Oral Health Status and Behavior among Cancer Survivors in Korea Using Nationwide Survey
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Acknowledgments
Conflicts of Interest
References
- Torre, L.A.; Bray, F.; Siegel, R.L.; Ferlay, J.; Lortet-Tieulent, J.; Jemal, A. Global cancer statistics, 2012. CA Cancer J. Clin. 2015, 65, 87–108. [Google Scholar] [CrossRef] [PubMed]
- Jung, K.W.; Won, Y.J.; Kong, H.J.; Oh, C.M.; Cho, H.; Lee, D.H.; Lee, K.H. Cancer statistics in Korea: Incidence, mortality, survival, and prevalence in 2012. Cancer Res. Treat. 2015, 47, 127–141. [Google Scholar] [CrossRef] [PubMed]
- Taichman, L.S.; Gomez, G.; Inglehart, M.R. Oral health-related complications of breast cancer treatment: Assessing dental hygienists’ knowledge and professional practice. J. Dent. Hyg. 2014, 88, 100–113. [Google Scholar] [PubMed]
- Amodio, J.; Palioto, D.B.; Carrara, H.H.; Tiezzi, D.G.; Andrade, J.M.; Reis, F.J. Oral health after breast cancer treatment in postmenopausal women. Clinics 2014, 69, 706–708. [Google Scholar] [CrossRef] [PubMed]
- Keefe, D.M.; Schubert, M.M.; Elting, L.S.; Sonis, S.T.; Epstein, J.B.; Raber-Durlacher, J.E.; Migliorati, C.A.; McGuire, D.B.; Hutchins, R.D.; Peterson, D.E. Updated clinical practice guidelines for the prevention and treatment of mucositis. Cancer 2007, 109, 820–831. [Google Scholar] [CrossRef] [PubMed]
- Sonis, S.T.; Elting, L.S.; Keefe, D.; Peterson, D.E.; Schubert, M.; Hauer-Jensen, M.; Bekele, B.N.; Raber-Durlacher, J.; Donnelly, J.P.; Rubenstein, E.B. Perspectives on cancer therapy-induced mucosal injury: Pathogenesis, measurement, epidemiology, and consequences for patients. Cancer 2004, 100, 1995–2025. [Google Scholar] [CrossRef] [PubMed]
- PDQ Supportive and Palliative Care Editorial Board. Oral Complications of Chemotherapy and Head/Neck Radiation (PDQ(R)): Health Professional Version. In PDQ Cancer Information Summaries; National Cancer Institute (US): Bethesda, MD, USA, 2002. [Google Scholar]
- Jellema, A.P.; Slotman, B.J.; Doornaert, P.; Leemans, C.R.; Langendijk, J.A. Impact of radiation-induced xerostomia on quality of life after primary radiotherapy among patients with head and neck cancer. Int. J. Radiat. Oncol. Biol. Phys. 2007, 69, 751–760. [Google Scholar] [CrossRef] [PubMed]
- Shiboski, C.H.; Hodgson, T.A.; Ship, J.A.; Schiodt, M. Management of salivary hypofunction during and after radiotherapy. Oral Surg Oral Med. Oral Pathol. Oral Radiol. Endod. 2007, 103, e1–e19. [Google Scholar] [CrossRef] [PubMed]
- Jensen, S.B.; Pedersen, A.M.; Vissink, A.; Andersen, E.; Brown, C.G.; Davies, A.N.; Dutilh, J.; Fulton, J.S.; Jankovic, L.; Lopes, N.N.; et al. A systematic review of salivary gland hypofunction and xerostomia induced by cancer therapies: Prevalence, severity and impact on quality of life. Support. Care Cancer 2010, 18, 1039–1060. [Google Scholar] [CrossRef] [PubMed]
- Liu, J.C.; Shah, J.P. Surgical technique refinements in head and neck oncologic surgery. J. Surg. Oncol. 2010, 101, 661–668. [Google Scholar] [CrossRef] [PubMed]
- Humphris, G.M.; Ozakinci, G. Psychological responses and support needs of patients following head and neck cancer. Int. J. Surg. 2006, 4, 37–44. [Google Scholar] [CrossRef] [PubMed]
- Arigbede, A.O.; Babatope, B.O.; Bamidele, M.K. Periodontitis and systemic diseases: A literature review. J. Indian Soc. Periodontol. 2012, 16, 487–491. [Google Scholar] [CrossRef] [PubMed]
- Wong, H.M. Oral complications and management strategies for patients undergoing cancer therapy. Sci. World J. 2014, 2014, 581795. [Google Scholar] [CrossRef] [PubMed]
- Kim, H.J.; Kim, Y.H.; Cho, K.H.; Han, B.D.; Kim, S.M.; Choi, Y.S.; Kim, D.H.; Do Han, K.; Lee, Y.J.; Kim, C.M. Oral health behaviors and bone mineral density in South Korea: The 2008–2010 Korean National Health and Nutrition Examination Survey. J. Bone Miner. Metab. 2016, 34, 225–233. [Google Scholar] [CrossRef] [PubMed]
- Park, S.J.; Ko, K.D.; Shin, S.I.; Ha, Y.J.; Kim, G.Y.; Kim, H.A. Association of oral health behaviors and status with depression: Results from the Korean National Health and Nutrition Examination Survey, 2010. J. Public Health Dent. 2014, 74, 127–138. [Google Scholar] [CrossRef] [PubMed]
- Han, K.; Park, J.B. Association between oral health behavior and periodontal disease among Korean adults: The Korea national health and nutrition examination survey. Medicine 2017, 96, e6176. [Google Scholar] [CrossRef] [PubMed]
- Kumar, S.; Tadakamadla, J.; Johnson, N.W. Effect of Toothbrushing Frequency on Incidence and Increment of Dental Caries: A Systematic Review and Meta-Analysis. J. Dent. Res. 2016, 95, 1230–1236. [Google Scholar] [CrossRef] [PubMed]
- Sato, F.; Oze, I.; Kawakita, D.; Yamamoto, N.; Ito, H.; Hosono, S.; Suzuki, T.; Kawase, T.; Furue, H.; Watanabe, M.; et al. Inverse association between toothbrushing and upper aerodigestive tract cancer risk in a Japanese population. Head Neck 2011, 33, 1628–1637. [Google Scholar] [CrossRef] [PubMed]
- Chen, H.; Nie, S.; Zhu, Y.; Lu, M. Teeth loss, teeth brushing and esophageal carcinoma: A systematic review and meta-analysis. Sci. Rep. 2015, 5, 15203. [Google Scholar] [CrossRef] [PubMed]
- Poklepovic, T.; Worthington, H.V.; Johnson, T.M.; Sambunjak, D.; Imai, P.; Clarkson, J.E.; Tugwell, P. Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults. Cochrane Database Syst. Rev. 2013, Cd009857. [Google Scholar] [CrossRef] [PubMed]
- Yoshioka, M.; Shirayama, Y.; Imoto, I.; Hinode, D.; Yanagisawa, S.; Takeuchi, Y.; Bando, T.; Yokota, N. Factors associated with regular dental visits among hemodialysis patients. World J. Nephrol. 2016, 5, 455–460. [Google Scholar] [CrossRef] [PubMed]
- Aggarwal, A.; Panat, S.R. Oral health behavior and HbA1c in Indian adults with type 2 diabetes. J. Oral Sci. 2012, 54, 293–301. [Google Scholar] [CrossRef] [PubMed]
- Epstein, J.B.; Stevenson-Moore, P. Periodontal disease and periodontal management in patients with cancer. Oral Oncol. 2001, 37, 613–619. [Google Scholar] [CrossRef]
- Zee, K.Y. Smoking and periodontal disease. Aust. Dent. J. 2009, 54, S44–S50. [Google Scholar] [CrossRef] [PubMed]
- Kinane, D.F.; Chestnutt, I.G. Smoking and periodontal disease. Crit. Rev. Oral Biol. Med. 2000, 11, 356–365. [Google Scholar] [CrossRef] [PubMed]
- Hou, L.; Hong, X.; Dai, M.; Chen, P.; Zhao, H.; Wei, Q.; Li, F.; Tan, W. Association of smoking status with prognosis in bladder cancer: A meta-analysis. Oncotarget 2017, 8, 1278–1289. [Google Scholar] [CrossRef] [PubMed]
- Parsons, A.; Daley, A.; Begh, R.; Aveyard, P. Influence of smoking cessation after diagnosis of early stage lung cancer on prognosis: Systematic review of observational studies with meta-analysis. BMJ 2010, 340, b5569. [Google Scholar] [CrossRef] [PubMed]
- Van Dyke, T.E.; Sheilesh, D. Risk factors for periodontitis. J. Int. Acad. Periodontol. 2005, 7, 3–7. [Google Scholar] [PubMed]
- McLaughlin, V.H.; Trentham-Dietz, A.; Hampton, J.M.; Newcomb, P.A.; Sprague, B.L. Lifestyle factors and the risk of a second breast cancer after ductal carcinoma in situ. Cancer Epidemiol. Biomark. Prev. 2014, 23, 450–460. [Google Scholar] [CrossRef] [PubMed]
- Kwan, M.L.; Kushi, L.H.; Weltzien, E.; Tam, E.K.; Castillo, A.; Sweeney, C.; Caan, B.J. Alcohol consumption and breast cancer recurrence and survival among women with early-stage breast cancer: The life after cancer epidemiology study. J. Clin. Oncol. 2010, 28, 4410–4416. [Google Scholar] [CrossRef] [PubMed]
- Schultz, P.N.; Beck, M.L.; Stava, C.; Vassilopoulou-Sellin, R. Health profiles in 5836 long-term cancer survivors. Int. J. Cancer. 2003, 104, 488–495. [Google Scholar] [CrossRef] [PubMed]
- Perry, A.D.; Iida, H.; Patton, L.L.; Wilder, R.S. Knowledge, Perceived Ability and Practice Behaviors Regarding Oral Health among Pediatric Hematology and Oncology Nurses. J. Dent. Hyg. 2015, 89, 219–228. [Google Scholar] [PubMed]
Characteristics | Self-Reported History of Cancer (n = 640) | No Reported Cancer History (n = 2560) | p-Value |
---|---|---|---|
Sex | 1.000 | ||
Men | 245(38.3) | 980(38.3) | |
Women | 395(61.7) | 1580(61.7) | |
Age (years) | 1.000 | ||
19–44 | 61(9.5) | 244(9.5) | |
45–64 | 260(40.6) | 1040(40.6) | |
≥65 | 319(49.8) | 1276(49.8) | |
Household income | 0.834 | ||
Low | 191(30) | 761(29.9) | |
Middle-low | 175(27.5) | 658(25.8) | |
Middle-high | 137(21.5) | 569(22.4) | |
High | 134(21) | 558(21.9) | |
Education | 0.862 | ||
≤Elementary school | 253(39.8) | 1005(40.7) | |
Middle school | 99(15.6) | 366(14.8) | |
≥High school | 284(44.7) | 1098(44.5) | |
Smoking status | <0.001 | ||
Never | 402(62.8) | 1628(63.6) | |
Former | 184(28.8) | 597(23.3) | |
Current | 54(8.4) | 334(13.1) | |
Drinking frequency | 0.008 | ||
None | 295(46.1) | 1012(39.5) | |
≤once/month | 148(23.1) | 698(27.3) | |
≥twice/month | 197(30.8) | 850(33.2) | |
Non-cancer, chronic diseases | 0.002 | ||
No | 207(32.3) | 992(38.8) | |
Yes | 433(67.7) | 1568(61.3) | |
Age at diagnosis (years) | |||
19–44 | 161(25.2) | ||
45–64 | 337(52.7) | ||
≥65 | 141(22.1) | ||
Time since diagnosis (years) | |||
<1 | 81(12.7) | ||
<5 | 219(34.3) | ||
≥5 | 339(53.1) | ||
Cancer site | |||
Stomach | 134(21) | ||
Liver | 16(2.5) | ||
Colorectum | 73(11.4) | ||
Breast | 84(13.2) | ||
Cervix | 78(12.2) | ||
Lung | 17(2.7) | ||
Thyroid | 121(18.9) | ||
Other | 116(18.2) | ||
Currently suffering from cancer | |||
No | 363(56.7) | ||
Yes | 277(43.3) |
Characteristics | Self-Reported History of Cancer | No Reported Cancer History | p-Value |
---|---|---|---|
Oral health status | |||
Subjective oral health | 0.831 | ||
Poor | 14.8 | 15.4 | |
Fair | 37.0 | 37.9 | |
Good | 48.1 | 46.8 | |
aOR (95% CI) for poor oral health a | 1.03(0.86–1.23) | 1.00 | |
Chewing difficulties due to oral health problems | 0.781 | ||
No | 65.2 | 64.6 | |
Yes | 34.8 | 35.4 | |
aOR (95% CI) for chewing difficulties a | 0.97(0.79–1.17) | 1.00 | |
Speech difficulties due to oral health problems | 0.660 | ||
No | 84.7 | 84.0 | |
Yes | 15.3 | 16.0 | |
aOR (95% CI) for speech difficulties a | 0.92(0.71–1.18) | 1.00 | |
Periodontal disease | 0.032 | ||
No | 63.4 | 58.7 | |
Yes | 36.6 | 41.3 | |
aOR (95% CI) for periodontal disease a | 0.82(0.67–0.99) | 1.00 | |
Denture needs | 0.588 | ||
No | 84.1 | 84.9 | |
Yes | 15.9 | 15.1 | |
aOR (95% CI) for denture needs a | 1.06(0.83–1.36) | 1.00 | |
Oral health behavior | |||
Daily teeth brushing frequency | 0.610 | ||
Once a day or less | 16.3 | 15.8 | |
Twice a day | 42.5 | 40.8 | |
Three or more times a day | 41.3 | 43.4 | |
aOR (95% CI) for teeth brushing ≥3 times a | 0.88(0.73–1.06) | 1.00 | |
Floss use | 0.119 | ||
No | 83.0 | 85.4 | |
Yes | 17.0 | 14.6 | |
Mouthwash use | 0.704 | ||
No | 80.0 | 80.7 | |
Yes | 20.0 | 19.3 | |
Interdental brush | 0.792 | ||
No | 84.1 | 83.6 | |
Yes | 15.9 | 16.4 | |
Electric toothbrush | 0.012 | ||
No | 94.5 | 96.6 | |
Yes | 5.5 | 3.4 | |
Use of secondary oral products | 0.124 | ||
0 | 55.2 | 59.3 | |
1 | 34.1 | 30.0 | |
2 or more | 10.8 | 10.7 | |
aOR (95% CI) for use a | 1.16(0.96–1.42) | 1.00 | |
Oral health screening use | 0.037 | ||
No | 69.2 | 73.3 | |
Yes | 30.8 | 26.7 | |
aOR (95% CI) for oral health screening a | 1.23(1.01–1.50) | 1.00 |
Characteristics | Poor Self-Rated Oral Health | Chewing Difficulties Due to Oral Health Problems | Speaking Difficulties Due to Oral Health Problems | Periodontal Disease | Denture Needs |
---|---|---|---|---|---|
Sex (/women) | |||||
Men | 1.22(0.64–2.35) | 0.94(0.47–1.91) | 1.11(0.44–2.83) | 1.82(0.95–3.48) | 1.01(0.43–2.36) |
Age (/19–44 years) | |||||
45–64 | 0.80(0.42–1.53) | 1.97(0.79–4.91) | 3.04(0.38–24.31) | 1.24(0.59–2.58) | 3.16(0.69–14.41) |
≥65 | 0.68(0.32–1.42) | 2.91(1.10–7.70) | 5.57(0.68–45.82) | 1.53(0.69–3.39) | 5.56(1.17–26.38) |
Household income(/high) | |||||
Low | 2.50(1.44–4.33) | 1.66(0.91–3.03) | 1.03(0.48–2.23) | 1.56(0.90–2.69) | 0.97(0.47–2.02) |
Middle-low | 1.40(0.83–2.34) | 0.92(0.51–1.68) | 0.74(0.34–1.64) | 1.22(0.71–2.07) | 1.05(0.51–2.16) |
Middle-high | 1.43(0.84–2.44) | 1.40(0.76–2.58) | 0.94(0.40–2.23) | 1.21(0.70–2.12) | 1.21(0.56–2.62) |
Education(/≥high school) | |||||
≤elementary school | 1.41(0.88–2.26) | 2.01(1.22–3.31) | 2.87(1.44–5.71) | 1.76(1.11–2.81) | 2.26(1.23–4.17) |
Middle school | 0.73(0.42–1.27) | 1.56(0.88–2.77) | 2.30(1.02–5.18) | 1.78(1.05–3.02) | 2.31(1.15–4.62) |
Smoking status (/never) | |||||
Former | 1.54(0.85–2.78) | 1.42(0.75–2.69) | 1.63(0.71–3.75) | 1.28(0.71–2.30) | 1.35(0.62–2.96) |
Current | 1.90(0.87–4.16) | 1.75(0.78–3.94) | 1.53(0.50–4.66) | 2.14(1.01–4.52) | 1.31(0.51–3.38) |
Drinking frequency (/none) | |||||
≤once/month | 1.37(0.86–2.18) | 0.62(0.37–1.05) | 0.58(0.29–1.18) | 0.77(0.48–1.24) | 0.68(0.36–1.31) |
≥twice/month | 0.88(0.56–1.39) | 0.90(0.55–1.45) | 0.61(0.32–1.17) | 0.76(0.49–1.20) | 1.03(0.59–1.81) |
Chronic disease (/no) | |||||
Yes | 0.76(0.50–1.14) | 1.18(0.75–1.85) | 1.23(0.65–2.32) | 0.85(0.57–1.28) | 0.89(0.52–1.54) |
Time since diagnosis (/<1 years) | |||||
<5 | 1.40(0.78–2.50) | 0.68(0.36–1.28) | 1.09(0.45–2.68) | 0.87(0.48–1.56) | 0.62(0.31–1.27) |
≥5 | 1.83(0.97–3.47) | 1.26(0.64–2.48) | 2.07(0.82–5.22) | 0.97(0.51–1.82) | 0.64(0.30–1.38) |
Cancer site (/stomach) | |||||
Liver | 1.52(0.48–4.79) | 1.12(0.33–3.87) | 1.70(0.38–7.53) | 1.19(0.39–3.61) | 2.15(0.50–9.22) |
Colorectum | 1.28(0.67–2.46) | 1.16(0.59–2.28) | 0.63(0.23–1.71) | 0.95(0.51–1.77) | 2.81(1.28–6.15) |
Breast | 0.98(0.49–1.95) | 0.82(0.37–1.81) | 1.80(0.68–4.78) | 1.56(0.79–3.06) | 1.24(0.44–3.52) |
Cervix | 1.21(0.60–2.43) | 1.82(0.87–3.82) | 1.21(0.45–3.21) | 0.62(0.30–1.29) | 2.13(0.86–5.32) |
Lung | 0.43(0.12–1.49) | 1.47(0.44–4.86) | 1.09(0.25–4.82) | 0.54(0.16–1.79) | 1.30(0.32–5.29) |
Thyroid | 1.65(0.86–3.14) | 2.20(1.09–4.45) | 1.51(0.59–3.85) | 1.05(0.55–2.00) | 2.73(1.17–6.41) |
Other | 0.97(0.55–1.71) | 1.33(0.72–2.44) | 1.72(0.79–3.73) | 0.87(0.50–1.52) | 2.01(0.95–4.25) |
Current suffering from cancer (/no) | |||||
Yes | 2.11(1.34–3.34) | 1.39(0.85–2.27) | 1.67(0.89–3.14) | 0.80(0.51–1.26) | 0.79(0.45–1.41) |
Periodontal disease (/no) | |||||
Yes | 1.93(1.34–2.80) | 1.51(1.02–2.23) | 0.78(0.46–1.31) | - | - |
Denture needs (/no) | |||||
Yes | 2.86(1.73–4.74) | 2.62(1.62–4.23) | 1.91(1.07–3.42) | - | - |
Characteristics | Toothbrushing ≥3 Times a Day | Use of Secondary Oral Products | Oral Health Screening Use |
---|---|---|---|
Sex (/women) | |||
Men | 1.01(0.53–1.94) | 0.51(0.26–1.02) | 1.95(0.96–3.97) |
Age (/≥65 years) | |||
19–44 | 2.29(1.11–4.72) | 1.18(0.55–2.51) | 1.41(0.68–2.91) |
45–64 | 1.55(1.01–2.38) | 1.48(0.96–2.29) | 1.19(0.76–1.87) |
Household income(/low) | |||
Middle-low | 0.88(0.54–1.42) | 1.35(0.82–2.22) | 1.35(0.79–2.30) |
Middle-high | 0.69(0.40–1.17) | 1.66(0.95–2.88) | 1.47(0.82–2.61) |
High | 0.68(0.39–1.18) | 2.05(1.16–3.61) | 1.50(0.84–2.68) |
Education (/≤elementary school) | |||
Middle school | 1.05(0.61–1.84) | 1.14(0.65–2.01) | 1.82(1.01–3.28) |
≥High school | 2.70(1.67–4.37) | 4.60(2.79–7.59) | 3.15(1.89–5.23) |
Smoking status (/current) | |||
Never | 1.65(0.76–3.59) | 0.47(0.21–1.04) | 1.77(0.75–4.17) |
Former | 0.83(0.41–1.70) | 0.54(0.26–1.09) | 1.53(0.72–3.27) |
Drinking frequency (/≥twice/month) | |||
None | 0.99(0.63–1.55) | 1.44(0.90–2.31) | 1.22(0.76–1.97) |
≤once/month | 1.17(0.72–1.91) | 1.83(1.09–3.07) | 0.89(0.53–1.50) |
Chronic disease (/yes) | |||
No | 0.75(0.50–1.13) | 0.69(0.45–1.06) | 0.79(0.52–1.20) |
Time since diagnosis (/≥5 years) | |||
<1 | 1.41(0.74–2.69) | 1.32(0.68–2.55) | 0.71(0.35–1.41) |
<5 | 1.12(0.71–1.77) | 0.97(0.60–1.56) | 1.33(0.83–2.12) |
Cancer site (/stomach) | |||
Liver | 1.72(0.55–5.37) | 0.53(0.16–1.81) | 1.23(0.39–3.89) |
Colorectum | 1.06(0.56–2.03) | 1.39(0.70–2.77) | 1.00(0.50–2.03) |
Breast | 0.79(0.40–1.56) | 1.63(0.79–3.33) | 1.15(0.54–2.42) |
Cervix | 0.78(0.39–1.56) | 1.84(0.88–3.82) | 1.05(0.47–2.35) |
Lung | 0.41(0.08–2.01) | 1.45(0.39–5.37) | 1.56(0.43–5.69) |
Thyroid | 1.17(0.62–2.22) | 1.64(0.84–3.20) | 1.72(0.87–3.41) |
Other | 1.01(0.57–1.78) | 1.02(0.56–1.86) | 0.96(0.52–1.76) |
Current suffering from cancer(/yes) | |||
No | 1.44(0.91–2.27) | 0.81(0.51–1.30) | 1.07(0.67–1.71) |
Periodontal disease (/no) | |||
Yes | 0.77(0.53–1.11) | 1.07(0.72–1.59) | 0.91(0.61–1.36) |
Denture needs (/no) | |||
Yes | 1.43(0.89–2.32) | 0.98(0.59–1.61) | 1.01(0.59–1.74) |
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Han, M.A. Oral Health Status and Behavior among Cancer Survivors in Korea Using Nationwide Survey. Int. J. Environ. Res. Public Health 2018, 15, 14. https://doi.org/10.3390/ijerph15010014
Han MA. Oral Health Status and Behavior among Cancer Survivors in Korea Using Nationwide Survey. International Journal of Environmental Research and Public Health. 2018; 15(1):14. https://doi.org/10.3390/ijerph15010014
Chicago/Turabian StyleHan, Mi Ah. 2018. "Oral Health Status and Behavior among Cancer Survivors in Korea Using Nationwide Survey" International Journal of Environmental Research and Public Health 15, no. 1: 14. https://doi.org/10.3390/ijerph15010014
APA StyleHan, M. A. (2018). Oral Health Status and Behavior among Cancer Survivors in Korea Using Nationwide Survey. International Journal of Environmental Research and Public Health, 15(1), 14. https://doi.org/10.3390/ijerph15010014