Effect of a Single Dose of Deflazacort on Postoperative Pain, Swelling, and Trismus after Impacted Lower Third Molar Surgery: Randomised Clinical Trial
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Sample
2.2. Outcome Variables
2.3. Patient Allocation
2.4. Surgical Procedure
2.5. Data Collection
2.6. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Inclusion Criteria | Exclusion Criteria |
---|---|
* ASA 1, healthy * 18–40 years old * Bilateral impacted lower 3rd molars * Mesioangular (Angulation) * Class II and Class B (level of impaction) | * Systemic disease that interferes with surgical treatment * Smokers * Alcohol drinkers * Substance abusers * Pregnant and breastfeeding mothers * Patients with facial asymmetry * Patients currently receiving anti-inflammatory medication |
Gender | Male (%) | 12 (46.2) |
Female (%) | 14 (53.8) | |
Age (year) | Min–Max (Median) | 18–35 (22.5) |
Mean ± SD | 23.31 ± 5.01 |
6th Hour | 12th Hour | 24th Hour | 2nd Day | 3rd Day | 4th Day | 5th Day | 6th Day | 7th Day | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean ± SD | Median | Mean ± SD | Median | Mean ± SD | Median | Mean ± SD | Median | Mean ± SD | Median | Mean ± SD | Median | Mean ± SD | Median | Mean ± SD | Median | Mean ± SD | Median | |
Group 1 | 5.8 ± 2.1 | 6.00 | 4.81 ± 2.19 | 5.0 | 4.35 ± 3.02 | 5.0 | 3.92 ± 2.64 | 3.0 | 3.04 ± 2.72 | 2.5 | 1.96 ± 2.22 | 1.5 | 1.46 ± 1.90 | 0.5 | 1.04 ± 1.28 | 0.0 | 0.85 ± 1.54 | 0.0 |
Group 2 | 3.1 ± 1.6 | 3.00 | 3.27 ± 2.49 | 3.0 | 4.27 ± 2.71 | 5.0 | 4.04 ± 2.68 | 4.0 | 2.73 ± 2.41 | 2.0 | 1.77 ± 2.10 | 1.5 | 0.85 ± 1.26 | 0.0 | 0.65 ± 1.02 | 0.0 | 0.50 ± 0.81 | 0.0 |
p | 1 0.000 * | 1 0.025 * | 1 0.912 | 1 0.861 | 1 0.773 | 1 0.832 | 1 0.276 | 1 0.290 | 1 0.520 |
n | Mean | SD | Median | Minimum | Maximum | p | |||
---|---|---|---|---|---|---|---|---|---|
Maximum mouth opening (%) | Day 2 | Group 1 | 26 | −31.93 | 15.25 | −30.59 | −60 | −4.08 | 1 0.701 |
Group 2 | 26 | −32.91 | 14.28 | −34.52 | −55.56 | 0.00 | |||
Day 7 | Group 1 | 26 | −13.17 | 11.75 | −9.05 | −43.75 | 0.00 | 1 0.203 | |
Group 2 | 26 | −17.22 | 11.99 | −15.65 | −41.67 | −2.04 | |||
n | Mean | SD | Median | Minimum | Maximum | p | |||
Maximum mouth opening (mm) | Pre-op | Group 1 and Group 2 | 26 | 44.5 | 5.13 | 45 | 31 | 55 | 1 0.999 |
Day 2 | Group 1 | 26 | 30.15 | 7.17 | 30.00 | 16 | 47 | 1 0.652 | |
Group 2 | 26 | 29.35 | 4.33 | 29.00 | 20 | 36 | |||
Day 7 | Group 1 | 26 | 38.54 | 6.56 | 38.00 | 25 | 55 | 1 0.478 | |
Group 2 | 26 | 36.58 | 5.36 | 38.00 | 28 | 48 |
Group 1 (%) | Group 2 (%) | Grup 1 (mm) | Grup 2 (mm) | p | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Mean ± SD | Median | Mean ± SD | Median | Mean ± SD | Median | Mean ± SD | Median | |||
Day 2 Distance | 4.12 ± 2.13 | 3.67 | 3.07 ± 2.37 | 3.05 | 112.94 ± 9.22 | 112.83 | 111.68 ± 7.34 | 111.33 | 1 0.089 | |
Day 7 Distance | 1.74 ± 1.80 | 1.12 | 1.44 ± 1.71 | 0.91 | 110.36 ± 8.93 | 109.67 | 109.95 ± 7.70 | 110.17 | 1 0.349 |
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Kaplan, V.; Ciğerim, L.; Feslihan, E.; Çınarsoy Ciğerim, S. Effect of a Single Dose of Deflazacort on Postoperative Pain, Swelling, and Trismus after Impacted Lower Third Molar Surgery: Randomised Clinical Trial. Medicina 2024, 60, 1206. https://doi.org/10.3390/medicina60081206
Kaplan V, Ciğerim L, Feslihan E, Çınarsoy Ciğerim S. Effect of a Single Dose of Deflazacort on Postoperative Pain, Swelling, and Trismus after Impacted Lower Third Molar Surgery: Randomised Clinical Trial. Medicina. 2024; 60(8):1206. https://doi.org/10.3390/medicina60081206
Chicago/Turabian StyleKaplan, Volkan, Levent Ciğerim, Erkan Feslihan, and Saadet Çınarsoy Ciğerim. 2024. "Effect of a Single Dose of Deflazacort on Postoperative Pain, Swelling, and Trismus after Impacted Lower Third Molar Surgery: Randomised Clinical Trial" Medicina 60, no. 8: 1206. https://doi.org/10.3390/medicina60081206
APA StyleKaplan, V., Ciğerim, L., Feslihan, E., & Çınarsoy Ciğerim, S. (2024). Effect of a Single Dose of Deflazacort on Postoperative Pain, Swelling, and Trismus after Impacted Lower Third Molar Surgery: Randomised Clinical Trial. Medicina, 60(8), 1206. https://doi.org/10.3390/medicina60081206