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Int. J. Environ. Res. Public Health 2019, 16(2), 260; https://doi.org/10.3390/ijerph16020260

Potential Effects of Lung Function Reduction on Health-Related Quality of Life

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1
Department of Occupational & Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
2
Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
*
Author to whom correspondence should be addressed.
Received: 30 November 2018 / Revised: 2 January 2019 / Accepted: 4 January 2019 / Published: 17 January 2019
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Abstract

Health-related quality of life (HRQOL) was reported to reflect overall quality of life and individual perceptions related to health. Decreased lung function is associated with reduced ventilation and oxygen intake and reported to affect body functions. However, the effect of lung function reduction on HRQOL is still unclear. A total of 8398 retired workers from Dongfeng-Tongji Cohort Study were included in this cross section study. Lung function was measured using an electronic spirometer. HRQOL was evaluated through a questionnaire designed according to the WHOQOL-BREF. The mean of the HRQOL scores of its four domains (physical health, psychological state, social relationships and environment) is the total HRQOL score. A general linear model was used to analyse the association between lung function and HRQOL. In the continuous analysis by the general linear model, FVC was associated with the total HRQOL, physical health domain and social relationships domain scores. In the categorical analysis, there was a linear trend between FVC and the total HRQOL and physical health scores. We also found a similar relationship between FEV1 and HRQOL scores. Further analysis suggested that elevated lung function could improve the scores of pain and discomfort facet and independence facet of physical health domain. The lung function was significantly positively associated with HRQOL in middle-aged and older Chinese. View Full-Text
Keywords: forced vital capacity; forced expiratory volume; lung disease; health-related quality of life forced vital capacity; forced expiratory volume; lung disease; health-related quality of life
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Wen, Y.; Wang, D.; Zhou, M.; Zhou, Y.; Guo, Y.; Chen, W. Potential Effects of Lung Function Reduction on Health-Related Quality of Life. Int. J. Environ. Res. Public Health 2019, 16, 260.

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