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Current Status of Mumps Virus Infection: Epidemiology, Pathogenesis, and Vaccine

1
Department of Occupational Medicine, Chi-Mei Medical Center, Tainan 710, Taiwan
2
Department of Surveillance, Centers for Disease Control, Taipei 100, Taiwan
3
Department of Occupational Medicine, Tainan Municipal Hospital (managed by Show Chwan Medical Care Corporation), Tainan 701, Taiwan
4
Department of Public Health, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2020, 17(5), 1686; https://doi.org/10.3390/ijerph17051686
Received: 17 January 2020 / Revised: 28 February 2020 / Accepted: 29 February 2020 / Published: 5 March 2020
(This article belongs to the Section Infectious Disease Epidemiology)
Mumps is an important childhood infectious disease caused by mumps virus (MuV). We reviewed the epidemiology, pathogenesis, and vaccine development of mumps. Previous studies were identified using the key words “mumps” and “epidemiology”, “pathogenesis” or “vaccine” in MEDLINE, PubMed, Embase, Web of Science, and Google Scholar. We excluded the articles that were not published in the English language, manuscripts without abstracts, and opinion articles from the review. The number of cases caused by MuV decreased steeply after the introduction of the mumps vaccine worldwide. In recent years, a global resurgence of mumps cases in developed countries and cases of aseptic meningitis caused by some mumps vaccine strains have renewed the importance of MuV infection worldwide. The performance of mumps vaccination has become an important issue for controlling mumps infections. Vaccine development and routine vaccination are still effective measures to globally reduce the incidence of mumps infections. During outbreaks, a third of MMR vaccine is recommended for groups of persons determined by public authorities. View Full-Text
Keywords: mumps; epidemiology; pathogenesis; vaccine mumps; epidemiology; pathogenesis; vaccine
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MDPI and ACS Style

Su, S.-B.; Chang, H.-L.; Chen, K.-T. Current Status of Mumps Virus Infection: Epidemiology, Pathogenesis, and Vaccine. Int. J. Environ. Res. Public Health 2020, 17, 1686. https://doi.org/10.3390/ijerph17051686

AMA Style

Su S-B, Chang H-L, Chen K-T. Current Status of Mumps Virus Infection: Epidemiology, Pathogenesis, and Vaccine. International Journal of Environmental Research and Public Health. 2020; 17(5):1686. https://doi.org/10.3390/ijerph17051686

Chicago/Turabian Style

Su, Shih-Bin, Hsiao-Liang Chang, and Kow-Tong Chen. 2020. "Current Status of Mumps Virus Infection: Epidemiology, Pathogenesis, and Vaccine" International Journal of Environmental Research and Public Health 17, no. 5: 1686. https://doi.org/10.3390/ijerph17051686

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