Are Healthcare Workers Infected with SARS-CoV-2 at Home or at Work? A Comparative Prevalence Study
Abstract
:1. Introduction
2. Methods
3. Results
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Centers for Disease Control and Prevention–CDC. Coronavirus Disease 2019 (COVID-19) in the U.S. [Internet]. Centers for Disease Control and Prevention. 2020. Available online: https://www.cdc.gov/covid-data-tracker (accessed on 31 October 2020).
- Lai, X.; Wang, M.; Qin, C.; Tan, L.; Ran, L.; Chen, D.; Zhang, H.; Shang, K.; Xia, C.; Wang, S.; et al. Coronavirus Disease 2019 (COVID-2019) Infection Among Health Care Workers and Implications for Prevention Measures in a Tertiary Hospital in Wuhan, China. JAMA Netw. Open 2020, 3, e209666. [Google Scholar] [CrossRef]
- Khalil, A.; Hill, R.; Ladhani, S.; Pattisson, K.; O’Brien, P. COVID-19 screening of health-care workers in a London maternity hospital. Lancet Infect. Dis. 2020, 21, 23–24. [Google Scholar] [CrossRef]
- Houlihan, C.F.; Vora, N.; Byrne, T.; Lewer, D.; Kelly, G.; Heaney, J.; Gandhi, S.; Spyer, M.J.; Beale, R.; Cherepanov, P.; et al. Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers. Lancet 2020, 396, e6–e7. [Google Scholar] [CrossRef]
- Spalanzani, R.N.; Genelhoud, G.; Raboni, S.M.; de Almeida, S.M.; Pereira, L.A.; Rotta, I.; Cavalli, B.M.; Moreira, F.B.; Dino, C.L.T.; Takahashi, G.R.D.A.; et al. Severe acute respiratory syndrome coronavirus 2 infection among healthcare workers in a tertiary public hospital in Curitiba, Brazil. Rev. Soc. Bras. Med. Trop. 2022, 55, e0265. [Google Scholar] [CrossRef]
- Lombardi, A.; Consonni, D.; Carugno, M.; Bozzi, G.; Mangioni, D.; Muscatello, A.; Castelli, V.; Palomba, E.; Cantù, A.P.; Ceriotti, F.; et al. Characteristics of 1573 health-care workers who underwent nasopharyngeal swab testing for SARS-CoV-2 in Milan, Lombardy, Italy. Clin. Microbiol. Infect. 2020, 26, 1413.E9–1413.E13. [Google Scholar] [CrossRef] [PubMed]
- Kambhampati, A.K.; O’Halloran, A.C.; Whitaker, M.; Magill, S.S.; Chea, N.; Chai, S.J.; Kirley, P.D.; Herlihy, R.K.; Kawasaki, B.; Meek, J.; et al. COVID-19–Associated Hospitalizations Among Health Care Personnel–COVID-NET, 13 States, March 1–May 31, 2020. MMWR. Morb. Mortal. Wkly. Rep. 2020, 69, 1576–1583. [Google Scholar] [CrossRef]
- Verbeek, J.H.; Rajamaki, B.; Ijaz, S.; Sauni, R.; Toomey, E.; Blackwood, B.; Tikka, C.; Ruotsalainen, J.H.; Balci, F.S.K. Personal protective equipment for preventing highly infectious diseases due to exposure to contaminated body fluids in healthcare staff. Cochrane Database Syst. Rev. 2020, 2020, CD011621. [Google Scholar] [CrossRef]
- Nguyen, L.H.; Drew, D.A.; Graham, M.S.; Joshi, A.D.; Guo, C.-G.; Ma, W.; Mehta, R.S.; Warner, E.T.; Sikavi, D.R.; Lo, C.-H.; et al. Risk of COVID-19 among front-line health-care workers and the general community: A prospective cohort study. Lancet Public Health 2020, 5, e475–e483. [Google Scholar] [CrossRef]
- Liu, M.; Cheng, S.-Z.; Xu, K.-W.; Yang, Y.; Zhu, Q.-T.; Zhang, H.; Yang, D.-Y.; Cheng, S.-Y.; Xiao, H.; Wang, J.-W.; et al. Use of personal protective equipment against coronavirus disease 2019 by healthcare professionals in Wuhan, China: Cross sectional study. BMJ 2020, 369, m2195. [Google Scholar] [CrossRef]
- Ministry of Health, Israel. COVID-19 Dashboard. (In Hebrew). [Internet]. 2020. Available online: https://datadashboard.health.gov.il/COVID-19/general?utm_source=go.gov.il&utm_medium=referral (accessed on 31 October 2020).
- Rimmer, A. COVID-19: Two thirds of healthcare workers who have died were from ethnic minorities. BMJ 2020, 369, m1621. [Google Scholar] [CrossRef] [PubMed]
- Birenbaum-Carmeli, D.; Chassida, J. COVID-19 in Israel: Socio-demographic characteristics of first wave morbidity in Jewish and Arab communities. Int. J. Equity Health 2020, 19, 1–13. [Google Scholar] [CrossRef]
- Stein-Zamir, C.; Levine, H. The measles outbreak in Israel in 2018-19: Lessons for COVID-19 pandemic. Hum. Vaccines Immunother. 2021, 17, 2085–2089. [Google Scholar] [CrossRef] [PubMed]
- Korach, M.; Coshen, M. Jerusalem facts and trends, 2021. Jerusalem Institute for Policy Research. 2021. Available online: https://jerusaleminstitute.org.il/wp-content/uploads/2021/05/Pub_564_facts_and_trends_2021_eng.pdf (accessed on 1 June 2022).
- Ministry of Health, Israel. COVID-19 among Hospital Workers. (In Hebrew). [Internet]. Available online: https://data.gov.il/dataset/covid-19/resource/6253ce68-5f31-4381-bb4e-557260d5c9fc (accessed on 15 November 2020).
- Temkin, E.; Schwaber, M.J.; Solter, E.; Vaturi, A.; Hen, D.; Lugassy, C.G.; Teitler, N.; Nutman, A.; Rubinovitch, B.; Ben-Zvi, H.; et al. Extremely low prevalence of asymptomatic COVID-19 among healthcare workers caring for COVID-19 patients in Israeli hospitals: A cross-sectional study. Clin. Microbiol. Infect. 2020, 27, 130.e1–130.e4. [Google Scholar] [CrossRef] [PubMed]
- Oster, Y.; Wolf, D.G.; Olshtain-Pops, K.; Rotstein, Z.; Schwartz, C.; Benenson, S. Proactive screening approach for SARS-CoV-2 among healthcare workers. Clin. Microbiol. Infect. 2020, 27, 155–156. [Google Scholar] [CrossRef]
- Schwartz, C.; Oster, Y.; Slama, C.; Benenson, S.; Cohen, A.; Favor, A.; Gross, I.; Luski, S.; Ottolenghi, M.; Parnasa, E.; et al. A dynamic response to exposures of healthcare workers to newly diagnosed COVID-19 patients or hospital personnel, in order to minimize cross transmission and need for suspension from work during the outbreak. Open Forum Infect. Dis. 2020, 7, ofaa384. [Google Scholar] [CrossRef] [PubMed]
- Barak, N.; Ben-Ami, R.; Sido, T.; Perri, A.; Shtoyer, A.; Rivkin, M.; Licht, T.; Peretz, A.; Magenheim, J.; Fogel, I.; et al. Lessons from applied large-scale pooling of 133,816 SARS-CoV-2 RT-PCR tests. Sci. Transl. Med. 2021, 13, eabf2823. [Google Scholar] [CrossRef] [PubMed]
- Bandyopadhyay, S.; Baticulon, R.E.; Kadhum, M.; Alser, M.; Ojuka, D.K.; Badereddin, Y.; Kamath, A.; Parepalli, S.A.; Brown, G.; Iharchane, S.; et al. Infection and mortality of healthcare workers worldwide from COVID-19: A systematic review. BMJ Glob. Health 2020, 5, e003097. [Google Scholar] [CrossRef] [PubMed]
- Koh, D.; Goh, H.P. Occupational health responses to COVID-19: What lessons can we learn from SARS? J. Occup. Health 2020, 62, e12128. [Google Scholar] [CrossRef] [PubMed]
- Erdem, H.; Lucey, D.R. Healthcare worker infections and deaths due to COVID-19: A survey from 37 nations and a call for WHO to post national data on their website. Int. J. Infect. Dis. 2021, 102, 239–241. [Google Scholar] [CrossRef]
- Gómez-Ochoa, S.A.; Franco, O.H.; Rojas, L.Z.; Raguindin, P.F.; Roa-Díaz, Z.M.; Wyssmann, B.M.; Guevara, S.L.R.; Echeverría, L.E.; Glisic, M.; Muka, T. COVID-19 in Healthcare Workers: A Living Systematic Review and Meta-analysis of Prevalence, Risk Factors, Clinical Characteristics, and Outcomes. Am. J. Epidemiol. 2020, 190, 161–175. [Google Scholar] [CrossRef] [PubMed]
- Çelebi, G.; Pişkin, N.; Bekleviç, A.C.; Altunay, Y.; Keleş, A.S.; Tüz, M.A.; Altınsoy, B.; Hacıseyitoğlu, D. Specific risk factors for SARS-CoV-2 transmission among health care workers in a university hospital. Am. J. Infect. Control. 2020, 48, 1225–1230. [Google Scholar] [CrossRef] [PubMed]
- Ran, L.; Chen, X.; Wang, Y.; Wu, W.; Zhang, L.; Tan, X. Risk Factors of Healthcare Workers with Coronavirus Disease 2019: A Retrospective Cohort Study in a Designated Hospital of Wuhan in China. Clin. Infect. Dis. 2020, 71, 2218–2221. [Google Scholar] [CrossRef] [Green Version]
- Kim, J.K.; Crimmins, E.M. How does age affect personal and social reactions to COVID-19: Results from the national Understanding America Study. PLoS ONE 2020, 15, e0241950. [Google Scholar] [CrossRef]
- Wang, X.; Pan, Z.; Cheng, Z. Association between 2019-nCoV transmission and N95 respirator use. J. Hosp. Infect. 2020, 105, 104–105. [Google Scholar] [CrossRef] [Green Version]
- La Torre, G.; Marte, M.; Previte, C.M.; Barone, L.C.; Picchioni, F.; Chiappetta, M.; Faticoni, A.; Marotta, D.; Mazzalai, E.; Barletta, V.I.; et al. The Synergistic Effect of Time of Exposure, Distance and No Use of Personal Protective Equipment in the Determination of SARS-CoV-2 Infection: Results of a Contact Tracing Follow-Up Study in Healthcare Workers. Int. J. Environ. Res. Public Health 2021, 18, 9456. [Google Scholar] [CrossRef]
- Schneider, S.; Piening, B.; Nouri-Pasovsky, P.A.; Krüger, A.C.; Gastmeier, P.; Aghdassi, S.J.S. SARS-Coronavirus-2 cases in healthcare workers may not regularly originate from patient care: Lessons from a university hospital on the underestimated risk of healthcare worker to healthcare worker transmission. Antimicrob. Resist. Infect. Control 2020, 9, 1–7. [Google Scholar] [CrossRef]
- Kirby, T. Evidence mounts on the disproportionate effect of COVID-19 on ethnic minorities. Lancet Respir. Med. 2020, 8, 547–548. [Google Scholar] [CrossRef]
- Birenbaum-Carmeli, D.; Chassida, J. Health and socio-demographic implications of the COVID-19 second pandemic wave in Israel, compared with the first wave. Int. J. Equity Health 2021, 20, 154. [Google Scholar] [CrossRef]
- Waitzberg, R.; Davidovitch, N.; Leibner, G.; Penn, N.; Brammli-Greenberg, S. Israel’s response to the COVID-19 pandemic: Tailoring measures for vulnerable cultural minority populations. Int. J. Equity Health 2020, 19, 1–5. [Google Scholar] [CrossRef] [PubMed]
- Smith, L.E.; Potts, H.W.W.; Amlȏt, R.; Fear, N.T.; Michie, S.; Rubin, G.J. Holding a stigmatizing attitude at the start of the COVID-19 outbreak: A cross-sectional survey. Br. J. Health Psychol. 2021, 27, 588–604. [Google Scholar] [CrossRef] [PubMed]
- Jacob, J.T.; Baker, J.M.; Fridkin, S.K.; Lopman, B.A.; Steinberg, J.P.; Christenson, R.H.; King, B.; Leekha, S.; O’Hara, L.M.; Rock, P.; et al. Risk Factors Associated with SARS-CoV-2 Seropositivity Among US Health Care Personnel. JAMA Netw. Open 2021, 4, e211283. [Google Scholar] [CrossRef] [PubMed]
Age Groups | |||
Age Group, years | Positive Cases, N (%) a | ||
18–26 | 95 (16.4%) | ||
27–35 | 204 (35.2%) | ||
36–44 | 90 (15.5%) | ||
45–53 | 87 (15.0%) | ||
54–62 | 63 (10.9%) | ||
63–71 | 22 (3.8%) | ||
Not specified | 18 (3.1%) | ||
Work Sectors | |||
Sector | Positive Cases, N (% of total staff) | Positive Cases, N (% of total cases) | |
All | 579/7760 (7.5%) | 579 (100.0%) | |
Medical | 80/1432 (5.5%) | 80/579 (13.8%) | |
Nursing | 205/2250 (9.1%) | 205/579 (35.4%) | |
Paramedical | 27/384 (7.0%) | 27/579 (4.6%) | |
Administrative | 267/3694 (7.2%) | 267/579 (46.1%) | |
Source of Infection according to epidemiologic investigation | |||
Hospital Acquired | 60/579 (10.3%) | ||
Community Acquired | 123/579 (21.2%) | ||
Unknown | 396/579 (68.3%) | ||
Ethnic subgroups in healthcare workers residing in Jerusalem | |||
Positive cases out of subgroup, N (%) | Positive out of total positive workers N (%) | Total Number of Workers N (%) | |
Total | 317/4470 (7.0%) | 317 (100.0%) | 4470 (100.0%) |
Jewish | 164/3256 (5.0%) | 164/317 (51.7%) | 3256/4470 (72.8%) |
Arab | 131/914 (14.3%) | 131/317 (41.3%) | 914/4470 (20.4%) |
Ultra-Orthodox Jewish | 22/300 (7.3%) | 22/317 (6.9%) | 300/4470 (6.7%) |
Positive Cases N (%) | Total Population | % Positivity | |
---|---|---|---|
Total Population (Including Children) | |||
Total population | 51,909 (100.0%) | 1,020,688 (100.0%) | 5.0% |
Jewish (%) | 11,034 (21.2%) | 366,446 (35.9%) | 3.0% |
Arab (%) | 14,303 (27.5%) | 372,750 (36.5%) | 3.8% |
Ultra-Orthodox Jewish (%) | 22,084 (42.5%) | 277,317 (27.1%) | 7.9% |
Adult Population (Above 18 Years Only) | |||
Total adult population | 24,529 (100.0%) | 605,426 (100.0%) | 4.0% |
Jewish (%) | 5829 (23.7%) | 247,212 (40.8%) | 2.3% |
Arab (%) | 8164 (33.2%) | 203,309 (33.5%) | 4.0% |
Ultra-Orthodox Jewish (%) | 10,536 (42.9%) | 154,905 (25.5%) | 6.8% |
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Zahran, S.; Nir-Paz, R.; Paltiel, O.; Stein-Zamir, C.; Oster, Y. Are Healthcare Workers Infected with SARS-CoV-2 at Home or at Work? A Comparative Prevalence Study. Int. J. Environ. Res. Public Health 2022, 19, 12951. https://doi.org/10.3390/ijerph191912951
Zahran S, Nir-Paz R, Paltiel O, Stein-Zamir C, Oster Y. Are Healthcare Workers Infected with SARS-CoV-2 at Home or at Work? A Comparative Prevalence Study. International Journal of Environmental Research and Public Health. 2022; 19(19):12951. https://doi.org/10.3390/ijerph191912951
Chicago/Turabian StyleZahran, Shadi, Ran Nir-Paz, Ora Paltiel, Chen Stein-Zamir, and Yonatan Oster. 2022. "Are Healthcare Workers Infected with SARS-CoV-2 at Home or at Work? A Comparative Prevalence Study" International Journal of Environmental Research and Public Health 19, no. 19: 12951. https://doi.org/10.3390/ijerph191912951