Toxoplasma gondii Serointensity and Seropositivity: Heritability and Household-Related Associations in the Old Order Amish
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Population
2.2. Plasma Collection
2.3. Laboratory Analysis
2.4. Statistical Analysis
3. Results
3.1. T. gondii IgG Antibody Titers
3.2. Heritability
3.3. Household
4. Discussion
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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All (N = 2017) | Men (N = 850, 42%) | Women (N = 1167, 58%) | |
---|---|---|---|
Age, mean (SD) | 44.0 (17.0) | 45.5 (16.5) | 42.9 (17.2) |
BMI, mean (SD) | 26.6 (5.0) | 26.0 (4.1) | 27.1 (5.5) |
T. gondii antibody titer, IU/mL, mean (SD) | 48.5 (66.0) | 52.2 (63.0) | 45.8 (68.0) |
Log (titer), mean (SD) | 2.7 (1.9) | 2.9 (1.8) | 2.5 (1.9) |
Seropositive, N/total (%) | 1098/2017(54.4) | 518/850(60.9) | 580/1167(49.7) |
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Duffy, A.R.; O’Connell, J.R.; Pavlovich, M.; Ryan, K.A.; Lowry, C.A.; Daue, M.; Raheja, U.K.; Brenner, L.A.; Markon, A.O.; Punzalan, C.M.; et al. Toxoplasma gondii Serointensity and Seropositivity: Heritability and Household-Related Associations in the Old Order Amish. Int. J. Environ. Res. Public Health 2019, 16, 3732. https://doi.org/10.3390/ijerph16193732
Duffy AR, O’Connell JR, Pavlovich M, Ryan KA, Lowry CA, Daue M, Raheja UK, Brenner LA, Markon AO, Punzalan CM, et al. Toxoplasma gondii Serointensity and Seropositivity: Heritability and Household-Related Associations in the Old Order Amish. International Journal of Environmental Research and Public Health. 2019; 16(19):3732. https://doi.org/10.3390/ijerph16193732
Chicago/Turabian StyleDuffy, Allyson R., Jeffrey R. O’Connell, Mary Pavlovich, Kathleen A. Ryan, Christopher A. Lowry, Melanie Daue, Uttam K. Raheja, Lisa A. Brenner, André O. Markon, Cecile M. Punzalan, and et al. 2019. "Toxoplasma gondii Serointensity and Seropositivity: Heritability and Household-Related Associations in the Old Order Amish" International Journal of Environmental Research and Public Health 16, no. 19: 3732. https://doi.org/10.3390/ijerph16193732