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Association of Air Pollutants with Incident Chronic Kidney Disease in a Nationally Representative Cohort of Korean Adults

1
School of Health and Environmental Science, Korea University, Seoul 02841, Korea
2
Department of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea
3
Department of Medicine, Seoul National University College of Medicine, Seoul 03080, Korea
4
Department of Family Medicine, Seoul National University Hospital, Seoul 03080, Korea
5
Department of Family Medicine, Korea University Guro Hospital, Seoul 08308, Korea
*
Author to whom correspondence should be addressed.
Academic Editor: Paul B. Tchounwou
Int. J. Environ. Res. Public Health 2021, 18(7), 3775; https://doi.org/10.3390/ijerph18073775
Received: 5 March 2021 / Revised: 31 March 2021 / Accepted: 1 April 2021 / Published: 4 April 2021
(1) Background: There is limited information regarding association between long-term exposure to air pollutants and risk of chronic kidney disease (CKD) (2). Methods: This study acquired data of 164,093 adults aged at least 40 years who were residing in 7 metropolitan cities between 2002 and 2005 from the Korean National Health Insurance Service National Sample Cohort database. CKD risk was evaluated using the multivariate Cox hazards proportional regression. All participants were followed up with until CKD, death, or 31 December 2013, whichever occurred earliest. (3) Results: Among 1,259,461 person-years of follow-up investigation, CKD cases occurred in 1494 participants. Air pollutant exposures including PM10, SO2, NO2, CO, and O3 showed no significant association with incident CKD after adjustments for age, sex, household income, area of residence, and the Charlson comorbidity index. The results were consistent in the sensitivity analyses including first and last year annual exposure analyses as well as latent periods-washed-out analyses. (4) Conclusions: Long-term exposure to air pollution is not likely to increase the risk of CKD. View Full-Text
Keywords: particulate matter; renal failure; air pollution; ozone; cohort study particulate matter; renal failure; air pollution; ozone; cohort study
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MDPI and ACS Style

Hwang, S.Y.; Jeong, S.; Choi, S.; Kim, D.H.; Kim, S.R.; Lee, G.; Son, J.S.; Park, S.M. Association of Air Pollutants with Incident Chronic Kidney Disease in a Nationally Representative Cohort of Korean Adults. Int. J. Environ. Res. Public Health 2021, 18, 3775. https://doi.org/10.3390/ijerph18073775

AMA Style

Hwang SY, Jeong S, Choi S, Kim DH, Kim SR, Lee G, Son JS, Park SM. Association of Air Pollutants with Incident Chronic Kidney Disease in a Nationally Representative Cohort of Korean Adults. International Journal of Environmental Research and Public Health. 2021; 18(7):3775. https://doi.org/10.3390/ijerph18073775

Chicago/Turabian Style

Hwang, Seo Y.; Jeong, Seogsong; Choi, Seulggie; Kim, Dong H.; Kim, Seong R.; Lee, Gyeongsil; Son, Joung S.; Park, Sang M. 2021. "Association of Air Pollutants with Incident Chronic Kidney Disease in a Nationally Representative Cohort of Korean Adults" Int. J. Environ. Res. Public Health 18, no. 7: 3775. https://doi.org/10.3390/ijerph18073775

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