Atmospheric Pollution Exposure Increases Disease Activity of Systemic Lupus Erythematosus
Abstract
:1. Introduction
2. Material and Methods
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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SLEDAI | N | % | Mean | Median | SD | Variance | Min. | Max. |
---|---|---|---|---|---|---|---|---|
1st appointment | 69 | 71.9 | 6.63 | 5.00 | 4.61 | 21.27 | 0.00 | 16.00 |
2nd appointment | 15 | 15.6 | 6.16 | 5.50 | 5.07 | 25.75 | 0.00 | 17.00 |
3rd appointment | 12 | 12.5 | 5.97 | 4.00 | 4.80 | 23.03 | 0.00 | 16.00 |
Mean | Median | Standard Deviation | Variance | Minimum | Maximum | |
---|---|---|---|---|---|---|
CO (PPM) | ||||||
1st appointment | 0.06 | 0.01 | 0.07 | 0.01 | 0.01 | 0.25 |
2nd appointment | 0.08 | 0.10 | 0.06 | 0.00 | 0.01 | 0.24 |
3rd appointment | 0.13 | 0.13 | 0.07 | 0.00 | 0.01 | 0.25 |
PM2.5 (µm) | ||||||
1st appointment | 7.38 | 2.50 | 6.92 | 47.83 | 1.00 | 22.00 |
2nd appointment | 10.93 | 13.92 | 7.46 | 55.70 | 1.00 | 25.00 |
3rd appointment | 14.12 | 14.68 | 5.04 | 25.40 | 1.00 | 23.71 |
Temperature (°C) | ||||||
1st appointment | 28.38 | 28.50 | 1.56 | 2.44 | 23.90 | 30.80 |
2nd appointment | 27.83 | 28.50 | 1.89 | 3.58 | 23.00 | 30.80 |
3rd appointment | 28.45 | 27.80 | 2.47 | 6.12 | 23.60 | 32.70 |
Humidity (%) | ||||||
1st appointment | 55.58 | 59.00 | 15.26 | 232.86 | 24.00 | 81.46 |
2nd appointment | 56.98 | 56.35 | 11.19 | 125.28 | 27.71 | 71.00 |
3rd appointment | 54.93 | 55.00 | 13.85 | 191.71 | 26.50 | 82.92 |
Insolation (Gy) | ||||||
1st appointment | 5.87 | 5.70 | 1.61 | 2.58 | 1.90 | 8.60 |
2nd appointment | 8.75 | 6.80 | 13.75 | 189.806 | 3.70 | 82.5 |
3rd appointment | 6.32 | 6.90 | 1.96 | 3.84 | 2.50 | 9.60 |
Disease Manifestation | CO (PPM) | PM2.5 (µm) | ||||||
---|---|---|---|---|---|---|---|---|
Yes | No | Yes | No | |||||
Mean | SD | Mean | SD | Mean | SD | Mean | SD | |
Interstitial lung disease | 0.131 | 0.054 | 0.091 | 0.071 | 15.081 | 3.9411 | 11.177 | 6.805 * |
Myocarditis | 0.163 | 0.079 | 0.085 | 0.061 * | 17.716 | 5.114 | 10.654 | 6.280 * |
Myositis | 0.175 | 0.087 | 0.083 | 0.056 * | 18.498 | 7.455 | 10.514 | 5.685 * |
Osteonecrosis | 0.206 | 0.049 | 0.087 | 0.062 * | 19.603 | 2.629 | 10.978 | 6.378 * |
Pericarditis | 0.132 | 0.068 | 0.093 | 0.069 | 15.787 | 4.705 | 11.177 | 6.653 * |
Pleuritis | 0.130 | 0.070 | 0.089 | 0.070 | 15.621 | 4.302 | 11.088 | 6.714 * |
Dependent Variable: Variation in SLEDAI Score | ||||
---|---|---|---|---|
Parameters | β1 | Standard Deviation | Chi-square | Significance |
Fires | 1.464 | 0.636 | 5.296 | 0.021 |
CO | 8.451 | 3.410 | 6.141 | 0.013 |
PM2.5 | 0.012 | 0.034 | 0.119 | 0.730 |
Fires+CO | 10.800 | 3.198 | 11.401 | 0.001 |
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Blaskievicz, P.H.; Silva, A.M.C.; Fernandes, V.; Junior, O.B.P.; Shimoya-Bittencourt, W.; Ferreira, S.M.B.; da Silva, C.A.L. Atmospheric Pollution Exposure Increases Disease Activity of Systemic Lupus Erythematosus. Int. J. Environ. Res. Public Health 2020, 17, 1984. https://doi.org/10.3390/ijerph17061984
Blaskievicz PH, Silva AMC, Fernandes V, Junior OBP, Shimoya-Bittencourt W, Ferreira SMB, da Silva CAL. Atmospheric Pollution Exposure Increases Disease Activity of Systemic Lupus Erythematosus. International Journal of Environmental Research and Public Health. 2020; 17(6):1984. https://doi.org/10.3390/ijerph17061984
Chicago/Turabian StyleBlaskievicz, Paula Henriques, Ageo Mario Candido Silva, Vander Fernandes, Osvaldo Borges Pinto Junior, Walkiria Shimoya-Bittencourt, Silvana Margarida Benevides Ferreira, and Cristhiane Almeida Leite da Silva. 2020. "Atmospheric Pollution Exposure Increases Disease Activity of Systemic Lupus Erythematosus" International Journal of Environmental Research and Public Health 17, no. 6: 1984. https://doi.org/10.3390/ijerph17061984