Next Article in Journal
Antitumor Peptides from Marine Organisms
Previous Article in Journal
Fucoxanthin, a Marine Carotenoid Present in Brown Seaweeds and Diatoms: Metabolism and Bioactivities Relevant to Human Health
Article Menu

Export Article

Open AccessArticle
Mar. Drugs 2011, 9(10), 1829-1839;

Polyhydroxylated Steroids from the Bamboo Coral Isis hippuris

Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan
Department of Microbiology, Kaohsiung Medical University, Kaohsiung 807, Taiwan
Centers for Asia-Pacific Ocean Research and Translational Biopharmaceuticals, National Sun Yat-sen University, Kaohsiung 804, Taiwan
Authors to whom correspondence should be addressed.
Received: 25 August 2011 / Revised: 24 September 2011 / Accepted: 30 September 2011 / Published: 10 October 2011
Full-Text   |   PDF [674 KB, uploaded 24 February 2015]


In previous studies on the secondary metabolites of the Taiwanese octocoral Isis hippuris, specimens have always been collected at Green Island. In the course of our studies on bioactive compounds from marine organisms, the acetone-solubles of the Taiwanese octocoral I. hippuris collected at Orchid Island have led to the isolation of five new polyoxygenated steroids: hipposterone M–O (13), hipposterol G (4) and hippuristeroketal A (5). The structures of these compounds were determined on the basis of their spectroscopic and physical data. The anti-HCMV (human cytomegalovirus) activity of 15 and their cytotoxicity against selected cell lines were evaluated. Compound 2 exhibited inhibitory activity against HCMV, with an EC50 value of 6.0 μg/mL. View Full-Text
Keywords: octocoral; Isis hippuris; anti-HCMV activity octocoral; Isis hippuris; anti-HCMV activity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Chen, W.-H.; Wang, S.-K.; Duh, C.-Y. Polyhydroxylated Steroids from the Bamboo Coral Isis hippuris. Mar. Drugs 2011, 9, 1829-1839.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top