Effects of Lissoclibadins and Lissoclinotoxins, Isolated from a Tropical Ascidian Lissoclinum cf. badium, on IL-8 production in a PMA-stimulated Promyelocytic Leukemia Cell Line
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Cell lines and culture conditions
2.4. Detection of human IL-8 by ELISA
2.5. Determination of cell proliferation
2.6. Determination of cytotoxicity
3. Results
3.1. Effects of compounds 1–7 on IL-8 production by PMA-stimulated HL-60 cells
3.2. Inhibition of cell proliferation and cytotoxicity of compounds 1–7 against HL-60 cells
4. Discussion
Acknowledgements
References
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Oda, T.; Fujiwara, T.; Liu, H.; Ukai, K.; Mangindaan, R.E.P.; Mochizuki, M.; Namikoshi, M. Effects of Lissoclibadins and Lissoclinotoxins, Isolated from a Tropical Ascidian Lissoclinum cf. badium, on IL-8 production in a PMA-stimulated Promyelocytic Leukemia Cell Line. Mar. Drugs 2006, 4, 15-21. https://doi.org/10.3390/md401015
Oda T, Fujiwara T, Liu H, Ukai K, Mangindaan REP, Mochizuki M, Namikoshi M. Effects of Lissoclibadins and Lissoclinotoxins, Isolated from a Tropical Ascidian Lissoclinum cf. badium, on IL-8 production in a PMA-stimulated Promyelocytic Leukemia Cell Line. Marine Drugs. 2006; 4(1):15-21. https://doi.org/10.3390/md401015
Chicago/Turabian StyleOda, Taiko, Takeshi Fujiwara, Hongwei Liu, Kazuyo Ukai, Remy E. P. Mangindaan, Masataka Mochizuki, and Michio Namikoshi. 2006. "Effects of Lissoclibadins and Lissoclinotoxins, Isolated from a Tropical Ascidian Lissoclinum cf. badium, on IL-8 production in a PMA-stimulated Promyelocytic Leukemia Cell Line" Marine Drugs 4, no. 1: 15-21. https://doi.org/10.3390/md401015