Next Article in Journal
Diabetes Mellitus and Its Risk Factors among Migrant Workers in Kuwait
Next Article in Special Issue
The Impact of Delivering School-Based Wellness Programs for Emerging Adult Facilitators—A Quasi-Controlled Clinical Trial
Previous Article in Journal
Spatial-Temporal Evolution and Influencing Factors of Urban Green and Smart Development Level in China: Evidence from 232 Prefecture-Level Cities
Previous Article in Special Issue
Gender Stereotypes among Teachers and Trainers Working with Adolescents
 
 
Systematic Review

Interventions to Improve Treatment Outcomes among Adolescents on Antiretroviral Therapy with Unsuppressed Viral Loads: A Systematic Review

1
School of Public Health, University of the Western Cape, Cape Town 7535, South Africa
2
Department of Psychology, University of the Western Cape, Cape Town 7535, South Africa
*
Author to whom correspondence should be addressed.
Academic Editors: Paul B. Tchounwou and Maria Chironna
Int. J. Environ. Res. Public Health 2022, 19(7), 3940; https://doi.org/10.3390/ijerph19073940
Received: 17 February 2022 / Revised: 16 March 2022 / Accepted: 21 March 2022 / Published: 25 March 2022
Adolescents living with HIV (ALHIV) face unique developmental challenges that increase the risk of unsuppressed viral loads. Current reviews present a need for proven interventions to improve viral suppression among ALHIV on ART, who have a history of unsuppressed viral loads. This systematic review aims to synthesize and appraise evidence of the effectiveness of interventions to improve treatment outcomes among ALHIV with unsuppressed viral loads. Six bibliographic databases were searched for published studies and gray literature from 2010 to 2021. The risk of bias and certainty of evidence was assessed using the ROBINS-I tool, CASP checklists and GRADE. A total of 28 studies were eligible for full-text screening; and only three were included in the qualitative synthesis. In addition, two studies were included from website searches. Four types of interventions to improve viral suppression were identified, namely: intensive adherence counselling; community- and facility-based peer-led differentiated service delivery (DSD); family based economic empowerment; and conditional economic incentives and motivational interviewing. We strongly recommend peer-led community-based DSD interventions, intensive adherence counselling, and family-based economic empowerment as potential interventions to improve viral suppression among ALHIV. View Full-Text
Keywords: adolescents; HIV; antiretroviral; retention; viral suppression adolescents; HIV; antiretroviral; retention; viral suppression
Show Figures

Figure 1

MDPI and ACS Style

Munyayi, F.K.; van Wyk, B.; Mayman, Y. Interventions to Improve Treatment Outcomes among Adolescents on Antiretroviral Therapy with Unsuppressed Viral Loads: A Systematic Review. Int. J. Environ. Res. Public Health 2022, 19, 3940. https://doi.org/10.3390/ijerph19073940

AMA Style

Munyayi FK, van Wyk B, Mayman Y. Interventions to Improve Treatment Outcomes among Adolescents on Antiretroviral Therapy with Unsuppressed Viral Loads: A Systematic Review. International Journal of Environmental Research and Public Health. 2022; 19(7):3940. https://doi.org/10.3390/ijerph19073940

Chicago/Turabian Style

Munyayi, Farai Kevin, Brian van Wyk, and Yolanda Mayman. 2022. "Interventions to Improve Treatment Outcomes among Adolescents on Antiretroviral Therapy with Unsuppressed Viral Loads: A Systematic Review" International Journal of Environmental Research and Public Health 19, no. 7: 3940. https://doi.org/10.3390/ijerph19073940

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop