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A Scoping Review on Cue Reactivity in Methamphetamine Use Disorder

Research Division, Institute of Mental Health, Buangkok Green Medical Park, Singapore 539747, Singapore
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Author to whom correspondence should be addressed.
Both authors have contributed equally to this work.
Int. J. Environ. Res. Public Health 2020, 17(18), 6504; https://doi.org/10.3390/ijerph17186504
Received: 13 July 2020 / Revised: 29 August 2020 / Accepted: 31 August 2020 / Published: 7 September 2020
The experience of craving via exposure to drug-related cues often leads to relapse in drug users. This study consolidated existing empirical evidences of cue reactivity to methamphetamine to provide an overview of current literature and to inform the directions for future research. The best practice methodological framework for conducting scoping review by Arkey and O’Malley was adopted. Studies that have used a cue paradigm or reported on cue reactivity in persons with a history of methamphetamine use were included. Databases such as Medline, EMBASE, PsycINFO and CINAHL were searched using key terms, in addition to citation check and hand search. The search resulted in a total of 32 original research articles published between 2006 to 2020. Three main themes with regard to cue reactivity were identified and synthesized: (1) effects of cue exposure, (2) individual factors associated with cue reactivity, and (3) strategies that modulate craving or reactivity to cues. Exposure to methamphetamine-associated cues elicits significant craving and other autonomic reactivity. Evidence suggests that drug cue reactivity is strongly associated with indices of drug use and other individual-specific factors. Future studies should focus on high quality studies to support evidence-based interventions for reducing cue reactivity and to examine cue reactivity as an outcome measure. View Full-Text
Keywords: methamphetamine use disorder; cue reactivity; cue-induced craving; cue exposure methamphetamine use disorder; cue reactivity; cue-induced craving; cue exposure
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MDPI and ACS Style

Seow, L.S.E.; Ong, W.J.; Hombali, A.; AshaRani, P.V.; Subramaniam, M. A Scoping Review on Cue Reactivity in Methamphetamine Use Disorder. Int. J. Environ. Res. Public Health 2020, 17, 6504. https://doi.org/10.3390/ijerph17186504

AMA Style

Seow LSE, Ong WJ, Hombali A, AshaRani PV, Subramaniam M. A Scoping Review on Cue Reactivity in Methamphetamine Use Disorder. International Journal of Environmental Research and Public Health. 2020; 17(18):6504. https://doi.org/10.3390/ijerph17186504

Chicago/Turabian Style

Seow, Lee S.E., Wei J. Ong, Aditi Hombali, P. V. AshaRani, and Mythily Subramaniam. 2020. "A Scoping Review on Cue Reactivity in Methamphetamine Use Disorder" International Journal of Environmental Research and Public Health 17, no. 18: 6504. https://doi.org/10.3390/ijerph17186504

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