GERD after Roux-en-Y Gastric Bypass: Prevalence and Risk Factors Analysis
Abstract
1. Introduction
2. Materials and Methods
Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Characteristics | Patients (n = 180) |
---|---|
Age, y mean (SD) | 42.7 (10.5) |
Sex, M/F | 52/128 |
BMI, kg/m2 mean (SD) | 45.2 (6.4) |
Waist circumference, cm mean (SD) | 127.1 (15.6) |
Smoking n (%) | 59 (32.7) |
Erosive esophagitis n (%) | 49 (27.2) |
Hiatal hernia n (%) | 37 (20.6) |
GERD-HRQL score, median (min/max) | 3.0 (8.0) |
PPI use n (%) | 37 (20.6) |
GERD n (%) | 74 (41.1) |
Hypertension n (%) | 108 (60) |
Diabetes mellitus n (%) | 14 (7.8) |
Dyslipidemia n (%) | 131 (72.8) |
GERD before Surgery | GERD after Surgery | p = 0.717 | |
---|---|---|---|
Yes | No | Total | |
Yes | 12 | 42 | 54 |
No | 18 | 54 | 72 |
Total | 30 | 96 | 126 |
Baseline n = 179 | 1 Year n = 97 | 12 Years n = 126 | p Value B vs. 1 y | p Value B vs. 12 y | p Value 1 y vs. 12 y | |
---|---|---|---|---|---|---|
GERD-HRQL score | <0.001 | 0.028 | <0.001 | |||
Median (IR) | 3.0 (9.0) | 0.0 (1.0) | 2.0 (5.0) | |||
Mean (SD) | 5.07 (5.21) | 0.98 (2.52) | 3.94 (4.77) | |||
GSRS Diarrhea score | 0.143 | <0.001 | 0.002 | |||
Median (IR) | 1.33 (0.67) | 1.0 (0.67) | 1.5 (2.42) | |||
Mean (SD) | 1.63 (0.84) | 1.46 (0.84) | 2.37 (1.78) | |||
GSRS Indigestion score | <0.001 | 0.398 | <0.001 | |||
Median (IR) | 2.0 (1.25) | 1.25 (0.75) | 2.25 (1.25) | |||
Mean (SD) | 2.29 (0.97) | 1.45 (0.59) | 2.40 (0.80) | |||
GSRS Constipation score | 0.433 | 0.204 | 0.917 | |||
Median (IR) | 1.33 (1.33) | 1.17 (1.0) | 1.0 (1.0) | |||
Mean (SD) | 1.81 (0.99) | 1.53 (0.75) | 1.67 (1.19) | |||
GSRS Pain score | <0.001 | <0.001 | 0.713 | |||
Median (IR) | 1.67 (1.0) | 1.0 (0.67) | 1.0 (0.33) | |||
Mean (SD) | 1.85 (0.80) | 1.38 (0.61) | 1.32 (0.61) | |||
GSRS Reflux score | <0.001 | 0.162 | <0.001 | |||
Median (IR) | 1.0 (1.0) | 1.0 (0.0) | 1.0 (1.0) | |||
Mean (SD) | 1.62 (0.90) | 1.09 (0.29) | 1.48 (0.95) | |||
Uncontrolled Eating score | <0.001 | <0.001 | <0.001 | |||
Median (IR) | 51.85 (22.22) | 25.93 (7.41) | 40.74 (33.33) | |||
Mean (SD) | 50.99 (15.58) | 29.63 (9.93) | 38.83 (18.48) | |||
Cognitive Restraint score | 0.007 | 0.339 | 0.107 | |||
Median (IR) | 52.78 (11.11) | 55.56 (11.11) | 55.56 (16.67) | |||
Mean (SD) | 51.94 (10.12) | 55.44 (8.14) | 53.53 (11.34) | |||
Emotional Eating score | <0.001 | <0.001 | <0.001 | |||
Median (IR) | 44.44 (44.44) | 11.11 (11.11) | 33.33 (22.22) | |||
Mean (SD) | 46.93 (28.74) | 20.14 (22.01) | 31.22 (14.38) |
Factor | Univariate Model | Multivariate Model | |||
---|---|---|---|---|---|
N | Beta (95% CI) | p Value | Beta (95% CI) | p Value | |
Sex (Ref = male) | 126 | 1.25 (0.50, 3.13) | 0.633 | ||
Age, years (Ref ≤ 55.6) | 126 | 1.28 (0.56, 2.92) | 0.559 | ||
BMI kg/m2 (Ref ≤ 31.7) | 120 | 1.88 (0.78, 4.51) | 0.157 | ||
%EBMIL (Ref > 39.9) | 120 | 0.79 (0.24, 2.60) | 0.700 | ||
%TWL (Ref > 18.7) | 120 | 0.78 (0.26, 2.32) | 0.658 | ||
%Weight regain (Ref ≤ 11.0) | 120 | 3.22 (1.19, 8.67) | 0.021 | 3.22 (1.13, 9.22) | 0.029 |
Uncontrolled eating (Ref ≤ 47.0) | 126 | 2.00 (0.87, 4.60) | 0.103 | ||
Cognitive restraint (Ref ≤ 41.7) | 126 | 1.50 (0.47, 4.84) | 0.497 | ||
Emotional eating (Ref ≤ 38.9) | 126 | 0.82 (0.31, 2.14) | 0.684 | ||
GSRS Diarrhea score (Ref ≤ 3.20) | 126 | 5.31 (2.19, 12.91) | <0.001 | 3.21 (1.14, 9.06) | 0.027 |
GSRS Indigestion score (Ref ≤ 2.15) | 126 | 4.73 (1.77, 12.60) | 0.002 | 2.45 (0.81, 7.42) | 0.113 |
GSRS Constipation score (Ref ≤ 1.5) | 126 | 0.86 (0.35, 2.01) | 0.734 | ||
Preoperative GERD (Ref = no) | 126 | 1.17 (0.51, 2.69) | 0.717 | ||
Hiatal hernia, (Ref = no) | 106 | 0.62 (0.16, 2.34) | 0.475 |
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Pažusis, M.; Gerasimovič, G.; Petereit, R.; Gudaitytė, R.; Maleckas, A. GERD after Roux-en-Y Gastric Bypass: Prevalence and Risk Factors Analysis. Medicina 2024, 60, 1221. https://doi.org/10.3390/medicina60081221
Pažusis M, Gerasimovič G, Petereit R, Gudaitytė R, Maleckas A. GERD after Roux-en-Y Gastric Bypass: Prevalence and Risk Factors Analysis. Medicina. 2024; 60(8):1221. https://doi.org/10.3390/medicina60081221
Chicago/Turabian StylePažusis, Matas, Gabrielė Gerasimovič, Rūta Petereit, Rita Gudaitytė, and Almantas Maleckas. 2024. "GERD after Roux-en-Y Gastric Bypass: Prevalence and Risk Factors Analysis" Medicina 60, no. 8: 1221. https://doi.org/10.3390/medicina60081221
APA StylePažusis, M., Gerasimovič, G., Petereit, R., Gudaitytė, R., & Maleckas, A. (2024). GERD after Roux-en-Y Gastric Bypass: Prevalence and Risk Factors Analysis. Medicina, 60(8), 1221. https://doi.org/10.3390/medicina60081221