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Case Report

Application of the Unified Protocol for a Japanese Patient with Post-Traumatic Stress Disorder and Multiple Comorbidities: A Single-Case Study

1
Department of Neuropsychiatry, Keio University School of Medicine, Tokyo 160-8582, Japan
2
National Center for Cognitive Behavior Therapy and Research, National Center of Neurology and Psychiatry, Tokyo 187-8551, Japan
3
National Hospital Organization Disaster Medical Center, Department of Psychiatry, Tokyo 190-0014, Japan
4
Ono Institute for Cognitive Behavior Therapy, Tokyo 102-0072, Japan
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2021, 18(21), 11644; https://doi.org/10.3390/ijerph182111644
Submission received: 30 September 2021 / Revised: 1 November 2021 / Accepted: 2 November 2021 / Published: 5 November 2021

Abstract

(1) Background: The efficacy of the Unified Protocol (UP), a transdiagnostic cognitive-behavioral therapy, with trauma-focused exposure has not been sufficiently demonstrated for post-traumatic stress disorder (PTSD) with multiple comorbidities. This study examined the effects of UP treatment with trauma-focused exposure on symptoms of PTSD and comorbidities in a client who was hesitant about exposure. (2) Methods: The client, who had comorbid dysthymia, social anxiety disorder, agoraphobia, and bulimia nervosa, participated in the UP for 20 sessions over 6 months. The principal diagnosis and symptoms of the comorbid disorders were assessed at baseline, post-intervention, and at the 3-month follow-up. This treatment was conducted as part of a clinical study (UMIN000008322). (3) Results: The client showed improvement in the principal diagnosis and symptoms of the comorbid disorders post-intervention compared with baseline and no longer met the diagnostic criteria for any of the disorders. Considerable symptom improvement was observed with imaginal exposure to trauma memories. (4) Conclusions: The UP was an effective alternative treatment for PTSD and symptoms of comorbidities in this client who was hesitant about exposure to traumatic memories, and that the inclusion of trauma-focused exposure provided sufficient therapeutic effects. Further research is needed to examine the generalizability of our findings.
Keywords: Unified Protocol; posttraumatic stress disorder; cognitive behavioral therapy; transdiagnostic intervention; emotional disorders Unified Protocol; posttraumatic stress disorder; cognitive behavioral therapy; transdiagnostic intervention; emotional disorders

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MDPI and ACS Style

Kato, N.; Ito, M.; Matsuoka, Y.J.; Horikoshi, M.; Ono, Y. Application of the Unified Protocol for a Japanese Patient with Post-Traumatic Stress Disorder and Multiple Comorbidities: A Single-Case Study. Int. J. Environ. Res. Public Health 2021, 18, 11644. https://doi.org/10.3390/ijerph182111644

AMA Style

Kato N, Ito M, Matsuoka YJ, Horikoshi M, Ono Y. Application of the Unified Protocol for a Japanese Patient with Post-Traumatic Stress Disorder and Multiple Comorbidities: A Single-Case Study. International Journal of Environmental Research and Public Health. 2021; 18(21):11644. https://doi.org/10.3390/ijerph182111644

Chicago/Turabian Style

Kato, Noriko, Masaya Ito, Yutaka J. Matsuoka, Masaru Horikoshi, and Yutaka Ono. 2021. "Application of the Unified Protocol for a Japanese Patient with Post-Traumatic Stress Disorder and Multiple Comorbidities: A Single-Case Study" International Journal of Environmental Research and Public Health 18, no. 21: 11644. https://doi.org/10.3390/ijerph182111644

APA Style

Kato, N., Ito, M., Matsuoka, Y. J., Horikoshi, M., & Ono, Y. (2021). Application of the Unified Protocol for a Japanese Patient with Post-Traumatic Stress Disorder and Multiple Comorbidities: A Single-Case Study. International Journal of Environmental Research and Public Health, 18(21), 11644. https://doi.org/10.3390/ijerph182111644

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