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Article

Effects of Functional Training on Sarcopenia in Elderly Women in the Presence or Absence of ACE Inhibitors

1
Institute of Sport Sciences, University of Debrecen, 4032 Debrecen, Hungary
2
Department of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary
3
Institute of Healthcare Industry, University of Debrecen, 4032 Debrecen, Hungary
4
Department of Pharmacology, Faculty of Pharmacy, University of Debrecen, 4032 Debrecen, Hungary
*
Author to whom correspondence should be addressed.
Both authors contributed equally to this manuscript.
Academic Editors: Laura Coll-Planas, Sebastià Mas-Alos, Nicole Blackburn and Cristina Godinho
Int. J. Environ. Res. Public Health 2021, 18(12), 6594; https://doi.org/10.3390/ijerph18126594
Received: 19 May 2021 / Revised: 13 June 2021 / Accepted: 15 June 2021 / Published: 19 June 2021
Sarcopenia, defined as loss of muscle mass and strength, develops gradually with aging or after chronic disease. Efforts are ongoing to identify the best interventions that can slow down or stop sarcopenia. Nutrition-based interventions and exercise therapy may be beneficial; however, pharmacotherapy also could play a role. The effect of ACE inhibitors on physical performance is controversial. The present study investigates the impact of functional training on sarcopenia in the presence or absence of ACEi in elderly females. A total of 35 women over 65 years of age were selected for two groups on the basis that they were taking ACEi (n = 18) or not (n = 17). All subjects conducted a training program two times a week for 6 months. We examined various factors related to sarcopenia. After completing the short physical performance battery (SPPB) test, we found a significant improvement after 6 months of functional training. SPPB values of the ACEi group were significantly lower at the beginning of the study; however, we observed no difference between the SPPB results of the two groups after the training period. We conducted further studies to measure posture and spine mobility. Our Schober and Cobra test results revealed significantly improved spine mobility (both flexor and extensor) in both groups after 6 months of training. Furthermore, the grip strength of the hands, studied by an electric dynamometer, was significantly improved in both groups at the end of the training period. Our results indicated that functional training may improve body composition and muscle strength in patients diagnosed with sarcopenia. Furthermore, ACEi may be a helpful additional therapy in older adult patients suffering from severe sarcopenia. View Full-Text
Keywords: sarcopenia; elderly; ACE inhibitors; functional training sarcopenia; elderly; ACE inhibitors; functional training
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MDPI and ACS Style

Mile, M.; Balogh, L.; Papp, G.; Pucsok, J.M.; Szabó, K.; Barna, L.; Csiki, Z.; Lekli, I. Effects of Functional Training on Sarcopenia in Elderly Women in the Presence or Absence of ACE Inhibitors. Int. J. Environ. Res. Public Health 2021, 18, 6594. https://doi.org/10.3390/ijerph18126594

AMA Style

Mile M, Balogh L, Papp G, Pucsok JM, Szabó K, Barna L, Csiki Z, Lekli I. Effects of Functional Training on Sarcopenia in Elderly Women in the Presence or Absence of ACE Inhibitors. International Journal of Environmental Research and Public Health. 2021; 18(12):6594. https://doi.org/10.3390/ijerph18126594

Chicago/Turabian Style

Mile, Marianna, László Balogh, Gábor Papp, József M. Pucsok, Krisztina Szabó, Lilla Barna, Zoltán Csiki, and István Lekli. 2021. "Effects of Functional Training on Sarcopenia in Elderly Women in the Presence or Absence of ACE Inhibitors" International Journal of Environmental Research and Public Health 18, no. 12: 6594. https://doi.org/10.3390/ijerph18126594

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