Next Article in Journal
Impact of the Sediment Organic vs. Mineral Content on Distribution of the Per- and Polyfluoroalkyl Substances (PFAS) in Lake Sediment
Next Article in Special Issue
Review of Drug Utilization Studies in Neonatal Units: A Global Perspective
Previous Article in Journal
Excess Deaths and Hospital Admissions for COVID-19 Due to a Late Implementation of the Lockdown in Italy
Previous Article in Special Issue
Paediatric Rational Prescribing: A Systematic Review of Assessment Tools
Open AccessArticle

Dispensing Practices of Fixed Dose Combination Controller Therapy for Asthma in Australian Children and Adolescents

1
Discipline of Paediatrics, School of Women’s and Children’s Health, Faculty of Medicine, The University of New South Wales, Sydney 2052, Australia
2
Respiratory Department, Sydney Children’s Hospital, Sydney 2031, Australia
3
Medicines Policy Research Unit, Centre for Big Data Research in Health, Sydney 2052, Australia
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2020, 17(16), 5645; https://doi.org/10.3390/ijerph17165645
Received: 3 June 2020 / Revised: 10 July 2020 / Accepted: 11 July 2020 / Published: 5 August 2020
(This article belongs to the Special Issue Drug Utilisation Studies in Paediatrics)
The Australian Asthma Handbook does not recommend use of fixed dose combination (FDC) controller medicines for asthma in children aged ≤5 years. FDCs are only recommended in children and adolescents (aged 6–18 years) not responding to initial inhaled corticosteroid (ICS) therapy. Using Pharmaceutical Benefits Scheme dispensing claims from 2013–2018, we examined the annual incident FDC dispensing and the incident FDC dispensing without prior ICS up to 365 days. We also determined cost of FDCs to government and patients. During 2013–2018, there were 35,635 FDC initiations and 31,368 (88%) did not have a preceding ICS dispensing. The annual incidence of FDC dispensing declined from 14.7 to 7.2/1000 children. Incidence of FDC dispensing/1000 children without a preceding ICS declined from 2.1 to 0.5 in children aged 1–2 years, 7.2 to 1.7 in 3–5 years, 14.8 to 5.1 in 6–11 years, and 18.6 to 11.9 in ≥12years. The cost of FDCs was 7.8 million Australian dollars (AUD); of which 4.4 million AUD was to government and 3.3 million AUD was to patient. Despite inappropriate dispensing of FDCs in children aged ≤5 years, incidence of FDC dispensing and more importantly incidence without a preceding ICS is declining in Australia. View Full-Text
Keywords: asthma controller; dispensing pattern; children asthma controller; dispensing pattern; children
Show Figures

Figure 1

MDPI and ACS Style

Homaira, N.; Daniels, B.; Pearson, S.; Jaffe, A. Dispensing Practices of Fixed Dose Combination Controller Therapy for Asthma in Australian Children and Adolescents. Int. J. Environ. Res. Public Health 2020, 17, 5645. https://doi.org/10.3390/ijerph17165645

AMA Style

Homaira N, Daniels B, Pearson S, Jaffe A. Dispensing Practices of Fixed Dose Combination Controller Therapy for Asthma in Australian Children and Adolescents. International Journal of Environmental Research and Public Health. 2020; 17(16):5645. https://doi.org/10.3390/ijerph17165645

Chicago/Turabian Style

Homaira, Nusrat; Daniels, Benjamin; Pearson, Sallie; Jaffe, Adam. 2020. "Dispensing Practices of Fixed Dose Combination Controller Therapy for Asthma in Australian Children and Adolescents" Int. J. Environ. Res. Public Health 17, no. 16: 5645. https://doi.org/10.3390/ijerph17165645

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop