Wearable Electronic Tongue for Non-Invasive Assessment of Human Sweat
Abstract
:1. Introduction
2. Materials and Methods
2.1. Chemicals and Materials
2.2. Electrochemical Measurements
2.3. Statistical Analysis
2.4. 1H-NMR
3. Results
3.1. Characterization of Electronic Tongue in Complex Buffer and Physiological Fluids
3.2. Wearable E-Tongue for On-Body Sweat Characterization
3.3. NMR-Analysis of Sweat Samples Characterized by the Wearable E-Tongue
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Compound | Concentration (mM) |
---|---|
Lactate | 5–40 (Ref [45]) |
Glucose | 0.1–2 (Ref [38,39]) |
Sodium carbonate | 0.5–100 (Ref [36,43]) |
Na+, Cl− | below 10, above 100 (Ref [9,10]) |
Urea | 5– above 100 (Ref [14,45]) |
Ascorbic acid | 0.01–0.5 (Ref [45,46]) |
Compound | PC 1 | PC 2 | PC 3 | PC 4 | PC 5 |
---|---|---|---|---|---|
Sweat | 0.61 | 0.34 | 0.40 | −0.44 | 0.03 |
Lac | −0.89 | 0.12 | −0.15 | −0.01 | −0.09 |
NaCarb | −0.81 | −0.52 | 0.09 | 0.10 | −0.06 |
Glc | −0.86 | 0.25 | −0.01 | 0.11 | 0.06 |
Ur | −0.42 | 0.70 | −0.05 | −0.35 | −0.02 |
AA | −0.30 | 0.69 | −0.01 | 0.37 | 0.40 |
NaCl | 0.45 | 0.74 | −0.01 | 0.19 | −0.27 |
SweatFirst | 0.93 | −0.18 | 0.22 | 0.4 | −0.07 |
SweatLast | 0.61 | −0.24 | −0.61 | -0.3 | 0.28 |
Sample | Sweat | Lac | NaCarb | Glc | Ur | AA | NaCl | SweatFirst | SweatLast |
---|---|---|---|---|---|---|---|---|---|
Sweat | 0 | 2.823 | 3.163 | 2.643 | 1.409 | 1.901 | 0.846 | 0.632 | 1.602 |
Lac | 0 | 0.492 | 0.393 | 0.687 | 1.184 | 2.278 | 3.533 | 2.728 | |
NaCarb | 0 | 1.242 | 1.862 | 2.003 | 3.230 | 3.142 | 2.680 | ||
Glc | 0 | 0.614 | 0.684 | 2.070 | 3.430 | 2.805 | |||
Ur | 0 | 0.702 | 1.117 | 2.792 | 2.457 | ||||
AA | 0 | 1.039 | 2.611 | 2.183 | |||||
NaCl | 0 | 1.176 | 1.673 | ||||||
SweatFirst | 0 | 0.902 | |||||||
SweatLast | 0 |
Metabolite | Chemical Shift (δ) | Area, First | Area, Last |
---|---|---|---|
Lactate | 4.11 (q), 1.32 (d) | 1.0 | 5.9 |
Serine | 3.96 (m), 3.85 (m) | trace | trace |
Alanine | 3.79 (q), 1.48 (d) | trace | trace |
Glycerol | 3.77 (m), 3.65 (m), 3.55 (m) | 0.5 | 0.6 |
Pyruvate | 2.37 (s) | trace | trace |
Lipids (-CH2-) | 1.28 (broad) | trace | trace |
Lipids/Protein (CH3-) | 1.15 (broad) | trace | trace |
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Falk, M.; Nilsson, E.J.; Cirovic, S.; Tudosoiu, B.; Shleev, S. Wearable Electronic Tongue for Non-Invasive Assessment of Human Sweat. Sensors 2021, 21, 7311. https://doi.org/10.3390/s21217311
Falk M, Nilsson EJ, Cirovic S, Tudosoiu B, Shleev S. Wearable Electronic Tongue for Non-Invasive Assessment of Human Sweat. Sensors. 2021; 21(21):7311. https://doi.org/10.3390/s21217311
Chicago/Turabian StyleFalk, Magnus, Emelie J. Nilsson, Stefan Cirovic, Bogdan Tudosoiu, and Sergey Shleev. 2021. "Wearable Electronic Tongue for Non-Invasive Assessment of Human Sweat" Sensors 21, no. 21: 7311. https://doi.org/10.3390/s21217311