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Open AccessArticle

Seroprevalence of Measles Antibodies and Predictors for Seropositivity among Chinese Children

Department of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an 710061, China
Department of Medicine, University of Tennessee Medical Center, Knoxville, TN 37920, USA
Center for Disease Control and Prevention in Qian County, Xianyang 713300, China
Author to whom correspondence should be addressed.
Academic Editor: Paul B. Tchounwou
Int. J. Environ. Res. Public Health 2017, 14(6), 605;
Received: 13 March 2017 / Revised: 22 May 2017 / Accepted: 2 June 2017 / Published: 6 June 2017
(This article belongs to the Section Global Health)
Background: Supplementary measles immunization has been implemented since 2010 throughout China, yet few studies have reported its effect in the northwest regions. Methods: A cross-sectional study was conducted among children aged 2 to 4 years old (n = 755) from February to September 2014 in 25 towns of Qian County, Shaanxi Province. Blood samples were analyzed for measles antibodies using enzyme-linked immunosorbent immunoglobulin G (IgG) assays. Socio-demographic factors were assessed by questionnaire. Data on vaccine dose were collected from town medical records. Univariate and logistic regression analyses were used to determine factors associated with measles antibody seropositivity. Results: Measles antibody seroprevalence was 91.13% (95% CI: 89.52–92.83) in our sample. Compared with children whose mother’s highest education was primary school, seroprevalence was higher in children whose maternal education was middle school (adjusted OR: 1.4, 95% CI: 0.7–2.8), high school (adjusted OR: 2.4, 95% CI: 1.3–7.7), and college/university (adjusted OR: 2.9, 95% CI: 1.2–9.3). Vaccine dose was positively associated with seropositivity. Conclusions: Measles seroprevalence is high in China and is associated with the mother’s education and vaccine dose. View Full-Text
Keywords: seroprevalence; measles; vaccine dose; predictor seroprevalence; measles; vaccine dose; predictor
MDPI and ACS Style

Wang, X.; Ma, M.; Hui, Z.; Terry, P.D.; Zhang, Y.; Su, R.; Wang, M.; Gu, W.; Li, L. Seroprevalence of Measles Antibodies and Predictors for Seropositivity among Chinese Children. Int. J. Environ. Res. Public Health 2017, 14, 605.

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