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Mar. Drugs 2019, 17(3), 183;

Biological Activities of Fucoidan and the Factors Mediating Its Therapeutic Effects: A Review of Recent Studies

Marine College, Shandong University, Weihai 264209, China
School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
Author to whom correspondence should be addressed.
Received: 1 March 2019 / Revised: 14 March 2019 / Accepted: 16 March 2019 / Published: 20 March 2019
(This article belongs to the Collection Marine Polysaccharides)
PDF [481 KB, uploaded 20 March 2019]


The marine acid polysaccharide fucoidan has attracted attention from both the food and pharmaceutical industries due to its promising therapeutic effects. Fucoidan is a polysaccharide that mainly consists of L-fucose and sulphate groups. Its excellent biological function is attributed to its unique biological structure. Classical activities include antitumor, antioxidant, anticoagulant, antithrombotic, immunoregulatory, antiviral and anti-inflammatory effects. More recently, fucoidan has been shown to alleviate metabolic syndrome, protect the gastrointestinal tract, benefit angiogenesis and bone health. This review focuses on the progress in our understanding of the biological activities of fucoidan, highlighting its benefits for the treatment of human disease. We hope that this review can provide some theoretical basis and inspiration for the product development of fucoidan. View Full-Text
Keywords: acid polysaccharide; fucoidan; biological structure; biological function acid polysaccharide; fucoidan; biological structure; biological function

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Wang, Y.; Xing, M.; Cao, Q.; Ji, A.; Liang, H.; Song, S. Biological Activities of Fucoidan and the Factors Mediating Its Therapeutic Effects: A Review of Recent Studies. Mar. Drugs 2019, 17, 183.

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