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Volume 12
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10.3390/md12031271
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Communication

Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B

by
Khanitha Pudhom
1,*,
Thapong Teerawatananond
1 and
Supichar Chookpaiboon
2
1
Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand
2
Program in Biotechnology, Faculty of Science, Chulalongkorn Universtiy, Bangkok 10330, Thailand
*
Author to whom correspondence should be addressed.
Mar. Drugs 2014, 12(3), 1271-1280; https://doi.org/10.3390/md12031271
Submission received: 6 January 2014 / Revised: 8 February 2014 / Accepted: 18 February 2014 / Published: 6 March 2014
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Abstract

Three new spirobisnaphthalenes (1–3) were isolated from the mangrove-derived fungus Rhytidhysteron sp., together with five known derivatives (4–8). The structures of the compounds were established on the basis of extensive spectroscopic data, and the relative configurations of their stereogenic carbons were determined by a single-crystal X-ray crystallographic analysis. Compounds 3–5 displayed cytotoxicity against both cancer cell lines, MCF-7 and CaSki, while 2 was active only on CaSKi cells.
Keywords: endophytic fungus; Rhytidhysteron sp.; spirobisnaphthalene; cytotoxicity endophytic fungus; Rhytidhysteron sp.; spirobisnaphthalene; cytotoxicity

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MDPI and ACS Style

Pudhom, K.; Teerawatananond, T.; Chookpaiboon, S. Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B. Mar. Drugs 2014, 12, 1271-1280. https://doi.org/10.3390/md12031271

AMA Style

Pudhom K, Teerawatananond T, Chookpaiboon S. Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B. Marine Drugs. 2014; 12(3):1271-1280. https://doi.org/10.3390/md12031271

Chicago/Turabian Style

Pudhom, Khanitha, Thapong Teerawatananond, and Supichar Chookpaiboon. 2014. "Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B" Marine Drugs 12, no. 3: 1271-1280. https://doi.org/10.3390/md12031271

APA Style

Pudhom, K., Teerawatananond, T., & Chookpaiboon, S. (2014). Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B. Marine Drugs, 12(3), 1271-1280. https://doi.org/10.3390/md12031271

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