Next Article in Journal
Anti-Obesity and Anti-Diabetic Effect of Neoagarooligosaccharides on High-Fat Diet-Induced Obesity in Mice
Next Article in Special Issue
In Vitro Antioxidant Activities of Enzymatic Hydrolysate from Schizochytrium sp. and Its Hepatoprotective Effects on Acute Alcohol-Induced Liver Injury In Vivo
Previous Article in Journal
Biscembranoids and Cembranoids from the Soft Coral Sarcophyton elegans
Previous Article in Special Issue
Bioactive Peptide of Marine Origin for the Prevention and Treatment of Non-Communicable Diseases
Open AccessReview

Marine Peptides as Potential Agents for the Management of Type 2 Diabetes Mellitus—A Prospect

Dongguan Key Laboratory of Environmental Medicine, School of Public Health, Guangdong Medical University, Dongguan 523808, China
*
Author to whom correspondence should be addressed.
Academic Editor: Se-Kwon Kim
Mar. Drugs 2017, 15(4), 88; https://doi.org/10.3390/md15040088
Received: 30 January 2017 / Revised: 17 March 2017 / Accepted: 20 March 2017 / Published: 23 March 2017
(This article belongs to the Special Issue Marine Proteins and Peptides)
An increasing prevalence of diabetes is known as a main risk for human health in the last future worldwide. There is limited evidence on the potential management of type 2 diabetes mellitus using bioactive peptides from marine organisms, besides from milk and beans. We summarized here recent advances in our understanding of the regulation of glucose metabolism using bioactive peptides from natural proteins, including regulation of insulin-regulated glucose metabolism, such as protection and reparation of pancreatic β-cells, enhancing glucose-stimulated insulin secretion and influencing the sensitivity of insulin and the signaling pathways, and inhibition of bioactive peptides to dipeptidyl peptidase IV, α-amylase and α-glucosidase activities. The present paper tried to understand the underlying mechanism involved and the structure characteristics of bioactive peptides responsible for its antidiabetic activities to prospect the utilization of rich marine organism proteins. View Full-Text
Keywords: marine protein; bioactive peptide; regulation; glucose metabolism; structure active relationship marine protein; bioactive peptide; regulation; glucose metabolism; structure active relationship
Show Figures

Figure 1

MDPI and ACS Style

Xia, E.-Q.; Zhu, S.-S.; He, M.-J.; Luo, F.; Fu, C.-Z.; Zou, T.-B. Marine Peptides as Potential Agents for the Management of Type 2 Diabetes Mellitus—A Prospect. Mar. Drugs 2017, 15, 88. https://doi.org/10.3390/md15040088

AMA Style

Xia E-Q, Zhu S-S, He M-J, Luo F, Fu C-Z, Zou T-B. Marine Peptides as Potential Agents for the Management of Type 2 Diabetes Mellitus—A Prospect. Marine Drugs. 2017; 15(4):88. https://doi.org/10.3390/md15040088

Chicago/Turabian Style

Xia, En-Qin; Zhu, Shan-Shan; He, Min-Jing; Luo, Fei; Fu, Cheng-Zhan; Zou, Tang-Bin. 2017. "Marine Peptides as Potential Agents for the Management of Type 2 Diabetes Mellitus—A Prospect" Mar. Drugs 15, no. 4: 88. https://doi.org/10.3390/md15040088

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop