Exercise Capacity and Physical Activity in Non-Cystic Fibrosis Bronchiectasis after a Pulmonary Rehabilitation Home-Based Programme: A Randomised Controlled Trial
Abstract
:1. Introduction
2. Materials and Methods
2.1. Design
2.2. Participants
2.2.1. Intervention
2.2.2. Strength Training
2.2.3. Endurance Training
2.2.4. Measurement of Variables
2.3. Statistical Analysis
3. Results
3.1. Dyspnoea
3.2. Six-Minute Walk Test
3.3. Cardiopulmonary Exercise Test
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Groups | p | ||
---|---|---|---|
CG (n = 15) | IG (n = 16) | ||
Aetiology | |||
Post-infection | 4 (26.66%) | 6 (37.50%) | 0.61 1 |
Idiopathic | 4 (26.66%) | 1 (6.25%) | |
Rheumatoid arthritis | 1 (6.6%) | 2 (12.50%) | |
Immunodeficiencies | 1 (6.6%) | 1 (6.25%) | |
PCD * | 1 (6.6%) | 1 (6.25%) | |
Post-measles | 1 (6.6%) | 2 (12.50%) | |
Sarcoidosis | 1 (6.6%) | 1 (6.25%) | |
ABPA ** | 1 (6.6%) | 1 (6.22%) | |
Others | 1 (6.6%) | 1 (6.25%) | |
General characteristics | |||
Women | 10 (66.66%) | 13 (81.25%) | 0.30 1 |
Age | 59.43 ± 93.00 | 63 ± 6.14 | 0.33 2 |
BMI | 25.05 ± 2.52 | 26.35 ± 3.6 | 0.86 2 |
Smoker | 1 (6.66%) | 2 (12.50%) | 0.47 2 |
Former smoker | 2 (13.33%) | 4 (25.00%) | 0.29 2 |
Never smoker | 12 (80.00%) | 10 (62.50%) | 0.16 2 |
PYI | 2.70 ± 2.11 | 3.20 ± 1.83 | 0.45 2 |
P. Aeruginosa | 5 (33.33%) | 6 (37.50%) | 0.10 2 |
Dyspnoea | 2.07 ± 0.71 | 2.19 ± 0.63 | 0.28 2 |
E-FACED | 3.33 ± 1.73 | 3.44 ± 1.91 | 0.56 1 |
Mild | 7 (46.67%) | 8 (50.00%) | 0.54 1 |
Moderate | 7 (46.67%) | 6 (37.50%) | |
Severe | 1 (6.66%) | 2(12.50%) | |
Lung function | |||
FEV1 L | 1.84 ± 0.52 | 1.61 ± 0.44 | 0.56 1 |
FEV1% | 75.41 ± 28.44 | 71.88 ± 20.72 | 0.83 1 |
FVC L | 2.43 ± 0.71 | 2.17 ± 0.61 | 0.26 1 |
FVC% | 79.13 ± 24.14 | 79.13 ± 22.00 | 0.99 1 |
FEV1/FVC | 69.92 ± 14.73 | 74.33 ± 10.74 | 0.34 1 |
Control Group | Intervention Group | |||||
---|---|---|---|---|---|---|
Before | After | p | Before | After | p | |
Men ± SD | Mean ± SD | Mean ± SD | Mean ± SD | |||
6MWT | ||||||
Walking distance (m) | 398.87 ± 67.10 | 433.13 ± 75.88 | 0.98 1 | 401.2 ± 71.60 | 451.19 ± 67.99 | 0.006 1 |
SpO2 (%) | 95.4 ± 2.91 | 94.2 ± 3.24 | 0.42 1 | 95.4 ± 2.93 | 95.8 ± 3.20 | 0.34 1 |
Borg Scale | 1.82 ± 2.3 | 2.33 ± 3.2 | 0.38 2 | 2.45 ± 3.8 | 2.88 ± 1.31 | 0.30 2 |
Physical activity | ||||||
Total steps per day (steps) | 4.793 ± 3.236 | 4.824 ± 3.113 | 0.94 1 | 4.578 ± 3.424 | 6.591 ± 3.482 | 0.007 1 |
METS * | 1.4 ± 0.3 | 1.26 ± 0.36 | 0.15 1 | 1.42 ± 0.35 | 1.57 ± 0.35 | 0.47 1 |
Lying time | 9.03 ± 1.42 | 8.52 ± 1.02 | 0.01 1 | 8.86 ± 1.44 | 7.91 ± 1.17 | 0.02 1 |
Sleep time (hour) | 6.79 ± 1.37 | 6.73 ± 0.9 | 0.03 1 | 6.55 ± 1.06 | 6.85 ± 1.01 | 0.23 2 |
Wearing time (hour) | 22.34 ± 2.58 | 22.64 ± 1.85 | 0.75 1 | 23.32 ± 0.28 | 22.85 ± 1.71 | 0.22 1 |
Dyspnoea (mMRC) | 2.07 ± 0.70 | 2.13 ± 0.64 | 0.06 | 2.19 ± 0.57 | 1.72 ± 0.05 | 0.04 1 |
Control Group | Intervention Group | |||||
---|---|---|---|---|---|---|
Before | After | p | Before | After | p | |
Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | |||
W peak (%) | 62.7 ± 21.46 | 63.1 ± 17.34 | 0.242 | 67.2 ± 16.3 | 67.4 ± 11.9 | 0.92 1 |
VO2 max (mL/min/kg) | 13 ± 2.9 | 13.3 ± 3.4 | 0.57 1 | 14.4 ± 3.2 | 14.9 ± 3.0 | 0.17 1 |
VO2 peak (%) | 59.8 ± 14.6 | 62.2 ± 14.14 | 0.30 1 | 62.9 ± 15.8 | 66.8 ± 15.5 | 0.001 2 |
HR (bpm) | 117.13 ± 13.88 | 102.87 ± 29.04 | 0.041 | 116.25 ± 14.31 | 123.69 ± 20.5 | 0.051 |
HR(%) | 73.6 ± 8.1 | 61.3 ± 26.9 | 0.22 2 | 68.4 ± 10.1 | 61.7 ± 20.5 | 0.49 2 |
O2/HR(%) | 79.2 ± 12.2 | 81 ± 16.9 | 0.59 1 | 83.4 ± 15.8 | 83.4 ± 15.8 | 0.51 1 |
VE Max (L/min) | 34.5 ± 7.2 | 33.5 ± 11.2 | 0.65 1 | 39.8 ± 16.6 | 41.5 ± 18.4 | 0.46 1 |
EqCO2 | 31.2 ± 3.0 | 31.5 ± 4.5 | 0.73 2 | 32.4 ± 4.6 | 32.1 ± 4.1 | 0.37 2 |
RER | 0.99 ± 0.1 | 0.92 ± 0.1 | 0.09 1 | 1.03 ± 0.01 | 1.01 ± 0.1 | 0.19 1 |
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Cedeño de Jesús, S.; Almadana Pacheco, V.; Valido Morales, A.; Muñíz Rodríguez, A.M.; Ayerbe García, R.; Arnedillo-Muñoz, A. Exercise Capacity and Physical Activity in Non-Cystic Fibrosis Bronchiectasis after a Pulmonary Rehabilitation Home-Based Programme: A Randomised Controlled Trial. Int. J. Environ. Res. Public Health 2022, 19, 11039. https://doi.org/10.3390/ijerph191711039
Cedeño de Jesús S, Almadana Pacheco V, Valido Morales A, Muñíz Rodríguez AM, Ayerbe García R, Arnedillo-Muñoz A. Exercise Capacity and Physical Activity in Non-Cystic Fibrosis Bronchiectasis after a Pulmonary Rehabilitation Home-Based Programme: A Randomised Controlled Trial. International Journal of Environmental Research and Public Health. 2022; 19(17):11039. https://doi.org/10.3390/ijerph191711039
Chicago/Turabian StyleCedeño de Jesús, Sindy, Virginia Almadana Pacheco, Agustín Valido Morales, Ana Miriam Muñíz Rodríguez, Rut Ayerbe García, and Aurelio Arnedillo-Muñoz. 2022. "Exercise Capacity and Physical Activity in Non-Cystic Fibrosis Bronchiectasis after a Pulmonary Rehabilitation Home-Based Programme: A Randomised Controlled Trial" International Journal of Environmental Research and Public Health 19, no. 17: 11039. https://doi.org/10.3390/ijerph191711039