Next Article in Journal
The Factorial Validity of the Norwegian Version of the Multicomponent Training Distress Scale (MTDS-N)
Next Article in Special Issue
Prevalence and Determinants of Bad Sleep Perception among Italian Children and Adolescents
Previous Article in Journal
Improving the Quality of Care in Care Homes Using the Quality Improvement Collaborative Approach: Lessons Learnt from Six Projects Conducted in the UK and The Netherlands
Previous Article in Special Issue
Patient Reported Outcome Measures of Sleep Quality in Fibromyalgia: A COSMIN Systematic Review
Article

The Role of Sleep Quality, Trait Anxiety and Hypothalamic-Pituitary-Adrenal Axis Measures in Cognitive Abilities of Healthy Individuals

1
Consorci Sanitari del Maresme, 08340 Mataró, Spain
2
Institut d’Investigació i Innovació Parc Taulí (I3PT), 08208 Sabadell, Spain
3
Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Carlos III Health Institute, 28029 Madrid, Spain
4
Department of Mental Health, Parc Taulí Hospital Universitari, Universitat Autònoma de Barcelona, 08208 Sabadell, Spain
5
Department of Psychiatry, Bellvitge University Hospital, 08907 L’Hospitalet de Llobregat, Spain
6
Neurosciences Group—Psychiatry and Mental Health, Biomedical Research Institute (IDIBELL), 08908 L’Hospitalet de Llobregat, Spain
7
Institut de Neurociències, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain
8
Hospital Universitari Institut Pere Mata, Institut d’Investigació Sanitària Pere Virgili (IISPV), Universitat Rovira i Virgili, 43206 Reus, Spain
9
Department of Clinical Sciences, School of Medicine, Universitat de Barcelona, 08907 L’Hospitalet de Llobregat, Spain
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2020, 17(20), 7600; https://doi.org/10.3390/ijerph17207600
Received: 23 August 2020 / Revised: 15 October 2020 / Accepted: 16 October 2020 / Published: 19 October 2020
(This article belongs to the Special Issue Sleep Quality Research)
Sleep plays a crucial role in cognitive processes. Sleep and wake memory consolidation seem to be regulated by glucocorticoids, pointing out the potential role of the hypothalamic-pituitary-adrenal (HPA) axis in the relationship between sleep quality and cognitive abilities. Trait anxiety is another factor that is likely to moderate the relationship between sleep and cognition, because poorer sleep quality and subtle HPA axis abnormalities have been reported in people with high trait anxiety. The current study aimed to explore whether HPA axis activity or trait anxiety moderate the relationship between sleep quality and cognitive abilities in healthy individuals. We studied 203 healthy individuals. We measured verbal and visual memory, working memory, processing speed, attention and executive function. Sleep quality was assessed with the Pittsburgh Sleep Quality Index. Trait anxiety was assessed with the State-Trait Anxiety Inventory. HPA axis measures included the cortisol awakening response (CAR), diurnal cortisol slope and cortisol levels during the day. Multiple linear regression analyses explored the relationship between sleep quality and cognition and tested potential moderating effects by HPA axis measures and trait anxiety. Poor sleep quality was associated with poorer performance in memory, processing speed and executive function tasks. In people with poorer sleep quality, a blunted CAR was associated with poorer verbal and visual memory and executive functions, and higher cortisol levels during the day were associated with poorer processing speed. Trait anxiety was a moderator of visual memory and executive functioning. These results suggest that subtle abnormalities in the HPA axis and higher trait anxiety contribute to the relationship between lower sleep quality and poorer cognitive functioning in healthy individuals. View Full-Text
Keywords: sleep quality; memory; cortisol; trait anxiety sleep quality; memory; cortisol; trait anxiety
MDPI and ACS Style

Labad, J.; Salvat-Pujol, N.; Armario, A.; Cabezas, Á.; de Arriba-Arnau, A.; Nadal, R.; Martorell, L.; Urretavizcaya, M.; Monreal, J.A.; Crespo, J.M.; Vilella, E.; Palao, D.J.; Menchón, J.M.; Soria, V. The Role of Sleep Quality, Trait Anxiety and Hypothalamic-Pituitary-Adrenal Axis Measures in Cognitive Abilities of Healthy Individuals. Int. J. Environ. Res. Public Health 2020, 17, 7600. https://doi.org/10.3390/ijerph17207600

AMA Style

Labad J, Salvat-Pujol N, Armario A, Cabezas Á, de Arriba-Arnau A, Nadal R, Martorell L, Urretavizcaya M, Monreal JA, Crespo JM, Vilella E, Palao DJ, Menchón JM, Soria V. The Role of Sleep Quality, Trait Anxiety and Hypothalamic-Pituitary-Adrenal Axis Measures in Cognitive Abilities of Healthy Individuals. International Journal of Environmental Research and Public Health. 2020; 17(20):7600. https://doi.org/10.3390/ijerph17207600

Chicago/Turabian Style

Labad, Javier, Neus Salvat-Pujol, Antonio Armario, Ángel Cabezas, Aida de Arriba-Arnau, Roser Nadal, Lourdes Martorell, Mikel Urretavizcaya, José A. Monreal, José M. Crespo, Elisabet Vilella, Diego J. Palao, José M. Menchón, and Virginia Soria. 2020. "The Role of Sleep Quality, Trait Anxiety and Hypothalamic-Pituitary-Adrenal Axis Measures in Cognitive Abilities of Healthy Individuals" International Journal of Environmental Research and Public Health 17, no. 20: 7600. https://doi.org/10.3390/ijerph17207600

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop