Association between the Degree of Pre-Synaptic Dopaminergic Pathway Degeneration and Motor Unit Firing Behavior in Parkinson’s Disease Patients
Abstract
1. Introduction
2. Materials and Methods
2.1. Subjects
2.2. Muscle Strength Testing and Physical Symptom Assessment
2.3. Electromyography (EMG) Recording
2.4. Data Processing
2.5. DAT-SPECT
2.6. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variables | Females with Parkinson’s Disease |
---|---|
Age, years | 72.6 ± 7.2 |
Height, cm | 157.1 ± 10.2 |
Weight, kg | 58.3 ± 6.8 |
Disease duration, year | 3.5 ± 2.1 |
MMSE | 26.6 ± 1.4 |
UPDRS Part III | 9.9 ± 9.1 |
L-dopa, mg/day | 300 (100–300) |
Knee extensor muscle strength, Nm More-/Less-affected side | 54.3 ± 9.9/72.9 ± 20.5 * |
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Nishikawa, Y.; Watanabe, K.; Holobar, A.; Takahashi, T.; Maeda, N.; Maruyama, H.; Tanaka, S.; Hyngstrom, A.S. Association between the Degree of Pre-Synaptic Dopaminergic Pathway Degeneration and Motor Unit Firing Behavior in Parkinson’s Disease Patients. Sensors 2021, 21, 6615. https://doi.org/10.3390/s21196615
Nishikawa Y, Watanabe K, Holobar A, Takahashi T, Maeda N, Maruyama H, Tanaka S, Hyngstrom AS. Association between the Degree of Pre-Synaptic Dopaminergic Pathway Degeneration and Motor Unit Firing Behavior in Parkinson’s Disease Patients. Sensors. 2021; 21(19):6615. https://doi.org/10.3390/s21196615
Chicago/Turabian StyleNishikawa, Yuichi, Kohei Watanabe, Aleš Holobar, Tetsuya Takahashi, Noriaki Maeda, Hirofumi Maruyama, Shinobu Tanaka, and Allison S Hyngstrom. 2021. "Association between the Degree of Pre-Synaptic Dopaminergic Pathway Degeneration and Motor Unit Firing Behavior in Parkinson’s Disease Patients" Sensors 21, no. 19: 6615. https://doi.org/10.3390/s21196615
APA StyleNishikawa, Y., Watanabe, K., Holobar, A., Takahashi, T., Maeda, N., Maruyama, H., Tanaka, S., & Hyngstrom, A. S. (2021). Association between the Degree of Pre-Synaptic Dopaminergic Pathway Degeneration and Motor Unit Firing Behavior in Parkinson’s Disease Patients. Sensors, 21(19), 6615. https://doi.org/10.3390/s21196615