Next Article in Journal
Five New Amicoumacins Isolated from a Marine-Derived Bacterium Bacillus subtilis
Previous Article in Journal
Tetrodotoxin (TTX) as a Therapeutic Agent for Pain
Article Menu

Export Article

Open AccessArticle

New Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae

Department of Microbiology, Kaohsiung Medical University, Kaohsiung 807, Taiwan
Department of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung 804, Taiwan
Asia-Pacific Ocean Research Center, National Sun Yat-Sen University, Kaohsiung 804, Taiwan
Author to whom correspondence should be addressed.
Mar. Drugs 2012, 10(2), 306-318;
Received: 23 December 2011 / Revised: 20 January 2012 / Accepted: 20 January 2012 / Published: 31 January 2012
PDF [874 KB, uploaded 24 February 2015]


Six new cembranolides, michaolides L–Q (16), and a known cembranolide, lobomichaolide (7) were isolated from the CH2Cl2 extract of the soft coral Lobophytum michaelae. Their structures were established by extensive spectral analysis. The anti-HCMV (human cytomegalovirus) activity of 17 and their cytotoxicity against selected cell lines were evaluated. View Full-Text
Keywords: Lobophytum michaelae; cembranolides; cytotoxicity Lobophytum michaelae; cembranolides; cytotoxicity

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Wang, S.-K.; Duh, C.-Y. New Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae. Mar. Drugs 2012, 10, 306-318.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top