Preparation of Chito-Oligomers by Hydrolysis of Chitosan in the Presence of Zeolite as Adsorbent
AbstractAn increasing interest has recently been shown to use chitin/chitosan oligomers (chito-oligomers) in medicine and food fields because they are not only water-soluble, nontoxic, and biocompatible materials, but they also exhibit numerous biological properties, including antibacterial, antifungal, and antitumor activities, as well as immuno-enhancing effects on animals. Conventional depolymerization methods of chitosan to chito-oligomers are either chemical by acid-hydrolysis under harsh conditions or by enzymatic degradation. In this work, hydrolysis of chitosan to chito-oligomers has been achieved by applying adsorption-separation technique using diluted HCl in the presence of different types of zeolite as adsorbents. The chito-oligomers were retrieved from adsorbents and characterized by differential scanning calorimetry (DSC), liquid chromatography/mass spectroscopy (LC/MS), and ninhydrin test. View Full-Text
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Ibrahim, K.A.; El-Eswed, B.I.; Abu-Sbeih, K.A.; Arafat, T.A.; Al Omari, M.M.H.; Darras, F.H.; Badwan, A.A. Preparation of Chito-Oligomers by Hydrolysis of Chitosan in the Presence of Zeolite as Adsorbent. Mar. Drugs 2016, 14, 43.
Ibrahim KA, El-Eswed BI, Abu-Sbeih KA, Arafat TA, Al Omari MMH, Darras FH, Badwan AA. Preparation of Chito-Oligomers by Hydrolysis of Chitosan in the Presence of Zeolite as Adsorbent. Marine Drugs. 2016; 14(8):43.Chicago/Turabian Style
Ibrahim, Khalid A.; El-Eswed, Bassam I.; Abu-Sbeih, Khaleel A.; Arafat, Tawfeeq A.; Al Omari, Mahmoud M.H.; Darras, Fouad H.; Badwan, Adnan A. 2016. "Preparation of Chito-Oligomers by Hydrolysis of Chitosan in the Presence of Zeolite as Adsorbent." Mar. Drugs 14, no. 8: 43.
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