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Review

Effects of Dietary Red Raspberry Consumption on Pre-Diabetes and Type 2 Diabetes Mellitus Parameters

Department of Food Science and Nutrition, California Polytechnic State University, 1 Grand Avenue, San Luis Obispo, CA 93407, USA
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Author to whom correspondence should be addressed.
Academic Editor: Giuseppe Grosso
Int. J. Environ. Res. Public Health 2021, 18(17), 9364; https://doi.org/10.3390/ijerph18179364
Received: 10 July 2021 / Revised: 30 August 2021 / Accepted: 1 September 2021 / Published: 4 September 2021
Type 2 diabetes mellitus (T2DM) is a chronic metabolic condition characterized by glucose clearance abnormalities and insufficient insulin response. Left uncontrolled, T2DM can result in serious complications and death. With no cure available currently and the prevalence of major risk factors such as pre-diabetes and the metabolic syndrome continuously increasing, there is an urgent need for effective treatments with limited or no side effects. Red raspberries (RR) contain various phytonutrients with potential for modulating insulin function, glucose, and lipid metabolism. The objective of this literature review was to investigate the potential metabolic benefits of dietary RR in individuals with T2DM and pre-diabetes. A search of major scientific databases was employed to identify peer-reviewed, in vivo, or human studies that utilized whole RR or its functional constituents as treatment. The studies examined provide evidence that RR may offer clinically beneficial effects for the prevention and management of chronic diseases through improvements in glucose handling and insulin sensitivity, adiposity, lipid profiles, ectopic lipid accumulation, inflammation, oxidative stress, and cardiac health. More human trials and in vivo studies are needed to confirm the benefits of dietary RR in T2DM and pre-diabetes and to explore the dose-dependent relationships, optimal duration, and treatment modality. View Full-Text
Keywords: red raspberries; western diet; type 2 diabetes mellitus; pre-diabetes; metabolic syndrome red raspberries; western diet; type 2 diabetes mellitus; pre-diabetes; metabolic syndrome
MDPI and ACS Style

Derrick, S.A.; Kristo, A.S.; Reaves, S.K.; Sikalidis, A.K. Effects of Dietary Red Raspberry Consumption on Pre-Diabetes and Type 2 Diabetes Mellitus Parameters. Int. J. Environ. Res. Public Health 2021, 18, 9364. https://doi.org/10.3390/ijerph18179364

AMA Style

Derrick SA, Kristo AS, Reaves SK, Sikalidis AK. Effects of Dietary Red Raspberry Consumption on Pre-Diabetes and Type 2 Diabetes Mellitus Parameters. International Journal of Environmental Research and Public Health. 2021; 18(17):9364. https://doi.org/10.3390/ijerph18179364

Chicago/Turabian Style

Derrick, Stefani A., Aleksandra S. Kristo, Scott K. Reaves, and Angelos K. Sikalidis 2021. "Effects of Dietary Red Raspberry Consumption on Pre-Diabetes and Type 2 Diabetes Mellitus Parameters" International Journal of Environmental Research and Public Health 18, no. 17: 9364. https://doi.org/10.3390/ijerph18179364

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