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Mar. Drugs 2014, 12(12), 6142-6177;

Synthetic Approaches to the Lamellarins—A Comprehensive Review

Institute of Organic Chemistry, Johannes Gutenberg-University Mainz, Duesbergweg 10-14, 55128 Mainz, Germany
Author to whom correspondence should be addressed.
Received: 3 November 2014 / Revised: 1 December 2014 / Accepted: 5 December 2014 / Published: 18 December 2014
(This article belongs to the Special Issue Synthesis around Marine Natural Products)


The present review discusses the known synthetic routes to the lamellarin alkaloids published until 2014. It begins with syntheses of the structurally simpler type-II lamellarins and then focuses on the larger class of the 5,6-saturated and -unsaturated type-I lamellarins. The syntheses are grouped by the strategy employed for the assembly of the central pyrrole ring. View Full-Text
Keywords: lamellarins; pyrroles; alkaloids; marine natural products; total synthesis lamellarins; pyrroles; alkaloids; marine natural products; total synthesis

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Imbri, D.; Tauber, J.; Opatz, T. Synthetic Approaches to the Lamellarins—A Comprehensive Review. Mar. Drugs 2014, 12, 6142-6177.

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