Diagnostic Value of Conventional Visual Evoked Potentials Applied to Patients With Multiple Sclerosis
Abstract
Material and Methods. Pattern shift visual evoked potentials were recorded in 63 patients with multiple sclerosis, 17 (27%) of whom had a history of optic neuritis, and in 63 control patients with other neurological diseases. The latencies and amplitudes of P100 were measured. In total, 126 patients were referred to the inpatient department of neurology for differential diagnosis of demyelinating disorders between January and December of 2007.
Results. Abnormalities of visual evoked potentials were observed by 73% more frequently in patients with multiple sclerosis than in control patients (α=0.05, β<0.01). The combined monocular/ interocular test showed a specificity of 90.5% and a sensitivity of 82.5%. The probability of an affection of the pyramidal system was 5 times greater (95% CI, 2.2–11.0; P<0.01) and the probability of the optic pathways involvement was 4.8 times greater (95% CI, 1.9–11.9; P<0.01) in patients with multiple sclerosis than in controls.
Conclusion. Conventional visual evoked potentials must be reappraised in light of their diagnostic value in multiple sclerosis given their high diagnostic efficiency, relatively easy, short, and cheap implementation, and easy availability in everyday clinical practice.
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Balnytė, R.; Ulozienė, I.; Rastenytė, D.; Vaitkus, A.; Malcienė, L.; Laučkaitė, K. Diagnostic Value of Conventional Visual Evoked Potentials Applied to Patients With Multiple Sclerosis. Medicina 2011, 47, 37. https://doi.org/10.3390/medicina47050037
Balnytė R, Ulozienė I, Rastenytė D, Vaitkus A, Malcienė L, Laučkaitė K. Diagnostic Value of Conventional Visual Evoked Potentials Applied to Patients With Multiple Sclerosis. Medicina. 2011; 47(5):37. https://doi.org/10.3390/medicina47050037
Chicago/Turabian StyleBalnytė, Renata, Ingrida Ulozienė, Daiva Rastenytė, Antanas Vaitkus, Lina Malcienė, and Kristina Laučkaitė. 2011. "Diagnostic Value of Conventional Visual Evoked Potentials Applied to Patients With Multiple Sclerosis" Medicina 47, no. 5: 37. https://doi.org/10.3390/medicina47050037