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Open AccessReview

New Immunotherapy Strategies in Breast Cancer

by Lin-Yu Yu 1,2, Jie Tang 1,2, Cong-Min Zhang 1,2, Wen-Jing Zeng 1,2, Han Yan 1,2, Mu-Peng Li 1,2 and Xiao-Ping Chen 1,2,*
1
Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, China
2
Institute of Clinical Pharmacology, Central South University, Hunan Key Laboratory of Pharmacogenetics, Changsha 410078, China
*
Author to whom correspondence should be addressed.
Academic Editor: William Chi-shing Cho
Int. J. Environ. Res. Public Health 2017, 14(1), 68; https://doi.org/10.3390/ijerph14010068
Received: 9 October 2016 / Revised: 5 January 2017 / Accepted: 9 January 2017 / Published: 12 January 2017
(This article belongs to the Section Global Health)
Breast cancer is the most commonly diagnosed cancer among women. Therapeutic treatments for breast cancer generally include surgery, chemotherapy, radiotherapy, endocrinotherapy and molecular targeted therapy. With the development of molecular biology, immunology and pharmacogenomics, immunotherapy becomes a promising new field in breast cancer therapies. In this review, we discussed recent progress in breast cancer immunotherapy, including cancer vaccines, bispecific antibodies, and immune checkpoint inhibitors. Several additional immunotherapy modalities in early stages of development are also highlighted. It is believed that these new immunotherapeutic strategies will ultimately change the current status of breast cancer therapies. View Full-Text
Keywords: breast cancer; immunotherapy; cancer vaccines; bispecific antibodies; immune checkpoint inhibitors; stimulatory molecule agonists breast cancer; immunotherapy; cancer vaccines; bispecific antibodies; immune checkpoint inhibitors; stimulatory molecule agonists
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Yu, L.-Y.; Tang, J.; Zhang, C.-M.; Zeng, W.-J.; Yan, H.; Li, M.-P.; Chen, X.-P. New Immunotherapy Strategies in Breast Cancer. Int. J. Environ. Res. Public Health 2017, 14, 68.

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