention; oropharyngeal cancer; dental professionals; vaccination advocacy; early detection HPV prevention; oropharyngeal cancer; dental professionals; vaccination advocacy; early detection

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MDPI and ACS Style

Lipsky, M.S.; Wolfe, G.; Radilla, B.A.; Hung, M. Human Papillomavirus: A Narrative Review for Dental Providers in Prevention and Care. Int. J. Environ. Res. Public Health 2025, 22, 439. https://doi.org/10.3390/ijerph22030439

AMA Style

Lipsky MS, Wolfe G, Radilla BA, Hung M. Human Papillomavirus: A Narrative Review for Dental Providers in Prevention and Care. International Journal of Environmental Research and Public Health. 2025; 22(3):439. https://doi.org/10.3390/ijerph22030439

Chicago/Turabian Style

Lipsky, Martin S., Geo Wolfe, Brisa A. Radilla, and Man Hung. 2025. "Human Papillomavirus: A Narrative Review for Dental Providers in Prevention and Care" International Journal of Environmental Research and Public Health 22, no. 3: 439. https://doi.org/10.3390/ijerph22030439

APA Style

Lipsky, M. S., Wolfe, G., Radilla, B. A., & Hung, M. (2025). Human Papillomavirus: A Narrative Review for Dental Providers in Prevention and Care. International Journal of Environmental Research and Public Health, 22(3), 439. https://doi.org/10.3390/ijerph22030439

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