Association between Circle of Willis Configuration and Rupture of Cerebral Aneurysms
Abstract
:1. Introduction
2. Material and Methods
Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Configuration of the Circle of Willis | Autopsied Patients n = 56 | Surgically Treated Patients n = 114 | p-Values 1 | |
---|---|---|---|---|
Symmetric Willis—Type A and Type C | 41(73.2%) | 41 (36.0%) | <0.001 | |
Asymmetric Willis—Type B and Type D | 15 (26.8%) | 73 (64.0%) | ||
Asymmetric Willis—Type B | Changes in the A1 segment | 9(16.0%) | 50 (43.9 %) | 0.737 |
Asymmetric Willis—Type D | Changes in the posterior segments | 6(10.8%) | 23 (20.2%) |
Type Circle of Willis | Autopsied Patients | Surgically Treated Patients | p-Value 1 | ||||
---|---|---|---|---|---|---|---|
Solitary Aneurysm | Multiple Aneurysms | ||||||
Type A | 27 | (48.2%) | 20 | (24.7%) 2 | 5 | (15.2%) 2 | 0.001 |
Type B | 4 | (16.0%) | 32 | (42.0%) 2 | 15 | (51.5%) 2 | <0.001 |
subtype B/D | 5 | 2 | 2 | ||||
Type C | 14 | (25.0%) | 13 | (16.0%) | 3 | (9%) | 0.143 |
Type D | 6 | (10.8%) | 14 | (17.3%) | 8 | (24.3%) | 0.242 |
Σ | 56 | (100%) | 81 | (100.0%) | 33 | (100%) |
Types Willis | Multiple Aneurysms Locations of Ruptured Aneurysms | Σ | |||||
ACoA | MCA | ICA | PCoA | perA | VBA | ||
Type A | 0 | 3 | 1 | 1 | 0 | 0 | 5 (15.2%) |
Type B | 12 | 0 | 3 | 0 | 0 | 0 | 17 (51.5%) |
Sub type B/D | 0 | 0 | 0 | 2 | 0 | 0 | |
Type C | 0 | 1 | 2 | 0 | 0 | 0 | 3 (9.0%) |
Type D | 0 | 6 | 0 | 2 | 0 | 0 | 8 (24.3%) |
Σ | 12 | 10 | 6 | 5 | 0 | 0 | 33 (100.0%) |
Type Willis | Locations of Solitary Ruptured Aneurysms | Σ | |||||
ACoA | MCA | ICA | PCoA | perA | VBA | ||
Type A | 9 | 5 | 2 | 2 | 1 | 1 | 20 (24.7%) |
Type B | 24 | 3 | 2 | 0 | 3 | 0 | 34 (42.0%) |
subtype B/D | 0 | 0 | 0 | 2 | 0 | 0 | |
Type C | 0 | 8 | 2 | 2 | 0 | 1 | 13 (16.0%) |
Type D | 0 | 4 | 24 | 6 | 0 | 0 | 14 (17.3%) |
Σ | 33 | 20 | 10 | 12 | 4 | 2 | 81 (100.0%) |
Locations Ruptured Aneurysms | Ruptured Aneurysm in the Surgically Treated Group | Hypoplasia A1 Right | Hypoplasia A1 Left | p-Value 1 |
---|---|---|---|---|
ACoA | 36 (72%) | 25 (80.6%) | 11 (57.9%) | 0.157 |
MCA | 3 (6%) | 1 (3.2%) | 2 (10.5%) | 0.549 2 |
ICA | 5 (10%) | 1 (3.2%) | 4 (21.1%) | 0.062 2 |
PCoA | 3 (6%) | 2 (6.5%) | 1 (5.3%) | 1.000 2 |
perA | 3 (6%) | 2 (6.5%) | 1 (5.3%) | 1.000 2 |
Surgically treated group | 50 (43.8%) 3 | 31 (62%) | 19 (38%) | <0.001 1,4 |
Autopsied group | 9 (16.1%) 3 | 5 (55.6%) | 4 (44.4%) |
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Stojanović, N.N.; Kostić, A.; Mitić, R.; Berilažić, L.; Radisavljević, M. Association between Circle of Willis Configuration and Rupture of Cerebral Aneurysms. Medicina 2019, 55, 338. https://doi.org/10.3390/medicina55070338
Stojanović NN, Kostić A, Mitić R, Berilažić L, Radisavljević M. Association between Circle of Willis Configuration and Rupture of Cerebral Aneurysms. Medicina. 2019; 55(7):338. https://doi.org/10.3390/medicina55070338
Chicago/Turabian StyleStojanović, Nebojša N., Aleksandar Kostić, Radisav Mitić, Luka Berilažić, and Miša Radisavljević. 2019. "Association between Circle of Willis Configuration and Rupture of Cerebral Aneurysms" Medicina 55, no. 7: 338. https://doi.org/10.3390/medicina55070338