Twelve-Months Follow-up of Supervised Exercise after Percutaneous Transluminal Angioplasty for Intermittent Claudication: A Randomised Clinical Trial
Abstract
:1. Introduction
2. Methods
2.1. Study Design
2.2. Sample and Sample Size Calculation
2.3. Ethical Considerations
2.4. Randomisation and Blinding
2.5. PTA and Post-Operative Care
2.6. Intervention
2.7. Assessments at Baseline and Follow-ups
2.8. Statistical Analysis
3. Results
Intervention group (n = 29) | Control group (n = 21) | |||
---|---|---|---|---|
Mean | (SD) | Mean | (SD) | |
or | or | |||
% | (n) | % | (n) | |
Demographics | ||||
Age (years) | 66.9 | (7.1) | 66 | (8.3) |
Body mass index (kg/m2) | 27.2 | (5) | 27.4 | (4) |
Gender (men) | 14 | (48.3) | 10 | (47.6) |
Marital status (married) | 18 | (62.1) | 10 | (47.6) |
Years of school (>9 years) | 22 | (75.9) | 16 | (76.2) |
Blood status | ||||
Total cholesterol (mmol/L) | 4.8 | (1) | 4.9 | (1.1) |
HDL 1 (mmol/L) | 1.7 | (0.6) | 1.6 | (0.6) |
LDL 1 (mmol/L) | 2.6 | (0.7) | 2.6 | (0.8) |
Triglycerides (mmol/L) | 1.3 | (0.6) | 1.5 | (1) |
HbA1c 1 (%) | 5.9 | (0.7) | 6.2 | (0.6) |
Smoking status | ||||
Have never smoked | 0 | (0) | 4.8 | (1) |
Used to smoke | 62.1 | (18) | 52.4 | (11) |
Currently smoke | 37.9 | (11) | 42.8 | (9) |
Current medication | ||||
Statins | 96.6 | (28) | 90.5 | (19) |
Platelet inhibitors | 86.2 | (25) | 95.2 | (20) |
Anticoagulants | 6.9 | (2) | 0 | (0) |
Hypertension | 51.7 | (15) | 61.9 | (13) |
Comorbidity | ||||
Diabetes | 10.3 | (4) | 19.0 | (4) |
COPD | 6.9 | (2) | 4.8 | (1) |
Previous cardiovascular events | ||||
Myocardial infarction | 27.6 | (8) | 38.1 | (8) |
Stroke/TIA 1 | 3.4 | (1) | 0 | (0) |
Peripheral arterial surgery or endovascular treatment | 17.2 | (5) | 19.0 | (4) |
3.1. Physical Function
3.2. Limb Hemodynamics
3.3. HRQoL
3.4. Medication and Adverse Events
4. Discussion
5. Conclusions
Acknowledgements
Conflicts of Interest
References
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Bø, E.; Hisdal, J.; Cvancarova, M.; Stranden, E.; Jørgensen, J.J.; Sandbæk, G.; Grøtta, O.J.; Bergland, A. Twelve-Months Follow-up of Supervised Exercise after Percutaneous Transluminal Angioplasty for Intermittent Claudication: A Randomised Clinical Trial. Int. J. Environ. Res. Public Health 2013, 10, 5998-6014. https://doi.org/10.3390/ijerph10115998
Bø E, Hisdal J, Cvancarova M, Stranden E, Jørgensen JJ, Sandbæk G, Grøtta OJ, Bergland A. Twelve-Months Follow-up of Supervised Exercise after Percutaneous Transluminal Angioplasty for Intermittent Claudication: A Randomised Clinical Trial. International Journal of Environmental Research and Public Health. 2013; 10(11):5998-6014. https://doi.org/10.3390/ijerph10115998
Chicago/Turabian StyleBø, Elisabeth, Jonny Hisdal, Milada Cvancarova, Einar Stranden, Jørgen J. Jørgensen, Gunnar Sandbæk, Ole J. Grøtta, and Astrid Bergland. 2013. "Twelve-Months Follow-up of Supervised Exercise after Percutaneous Transluminal Angioplasty for Intermittent Claudication: A Randomised Clinical Trial" International Journal of Environmental Research and Public Health 10, no. 11: 5998-6014. https://doi.org/10.3390/ijerph10115998