Next Article in Journal
Incidence of Anorexia Nervosa in Women: A Systematic Review and Meta-Analysis
Previous Article in Journal
Association between Participation in Annual Physical Examinations and Risk Factors for Noncommunicable Diseases in Adults with Disabilities: Evidence from Shanghai, China
Article

Bayesian Regression Model for a Cost-Utility and Cost-Effectiveness Analysis Comparing Punch Grafting Versus Usual Care for the Treatment of Chronic Wounds

1
Department of Applied Economy, Facultad de Ciencias Económicas y Empresariales de Albacete, Universidad de Castilla La Mancha, Plaza de la Universidad 1, 02071 Albacete, Spain
2
Department of Dermatology, Hospital Universitario Infanta Leonor, Avenida Gran Vía del Este 80, 28031 Madrid, Spain
3
Department of Anesthesiology, Complejo Hospitalario Universitario de Albacete, Calle Hermanos Falcó 37, 02006 Albacete, Spain
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2020, 17(11), 3823; https://doi.org/10.3390/ijerph17113823
Received: 21 April 2020 / Revised: 25 May 2020 / Accepted: 26 May 2020 / Published: 28 May 2020
(This article belongs to the Section Health Care Sciences & Services)
Punch grafting is a traditional technique used to promote epithelialization of hard-to-heal wounds. The main purpose of this observational study was to conduct a cost-utility analysis (CUA) and a cost-effectiveness analysis (CEA) comparing punch grafting (n = 46) with usual care (n = 34) for the treatment of chronic wounds in an outpatient specialized wound clinic from a public healthcare system perspective (Spanish National Health system) with a three-month time horizon. CUA outcome was quality-adjusted life years (QALYs) calculated from EuroQoL-5D, whereas CEA outcome was wound-free period. One-way sensitivity analyses, extreme scenario analysis, and re-analysis by subgroups were conducted to fight against uncertainty. Bayesian regression models were built to explore whether differences between groups in costs, wound-free period, and QALYs could be explained by other variables different to treatment. As main results, punch grafting was associated with a reduction of 37% in costs compared to usual care, whereas mean incremental utility (0.02 ± 0.03 QALYs) and mean incremental effectiveness (7.18 ± 5.30 days free of wound) were favorable to punch grafting. All sensitivity analyses proved the robustness of our models. To conclude, punch grafting is the dominant alternative over usual care because it is cheaper and its utility and effectiveness are greater. View Full-Text
Keywords: health economics; economic evaluation; health outcomes; health care; quality-adjusted life years; EuroQoL-5D; sensitivity analysis health economics; economic evaluation; health outcomes; health care; quality-adjusted life years; EuroQoL-5D; sensitivity analysis
Show Figures

Graphical abstract

MDPI and ACS Style

Selva-Sevilla, C.; Conde-Montero, E.; Gerónimo-Pardo, M. Bayesian Regression Model for a Cost-Utility and Cost-Effectiveness Analysis Comparing Punch Grafting Versus Usual Care for the Treatment of Chronic Wounds. Int. J. Environ. Res. Public Health 2020, 17, 3823. https://doi.org/10.3390/ijerph17113823

AMA Style

Selva-Sevilla C, Conde-Montero E, Gerónimo-Pardo M. Bayesian Regression Model for a Cost-Utility and Cost-Effectiveness Analysis Comparing Punch Grafting Versus Usual Care for the Treatment of Chronic Wounds. International Journal of Environmental Research and Public Health. 2020; 17(11):3823. https://doi.org/10.3390/ijerph17113823

Chicago/Turabian Style

Selva-Sevilla, Carmen, Elena Conde-Montero, and Manuel Gerónimo-Pardo. 2020. "Bayesian Regression Model for a Cost-Utility and Cost-Effectiveness Analysis Comparing Punch Grafting Versus Usual Care for the Treatment of Chronic Wounds" International Journal of Environmental Research and Public Health 17, no. 11: 3823. https://doi.org/10.3390/ijerph17113823

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop