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Review

The Rare, Unexpected Condition of a Twisted Leiomyoma in Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome: Etiopathogenesis, Diagnosis and Management. Our Experience and Narrative Review of the Literature

1
Institute for Maternal and Child Health, I.R.C.C.S. “Burlo Garofolo”, 34100 Trieste, Italy
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Department of Obstetrics and Gynecology, Azienda Sanitaria Universitaria Giuliano-Isontina, San Polo Hospital, Gorizia-Monfalcone, 34127 Trieste, Italy
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Clinical Department of Medical, Surgical and Health Sciences, University of Trieste, 34137 Trieste, Italy
4
UCO Pathological Anatomy and Histology, Azienda Ospedaliera-Universitaria Ospedali Riuniti, 34129 Trieste, Italy
*
Author to whom correspondence should be addressed.
Academic Editors: Milan Terzic, Antonio Simone Laganà and Antonio Sarria-Santamera
Int. J. Environ. Res. Public Health 2021, 18(11), 5895; https://doi.org/10.3390/ijerph18115895
Received: 9 April 2021 / Revised: 26 May 2021 / Accepted: 26 May 2021 / Published: 31 May 2021
(This article belongs to the Special Issue Women Health and Gynecology)
Uterine leiomyomas are a common finding in medical practice, but their frequency changes drastically when contextualized in a syndrome, as in the following case. A 50-year-old woman with a known Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome presented at our clinic with abdominal pain located in the lower quadrants and scarcely responsive to analgesic therapy. A twisted gynecological pelvic mass was diagnosed, and management for prompt resolution was adopted. Histologically the mass was described as a leiomyoma. The aim of the present study is to share our experience and to review the literature to compare different manifestation of the disease and different approach used in the various centers. The additional novelty of the paper is the immunohistochemical study we carried out on the leiomyoma that is contrasted with the current etiopathogenetic theories. View Full-Text
Keywords: Mayer-Rokitansky-Küster-Hauser; leiomyoma; pelvic mass; torsion Mayer-Rokitansky-Küster-Hauser; leiomyoma; pelvic mass; torsion
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MDPI and ACS Style

Romano, F.; Carlucci, S.; Stabile, G.; Mirenda, G.; Mirandola, M.; Mangino, F.P.; Romano, A.; Ricci, G. The Rare, Unexpected Condition of a Twisted Leiomyoma in Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome: Etiopathogenesis, Diagnosis and Management. Our Experience and Narrative Review of the Literature. Int. J. Environ. Res. Public Health 2021, 18, 5895. https://doi.org/10.3390/ijerph18115895

AMA Style

Romano F, Carlucci S, Stabile G, Mirenda G, Mirandola M, Mangino FP, Romano A, Ricci G. The Rare, Unexpected Condition of a Twisted Leiomyoma in Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome: Etiopathogenesis, Diagnosis and Management. Our Experience and Narrative Review of the Literature. International Journal of Environmental Research and Public Health. 2021; 18(11):5895. https://doi.org/10.3390/ijerph18115895

Chicago/Turabian Style

Romano, Federico, Stefania Carlucci, Guglielmo Stabile, Giuseppe Mirenda, Mariateresa Mirandola, Francesco P. Mangino, Andrea Romano, and Giuseppe Ricci. 2021. "The Rare, Unexpected Condition of a Twisted Leiomyoma in Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome: Etiopathogenesis, Diagnosis and Management. Our Experience and Narrative Review of the Literature" International Journal of Environmental Research and Public Health 18, no. 11: 5895. https://doi.org/10.3390/ijerph18115895

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