Regional Odontodysplasia: A Systematic Review of Case Reports
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Zegarelli, E.V.; Kutscher, A.H.; Applebaum, E.; Archard, H.O. Odontodysplasia. Oral Surg Oral Med Oral Pathol 1963, 16, 187–193. [Google Scholar] [CrossRef]
- Pandis, N.; Polido, C.; Bell, W.H. Regional Odontodysplasia. A Case Associated with Asymmetric Maxillary and Mandibular Development. Oral Surg. Oral Med. Oral Pathol. 1991, 72, 492–496. [Google Scholar] [CrossRef]
- Cahuana, A.; González, Y.; Palma, C. Clinical Management of Regional Odontodysplasia. Pediatr. Dent. 2005, 27, 34–39. [Google Scholar] [PubMed]
- Gomes, M.P.; Modesto, A.; Cardoso, A.S.; Hespanhol, W. Regional Odontodysplasia: Report of a Case Involving Two Separate Affected Areas. ASDC J. Dent. Child. 1999, 66, 155, 203–207. [Google Scholar] [PubMed]
- Mathew, A.; Dauravu, L.M.; Reddy, S.N.; Kumar, K.R.; Venkataramana, V. Ghost Teeth: Regional Odontodysplasia of Maxillary First Molar Associated with Eruption Disorders in a 10-Year-Old Girl. J. Pharm. Bioallied. Sci. 2015, 7, S800–S803. [Google Scholar] [CrossRef] [PubMed]
- Ponranjini, V.C.; Jayachandran, S.; Bakyalakshmi, K. Regional Odontodysplasia: Report of a Case. J. Dent. Child. 2012, 79, 26–29. [Google Scholar]
- Ozer, L.; Cetiner, S.; Ersoy, E. Regional Odontodysplasia: Report of a Case. J. Clin. Pediatr. Dent. 2004, 29, 45–48. [Google Scholar] [CrossRef]
- Volpato, L.; Botelho, G.; Casela, L.; Borges, A.; Silva, K. Regional Odontodysplasia: Report of a Case in the Mandible Crossing the Midline. J. Contemp. Dent. Pract. 2008, 9, 142–148. [Google Scholar] [CrossRef] [Green Version]
- Ramakrishnan, M.; Menon, P. Odontodysplasia Involving Single Tooth: A Rare Entity. SRM J. Res. Dent. Sci. 2014, 5, 140–142. [Google Scholar] [CrossRef]
- Slootweg, P.J.; Meuwissen, P.R. Regional Odontodysplasia in Epidermal Nevus Syndrome. J. Oral Pathol. 1985, 14, 256–262. [Google Scholar] [CrossRef]
- Steiman, H.R.; Cullen, C.L.; Geist, J.R. Bilateral Mandibular Regional Odontodysplasia with Vascular Nevus. Pediatr. Dent. 1991, 13, 303–306. [Google Scholar] [PubMed]
- Koskinen, S.; Keski-Filppula, R.; Alapulli, H.; Nieminen, P.; Anttonen, V. Familial Oligodontia and Regional Odontodysplasia Associated with a PAX9 Initiation Codon Mutation. Clin. Oral Investig. 2019, 23, 4107–4111. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Fujiwara, T.; Nakano, K.; Sobue, S.; Ooshima, T. Simultaneous Occurrence of Unusual Odontodysplasia and Oligodontia in the Permanent Dentition: Report of a Case. Int. J. Paediatr. Dent. 2000, 10, 341–347. [Google Scholar] [CrossRef] [PubMed]
- Jahanimoghadam, F.; Pishbin, L.; Rad, M. Clinical, Radiographic, and Histologic Evaluation of Regional Odontodysplasia: A Case Report with 5-Year Follow-Up. J. Dent. 2016, 17, 159–163. [Google Scholar]
- Nijakowski, K.; Surdacka, A. Regional Odontodysplasia—A Rare Developmental Dental Anomaly. Pediatr. Pol. 2021, 96, 153–155. [Google Scholar] [CrossRef]
- Page, M.J.; McKenzie, J.; Bossuyt, P.; Boutron, I.; Hoffmann, T.; Mulrow, C.D.; Shamseer, L.; Tetzlaff, J.; Akl, E.; Brennan, S.E.; et al. The PRISMA 2020 Statement: An Updated Guideline for Reporting Systematic Reviews. BMJ 2021, 372, n71. [Google Scholar] [CrossRef]
- OCEBM Levels of Evidence. Available online: https://www.cebm.net/2016/05/ocebm-levels-of-evidence/ (accessed on 22 August 2020).
- Crawford, P.J.; Aldred, M.J. Regional Odontodysplasia: A Bibliography. J. Oral Pathol. Med. 1989, 18, 251–263. [Google Scholar] [CrossRef]
- Tervonen, S.A.; Stratmann, U.; Mokrys, K.; Reichart, P.A. Regional Odontodysplasia: A Review of the Literature and Report of Four Cases. Clin. Oral Investig. 2004, 8, 45–51. [Google Scholar] [CrossRef]
- Alotaibi, O.; Alotaibi, G.; Alfawaz, N. Regional Odontodysplasia: An Analysis of 161 Cases from 1953 to 2017. Saudi Dent. J. 2019, 31, 306–310. [Google Scholar] [CrossRef]
- Courson, F.; Bdeoui, F.; Danan, M.; Degrange, M.; Gogly, B. Regional Odontodysplasia: Expression of Matrix Metalloproteinases and Their Natural Inhibitors. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 2003, 95, 60–66. [Google Scholar] [CrossRef]
- Carlos, R.; Contreras-Vidaurre, E.; de Almeida, O.P.; Silva, K.R.; Abrahão, P.G.; Miranda, A.M.M.A.; Pires, F.R. Regional Odontodysplasia: Morphological, Ultrastructural, and Immunohistochemical Features of the Affected Teeth, Connective Tissue, and Odontogenic Remnants. J. Dent. Child. 2008, 75, 144–150. [Google Scholar]
- Miloglu, O.; Goregen, M.; Akgul, H.M.; Harorli, A. Generalized Familial Crown Resorptions in Unerupted Teeth. Eur. J. Dent. 2011, 5, 206–209. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Clark, S.L.; Cairns, A.M.; Hunter, K.D. Comparative Case Report of Segmental Odontomaxillary Dysplasia and Regional Odontodysplasia. Dent. Update 2014, 41, 825–831. [Google Scholar] [CrossRef]
- Shah, N.; Gupta, Y.K. Generalized Odontodysplasia—A Case Report. J. Indian Soc. Pedod. Prev. Dent. 1998, 16, 40–43. [Google Scholar]
- Ibrahim Mostafa, M.; Samir Taha, N.; Ismail Mehrez, M.A. Generalised versus Regional Odontodysplasia: Diagnosis, Transitional Management, and Long-Term Followup—A Report of 2 Cases. Case Rep. Dent. 2013, 2013, 1–5. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Jensen, J.L.; Ambjornsen, E.; Haanaes, H.R.; Storhaug, K. Case Report: Unclassified Syndrome Involving Dental Enamel, Dentine and Lack of Tooth Eruption. Eur. Arch. Paediatr. Dent. 2009, 10, 244–247. [Google Scholar] [CrossRef]
- Majumdar, S.; Uppala, D.; Priyanka, K.; Kumar, S. Bilateral Regional Odontodysplasia: A Rare Case Report. Oral Maxillofac. Pathol. J. 2021, 7, 755–757. [Google Scholar]
- Koruyucu, M.; Yaman, D.; Seymen, F.; Demirel, K.; Gençay, K. Management of Regional Odontodysplasia: A 10-Year-Follow-up Case Report and Literature Review. Eur. Oral Res. 2018, 52, 111–116. [Google Scholar] [CrossRef]
- Abdel-Kader, M.A.; Abdelazeem, A.F.; Ahmed, N.E.-M.B.; Khalil, Y.M.; Mostafa, M.I. Oral Rehabilitation of a Case with Regional Odontodysplasia Using a Regenerative Approach-A Case Report and a Review of Literature. Spec. Care Dentist. 2019, 39, 330–339. [Google Scholar] [CrossRef]
- Bagherpoor, M.R.; Siadat, H.; Nokar, S.; Alikhasi, M. Step-by-Step Oral Rehabilitation of a Generalized Odontodysplastic Patient with Implant-Supported Prostheses: A Clinical Report. Implant. Dent. 2010, 19, 122–127. [Google Scholar] [CrossRef]
- Iizawa, F.; Kinjoh, N.; Taguchi, Y. Regional Odontodysplasia: Long-Term Observation of a Case on the Mandibular Left Side. Pediatric Dent. J. 2010, 20, 103–109. [Google Scholar] [CrossRef] [Green Version]
- van der Wal, J.E.; Rittersma, J.; Baart, J.A.; van der Waal, I. Regional Odontodysplasia: Report of Three Cases. Int. J. Oral Maxillofac. Surg. 1993, 22, 356–358. [Google Scholar] [CrossRef]
- von Arx, T. Autotransplantation for Treatment of Regional Odontodysplasia. Case Report with 6-Year Follow-Up. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 1998, 85, 304–307. [Google Scholar] [CrossRef]
- Ziegler, S.; Neukam, F.W. Regional Odontodysplasia: Orthodontic Treatment and Transplantation of Premolars. Am. J. Orthod. Dentofacial. Orthop. 2012, 142, 710–719. [Google Scholar] [CrossRef]
Parameter | Inclusion Criteria | Exclusion Criteria |
---|---|---|
Population | patients with regional odontodysplasia—aged from 0 to 99 years, both sexes | patients with other developmental dental anomalies |
Intervention | not applicable | |
Comparison | not applicable | |
Outcomes | clinical description with radiological features and/or histopathological analyses | only histopathological or another analysis without clinical description |
Study design | case reports | literature reviews, expert opinion, letters to editor, conference reports, case–control, cohort and cross-sectional studies |
published up to September 2021 | not published in English |
All n = 180 | Male n = 88 | Female n = 91 | p-Value | ||
---|---|---|---|---|---|
dentition | primary | 5.0 | 3.4 | 6.6 | 0.479 |
secondary | 28.9 | 29.5 | 27.5 | ||
both | 66.1 | 67.1 | 65.9 | ||
jaw | maxilla | 61.1 | 58.0 | 63.7 | 0.680 |
mandible | 30.0 | 34.0 | 26.4 | ||
both | 8.9 | 8.0 | 9.9 | ||
quadrants | 1st | 44.4 | 47.7 | 40.7 | 0.281 |
2nd | 45.6 | 37.5 | 53.8 | 0.048 * | |
3rd | 25.6 | 27.3 | 24.2 | 0.665 | |
4th | 28.9 | 26.1 | 31.9 | 0.497 | |
affected region | left side of maxilla | 25.0 | 18.2 | 31.9 | 0.362 |
right side of maxilla | 21.7 | 23.8 | 18.7 | ||
left side of mandible | 10.0 | 15.9 | 4.4 | ||
right side of mandible | 11.7 | 12.5 | 11.0 | ||
bilateral maxilla | 14.4 | 15.9 | 13.2 | ||
bilateral mandible | 8.3 | 5.7 | 11.0 | ||
ipsilateral left quadrants | 0.0 | 0.0 | 0.0 | ||
ipsilateral right quadrants | 1.7 | 2.3 | 1.1 | ||
contralateral quadrants | 0.0 | 0.0 | 0.0 | ||
without one quadrant | 1.7 | 2.3 | 1.1 | ||
generalised | 5.5 | 3.4 | 7.6 |
Clinical Features | All n = 159 | Male n = 76 | Female n = 83 | p-Value |
yellowish-brown colour | 90.6 | 89.5 | 91.6 | 0.652 |
gingival swelling | 67.3 | 55.3 | 78.3 | 0.002 * |
underdeveloped one side of maxilla/mandible | 17.6 | 21.1 | 14.5 | 0.276 |
active fistulas | 18.9 | 18.4 | 19.3 | 0.890 |
tooth mobility | 41.5 | 34.2 | 48.2 | 0.074 |
early loss of primary teeth | 47.8 | 50.0 | 45.8 | 0.595 |
delayed tooth eruption | 90.6 | 93.4 | 88.0 | 0.239 |
local pain | 44.7 | 36.8 | 51.8 | 0.058 |
Radiological features | All n= 166 | Male n= 79 | Female n= 87 | p-Value |
ghost teeth | 100 | 100 | 100 | - |
poorly developed buds | 92.2 | 91.1 | 93.1 | 0.638 |
periapical lesions | 39.2 | 40.5 | 37.9 | 0.734 |
Treatment Method | All n = 159 | Male n = 75 | Female n = 83 | p-Value |
---|---|---|---|---|
conservative restoration | 14.5 | 18.7 | 10.8 | 0.164 |
steel crown | 5.7 | 8.0 | 3.6 | 0.235 |
pulpotomy/RCT | 2.5 | 4.0 | 1.2 | 0.264 |
tooth extraction | 78.6 | 74.7 | 83.1 | 0.191 |
acrylic partial denture | 34.6 | 40.0 | 30.1 | 0.193 |
orthodontic treatment | 16.4 | 21.3 | 12.0 | 0.116 |
implantoprosthetic treatment | 7.5 | 6.7 | 8.4 | 0.676 |
autotransplantation | 1.9 | 1.3 | 2.4 | 0.621 |
Histopathological Features | n = 80 |
---|---|
hypoplastic and hypomineralised enamel | 77.5 |
irregular calcification of dentin | 92.5 |
irregular dentino–enamel junction | 28.8 |
pulpal calcifications | 45.0 |
dislocated cementum | 8.8 |
Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. |
© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Share and Cite
Nijakowski, K.; Woś, P.; Surdacka, A. Regional Odontodysplasia: A Systematic Review of Case Reports. Int. J. Environ. Res. Public Health 2022, 19, 1683. https://doi.org/10.3390/ijerph19031683
Nijakowski K, Woś P, Surdacka A. Regional Odontodysplasia: A Systematic Review of Case Reports. International Journal of Environmental Research and Public Health. 2022; 19(3):1683. https://doi.org/10.3390/ijerph19031683
Chicago/Turabian StyleNijakowski, Kacper, Patryk Woś, and Anna Surdacka. 2022. "Regional Odontodysplasia: A Systematic Review of Case Reports" International Journal of Environmental Research and Public Health 19, no. 3: 1683. https://doi.org/10.3390/ijerph19031683